Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$120K - $145K *
Lead the charge in transforming complex revenue-cycle challenges into robust, production-ready AI models, ensuring statistical integrity and operational reliability while managing end-to-end data pipe...
Reposted yesterday
$81K - $129K *
Drive impactful health program analysis by leveraging actuarial expertise, performing data analysis, and supporting pricing strategies. Collaborate with cross-functional teams to enhance financial for...
Reposted 4 weeks ago
$80K - $95K *
Optimize your career as a Financial Analyst, driving category P&L management, revenue forecasting, and strategic financial insights. Collaborate with cross-functional teams to enhance decision-making...
6 days ago
Vice President, Self-Pay Performance & Client Strategy
$179K - $280K *
Unlock potential by driving strategic revenue cycle performance and enhancing client partnerships. Lead initiatives across Self-Pay and Patient Financial Experience, leveraging data to influence decis...
4 weeks ago
Analyst, Financial Planning & Analysis
$108K - $148K *
Join us as a Senior FP&A Analyst to drive financial planning, reporting, and forecasting. Collaborate across teams to optimize spending and enhance our financial systems, leveraging AI for insights th...
3 weeks ago
Senior Statistical Programmer/Analyst Consultant (Need solid oncology background) Remote in US
$110K - $130K *
Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...
2 weeks ago
$99K - $139K *
Join a dynamic team to develop and maintain innovative web applications, enhancing user experience and security. Collaborate with stakeholders to gather requirements, create documentation, and ensure...
Yesterday
Healthcare Tech Manager - Epic Patient Access
$130K - $150K *
Drive impactful solutions as a Healthcare Technology Manager, optimizing Epic Patient Access systems. Collaborate with clients and teams to enhance workflows and deliver sustainable results in a suppo...
2 weeks ago
$75K - $158K *
Empower cross-functional teams as a Business Analyst, driving Agile practices, refining backlogs, and aligning business objectives with technical execution to enhance project outcomes and stakeholder...
Reposted 2 weeks ago
$75K - $158K *
Transform business objectives into actionable insights by leveraging Agile methodologies. Collaborate with cross-functional teams to refine backlogs, create user stories, and ensure alignment between...
2 days ago
$75K - $158K *
Empower cross-functional teams by analyzing requirements, facilitating Agile processes, and ensuring alignment between business goals and technical execution. Drive effective backlog management and su...
2 days ago
$72K - $116K *
Reimagine financial analysis by supporting Sales Incentive Plans, ensuring alignment with enrollment and financial goals. Collaborate with leaders and stakeholders to enhance accuracy, efficiency, and...
Reposted 2 days ago
$135K - $145K *
Drive innovative software solutions by developing robust, cloud-native systems that enhance provider data management capabilities and meet the evolving needs of clients in a dynamic, collaborative env...
Reposted 6 days ago
Senior Analyst - Strategy, Analytics & Reporting
$109K - $125K *
Optimize enterprise strategy and analytics by transforming complex data into actionable insights. Collaborate across functions to enhance decision-making and support strategic initiatives through effe...
Today
Client Success Manager, Payer Retrieval
$108K - $130K *
Unlock your potential by leading customer projects, ensuring seamless communication, and driving success in healthcare solutions. Collaborate with diverse teams to enhance client satisfaction and oper...
2 weeks ago
$173K - $245K *
Unlock insights through data analytics and experimentation to enhance credit risk management. Collaborate with cross-functional teams to optimize policies, monitor performance, and drive strategic gro...
4 weeks ago
$95K - $115K *
Champion healthcare solutions by managing integrations and providing expert support. Drive projects and improve processes as a Senior Interface Analyst in a dynamic and innovative environment, ensurin...
Reposted 1 week ago
$160K - $175K *
Unlock potential by leading the design and implementation of scalable analytics solutions. Collaborate with stakeholders to enhance data-driven decision-making and mentor teams in analytics engineerin...
Today
$86K *
Shape the future of behavioral health by leading assessments and support plans for individuals with dual diagnoses. Collaborate with a dedicated team to enhance adaptive behaviors and ensure effective...
2 weeks ago
$115K - $130K *
Join a dynamic team as you provide essential IT support to a distributed workforce. Leverage your troubleshooting skills to resolve technical issues, enhance user experience, and contribute to a colla...
Reposted 1 week ago
$110K - $130K *
Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...
Reposted 2 weeks ago
Forward Deployed Process Consultant- R37
$113K - $226K *
Lead the charge in optimizing healthcare processes by bridging strategy and execution. Collaborate with teams to enhance coding workflows, drive change management, and ensure alignment with strategic...
3 weeks ago
Senior Product Analyst - Employer Health Solutions
$79K - $125K *
Lead the charge in enhancing Employer Health Solutions products, driving market competitiveness through collaboration, strategic analysis, and innovative development. Support regulatory compliance and...
Reposted 1 week ago
Senior Compliance Analyst-Advisory Services
$95K - $115K *
Drive compliance excellence by enhancing oversight procedures and controls. Collaborate with stakeholders to streamline processes, conduct data quality assessments, and ensure adherence to regulatory...
1 week ago
$110K - $130K *
Drive innovative solutions by leveraging data analytics and strategic counsel to enhance client performance. Collaborate with high-performing teams to deliver tailored insights for transformational ev...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.