Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$115K - $125K *
Unlock potential by developing financial models and analytics to support pricing strategies. Collaborate with attorneys to enhance profitability through innovative pricing arrangements and comprehensi...
6 days ago
$101K - $146K *
Unlock potential by leading payer contract negotiations to enhance relationships, optimize revenue, and ensure compliance with regulations, all while aligning with strategic priorities of the health s...
3 weeks ago
Director Field Clinical & Patient Screening Programs
$149K - $298K *
Lead strategic and operational initiatives for field clinical teams, ensuring compliance and effective trial support for TMVR programs while driving positive patient outcomes and team performance...
2 weeks ago
General Manager, Healthcare Practices
$275K - $325K *
Drive the growth of healthcare practices by owning strategy, partnerships, and P&L. Collaborate with teams to deliver tailored financial solutions, while leveraging your network to establish Flex as t...
6 days ago
$86K - $138K *
Drive independent assessments of deployment readiness across workstreams, ensuring quality and compliance. Collaborate with teams to produce readiness evaluations and present findings to leadership, e...
1 week ago
Senior Associate, Strategy & Operations
$125K - $155K *
Champion strategic initiatives by connecting breakthrough chemistry with market opportunities. Collaborate across teams to drive government partnerships, proposals, and commercial growth, transforming...
3 weeks ago
$100K - $120K *
Lead the charge in transforming IT support for healthcare centers by evaluating, planning, and executing transitions to AMSURG Managed IT Services, while architecting cloud solutions with Microsoft 36...
3 weeks ago
$115K - $150K *
Lead strategic pricing initiatives by developing complex cost models and ensuring compliance with federal regulations. Collaborate across departments to create competitive proposals that drive busines...
1 week ago
Infection Preventionist-Licensed
$80K - $80K *
Serve as a key resource in infection prevention, utilizing clinical expertise to enhance patient outcomes through data analysis, education, and performance improvement initiatives within the healthcar...
4 days ago
Senior Sales Executive, Strategic Banking
$130K - $160K *
Lead strategic banking initiatives by leveraging your enterprise sales expertise to build relationships and drive new business within Tier 1 global banks, shaping our go-to-market strategy and establi...
4 days ago
Associate Director Government Pricing
$140K - $180K *
Join our team to enhance government pricing accuracy and compliance. This role supports strategic oversight across cross-functional teams, ensuring timely reporting and operational excellence in gover...
Reposted 2 weeks ago
Clinical Dietitian, Acute Care
$63K - $104K *
Join a team that's dedicated to providing exceptional clinical nutrition care. You'll conduct assessments, develop individualized interventions, and collaborate with healthcare professionals to enhanc...
4 weeks ago
Associate Director, Product (Data)
$165K - $175K *
Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...
4 weeks ago
Sr. Subservicing Oversight Analyst
$80K - $95K *
Transform client relationships by managing subservicing deliverables, ensuring compliance, and enhancing reporting processes. Collaborate with vendors and internal teams to support client needs and dr...
Today
$80K - $95K *
Elevate patient care by leading nursing teams, developing policies, and ensuring compliance. Drive operational efficiency and foster a supportive environment while collaborating with interdisciplinary...
3 weeks ago
Manager, Clinical Data Management Study Lead
$114K - $187K *
Optimize clinical data management processes by leading teams and ensuring compliance with standards. Collaborate with stakeholders to enhance data quality and streamline operations across multiple com...
1 week ago
$95K - $115K *
Join a team that's dedicated to enhancing ERP solutions for colleges and universities. As a consultant, you'll collaborate on Ellucian Banner implementations, ensuring client needs are met within scop...
Reposted today
Senior Marketing Operations Analyst
$106K - $141K *
Join a team that's building an AI-ready data foundation for marketing and GTM. You'll design, govern, and analyze data models, ensuring reliable insights for strategic decision-making across the organ...
2 weeks ago
Software Engineer - Data Platform (R37)
$105K - $202K *
Engineer robust data platforms by designing scalable pipelines and APIs that support AI-driven healthcare applications, ensuring high performance, security, and operational excellence in a collaborati...
Reposted yesterday
Associate Director, Analytical Development
$185K - $215K *
Take ownership of analytical development initiatives, ensuring compliance, accuracy, and high-quality documentation for multiple projects. Collaborate closely with internal teams and external partners...
Reposted today
Director of Market Development & Referral Strategy
$110K - $130K *
Lead the charge in developing referral growth and market strategies across multiple states. Drive sustainable growth by optimizing processes, leveraging CRM systems, and building high-performing teams...
1 week ago
Partner Manager, AI Ecosystems
$140K - $175K *
Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...
Reposted 3 weeks ago
$100K - $120K *
Transform oral healthcare by providing comprehensive dental services, diagnosing conditions, and developing treatment plans. Collaborate with a dedicated team to enhance patient outcomes and serve und...
1 week ago
ServiceNow ITOM Business Analyst
$130K - $140K *
Shape the future of IT operations by bridging infrastructure and development teams. Utilize your expertise in ServiceNow ITOM to analyze requirements, streamline processes, and enhance operational eff...
3 weeks ago
Senior Administrator, Systems Management
$110K - $130K *
Transform endpoint management by designing and deploying solutions across a vast device estate. Collaborate with cross-functional teams to ensure security, compliance, and reliability while leveraging...
4 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.