Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Manager, Patient Accounts - Hospital Patient Accounts - Billing Follow Ups and Denials - Days
$73K - $119K *
Drive revenue cycle improvements by managing claims follow-up and denials. Leverage expertise in billing processes to enhance financial performance and establish partnerships with payors for timely re...
2 days ago
$80K - $95K *
Analyze complex model development and validation projects, leveraging your statistical expertise to drive performance management. Collaborate with senior managers and progress to a subject matter expe...
1 week ago
$80K - $95K *
Champion complex model development and validation across diverse projects. Leverage your statistical expertise to enhance performance management while collaborating with senior leaders and progressing...
1 week ago
Complex Claims Advisor | Dedicated Client | East Coast States
$90K - $100K *
Unlock potential by managing complex claims with a focus on legal inquiries and resolutions. Collaborate with clients and experts to deliver innovative solutions while enjoying flexibility and profess...
2 weeks ago
Manager, Utilization Management
$87K - $161K *
Lead the charge in managing a clinical review team to ensure optimal member care through effective utilization management and compliance with healthcare standards. Drive improvements and foster commun...
4 days ago
Senior Attack Engineer, External
$206K - $242K *
Transform external attack capabilities by developing scalable workflows and automating reconnaissance processes. Drive innovation in offensive security, mentor teammates, and contribute to a high-impa...
2 weeks ago
Associate Clinical Oncology Specialist
$80K - $100K *
Join a dynamic team as you enhance patient outcomes in Oncology. Contribute to sales and support activities, build key relationships, and optimize clinical workflows while driving patient retention an...
2 days ago
Senior Strategic Solutions Architect
$175K - $205K *
Transform the future of client technology by leading architectural strategies and integrations in life insurance and annuity environments, ensuring alignment with enterprise goals and delivering scala...
Reposted today
All-Source Intelligence Analyst
$80K - $95K *
Unlock potential by conducting critical analysis on transnational threats, fusing multi-source intelligence, and producing actionable insights to enhance border security and inform strategic decision...
1 week ago
Vice President, Regulatory Strategy Diligence
$285K - $385K *
Lead regulatory due diligence for clinical/commercial assets, assessing risks and strategies for licensing, acquisitions, and partnerships. Collaborate across teams to ensure regulatory integration in...
5 days ago
Nurse Practitioner Palliative Care
$95K - $115K *
Transform patient care by delivering advanced palliative services in home settings. Collaborate with an interdisciplinary team to enhance quality of life for patients facing complex medical challenges...
Today
Nurse Practitioner Palliative Care
$95K - $115K *
Empower patients by delivering advanced palliative care in their homes, collaborating with an interdisciplinary team to enhance quality of life while managing complex medical needs and guiding familie...
Today
Nurse Practitioner Palliative Care
$95K - $115K *
Join a dedicated team as you provide advanced palliative care, enhancing patients' quality of life while managing complex medical needs. Collaborate with healthcare professionals to deliver compassion...
1 week ago
Director I, Data Science, Enterprise Data & Data Science
$138K - $165K *
Unlock potential by leveraging your data science expertise to innovate generative AI solutions. Lead cross-functional collaborations, build evaluation frameworks, and drive best practices within a dyn...
Reposted 5 days ago
$130K - $155K *
Elevate your career by designing and training advanced machine learning models. Collaborate with experts to analyze data, create reinforcement learning environments, and communicate findings effective...
Today
Variable Compensation Systems Analyst
$100K - $120K *
Lead the management of variable compensation systems, ensuring accurate calculations and data integrity. Drive automation and provide mentorship to enhance team capabilities while collaborating across...
1 week ago
Associate Vice President, Interoperability Strategy, Operations & Partnerships
$160K - $200K *
Lead the charge in shaping healthcare interoperability by architecting and operationalizing comprehensive data exchange capabilities. Drive transformation through strategic partnerships and a high-per...
Yesterday
Senior Financial Analyst, Treasury
$99K - $132K *
Advance your career as a Senior Financial Analyst in Treasury, focusing on cash management, corporate finance, and cross-functional collaboration. Drive impactful financial strategies while enhancing...
2 weeks ago
Senior Product Analyst, Coverage & Forms
$82K - $102K *
Shape the future of pet insurance by developing and enhancing policy forms, ensuring compliance, and collaborating with cross-functional teams to meet customer needs and regulatory standards...
3 weeks ago
Environmental Underwriting Specialist
$130K - $180K *
Join a team that's dedicated to expanding our Environmental Impairment Liability book. Leverage your underwriting expertise to drive growth, mentor junior staff, and collaborate across departments to...
2 weeks ago
$130K - $160K *
Deliver high-quality telemedicine care to complex patients, focusing on symptom management and improving outcomes. Collaborate with a multidisciplinary team to enhance patient experiences and facilita...
Today
$100K - $120K *
Champion oral health excellence by diagnosing and treating patients' dental needs, supervising procedures, and educating the community, while leading a dedicated team in a supportive healthcare enviro...
Reposted 4 days ago
Director, NDD Business Development: Neurology Clinics
$162K - $224K *
Drive growth in the Neurodegenerative Disease sector by developing strategic partnerships with health systems and academic centers, leveraging existing relationships to create innovative solutions tha...
2 weeks ago
Patient and Site Engagement Lead (US/UK)
$90K - $178K *
Transform the patient engagement landscape in clinical trials by developing and delivering strategic support initiatives. Partner with diverse stakeholders to enhance participation and optimize patien...
Reposted 1 week ago
Dir/Sr Dir, Strategy & Delivery (Gen Med - Rare Disease - US and/or Canada)
$134K - $306K *
Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.