Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Clinical Dietitian, Acute Care
$63K - $104K *
Join a team that's dedicated to providing exceptional clinical nutrition care. You'll conduct assessments, develop individualized interventions, and collaborate with healthcare professionals to enhanc...
4 weeks ago
Associate Director, Product (Data)
$165K - $175K *
Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...
4 weeks ago
Sr. Subservicing Oversight Analyst
$80K - $95K *
Transform client relationships by managing subservicing deliverables, ensuring compliance, and enhancing reporting processes. Collaborate with vendors and internal teams to support client needs and dr...
Today
$80K - $95K *
Elevate patient care by leading nursing teams, developing policies, and ensuring compliance. Drive operational efficiency and foster a supportive environment while collaborating with interdisciplinary...
3 weeks ago
Manager, Clinical Data Management Study Lead
$114K - $187K *
Optimize clinical data management processes by leading teams and ensuring compliance with standards. Collaborate with stakeholders to enhance data quality and streamline operations across multiple com...
1 week ago
$95K - $115K *
Join a team that's dedicated to enhancing ERP solutions for colleges and universities. As a consultant, you'll collaborate on Ellucian Banner implementations, ensuring client needs are met within scop...
Reposted today
Senior Marketing Operations Analyst
$106K - $141K *
Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...
2 weeks ago
Software Engineer - Data Platform (R37)
$105K - $202K *
Engineer robust data platforms by designing scalable pipelines and APIs that support AI-driven healthcare applications, ensuring high performance, security, and operational excellence in a collaborati...
Reposted yesterday
Associate Director, Analytical Development
$185K - $215K *
Take ownership of analytical development initiatives, ensuring compliance, accuracy, and high-quality documentation for multiple projects. Collaborate closely with internal teams and external partners...
Reposted today
Director of Market Development & Referral Strategy
$110K - $130K *
Lead the charge in developing referral growth and market strategies across multiple states. Drive sustainable growth by optimizing processes, leveraging CRM systems, and building high-performing teams...
1 week ago
Partner Manager, AI Ecosystems
$140K - $175K *
Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...
Reposted 3 weeks ago
$100K - $120K *
Transform oral healthcare by providing comprehensive dental services, diagnosing conditions, and developing treatment plans. Collaborate with a dedicated team to enhance patient outcomes and serve und...
1 week ago
ServiceNow ITOM Business Analyst
$130K - $140K *
Shape the future of IT operations by bridging infrastructure and development teams. Utilize your expertise in ServiceNow ITOM to analyze requirements, streamline processes, and enhance operational eff...
4 weeks ago
Senior Administrator, Systems Management
$110K - $130K *
Transform endpoint management by designing and deploying solutions across a vast device estate. Collaborate with cross-functional teams to ensure security, compliance, and reliability while leveraging...
4 weeks ago
Shareholder Services Lead - Hybrid
$118K - $196K *
Transform employee equity and shareholder services by leading stock plan operations, ensuring compliance and accuracy while collaborating with cross-functional teams to enhance processes and support s...
6 days ago
$100K - $110K *
Elevate the impact of early childhood development by managing and expanding the HELP product suite. Drive customer relationships, account growth, and new business development while supporting practiti...
1 week ago
Leader, Solutions Engineer, Splunk
$209K - $275K *
Elevate your career by leading and developing a high-performing Solutions Engineering team. Drive strategic alignment across functions, foster technical excellence, and implement innovative practices...
Reposted 2 weeks ago
$100K - $110K *
Drive valuable insights by enhancing Anaplan models and dashboards, collaborating with teams to implement solutions and improve functionality, while supporting users throughout the development lifecyc...
Reposted 1 week ago
Behavioral Health Virtual Preceptor - Nurse Practitioner or Physician Assistant
$100K - $120K *
Unlock potential by mentoring new providers through virtual education, ensuring a seamless onboarding experience. Leverage your clinical expertise to foster growth in both primary care and behavioral...
3 weeks ago
Nurse Practitioner or Physician Assistant - F/T - Bridgeton Internal Medicine
$95K - $125K *
Unlock potential by joining a collaborative team focused on delivering comprehensive primary care. Engage with patients in an outpatient setting, emphasizing preventive care and wellness while working...
6 days ago
Regulatory Policy and Intelligence Associate Director
$155K - $210K *
Shape the future of regulatory policy by leading initiatives that influence key decisions and drive alignment across teams. Collaborate with stakeholders to advocate for impactful policies that suppor...
5 days ago
$191K - $305K *
Champion innovative healthcare solutions by leveraging clinical expertise to enhance value-based strategies, drive operational excellence, and foster strategic partnerships for improved member care an...
4 weeks ago
$160K - $200K *
Support a dynamic team providing exceptional anesthesia care in a collaborative outpatient GI setting. Enjoy a predictable schedule with no call responsibilities, leveraging your skills in a modern, a...
Reposted today
Manager, Client Delivery - Insurance Discovery
$65K - $116K *
Engage with clients to ensure seamless delivery of Insurance Discovery services, managing relationships and expectations while coordinating with internal teams for successful implementation and ongoin...
Yesterday
Manager, Applications, Epic Orders
$165K - $264K *
Pioneer cross-functional collaboration to manage IS projects, ensuring successful implementation and support of applications, upgrades, and integrations while overseeing budgets and resources across S...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.