Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Account Executive, Government & Public Sector
$105K - $140K *
Transform your career by leading government sales efforts in a high-growth environment. Leverage your expertise to build relationships, create pipelines, and drive revenue for a cutting-edge product i...
2 weeks ago
Lifecycle Acquisition Analyst - Senior
$140K - $175K *
Optimize acquisition management for complex government programs, ensuring compliance and mission success. Lead requirement validation, procurement package development, and contract execution monitorin...
Reposted 1 week ago
$80K - $100K *
Join a team that's driving financial insights and pricing strategies to enhance profitability. Collaborate with cross-functional teams to support client proposals and contract renewals while navigatin...
Reposted 3 days ago
$128K - $192K *
Unlock potential by driving new business growth through actionable health intelligence. Build relationships, identify client needs, and showcase solutions to enhance employee wellbeing and manage heal...
6 days ago
VP, Client Services (Access Marketing)
$150K - $180K *
Join a team that's redefining client success in the pharma sector by leading strategic initiatives, fostering senior-level relationships, and driving innovative marketing solutions for key accounts wh...
4 days ago
$160K - $190K *
Elevate healthcare solutions by transforming complex data needs into scalable systems. Collaborate with cross-functional teams to design and build data pipelines and insightful dashboards that enhance...
Reposted 3 weeks ago
Director, Healthcare - Construction
$120K - $150K *
Inspire excellence in healthcare project delivery by leading a dynamic team, ensuring compliance, and driving innovation. Oversee strategic initiatives, manage client relationships, and foster a cultu...
Reposted 4 days ago
Licensed Therapist (LCSW, LPC, LMFT)
$80K - $101K *
Transform patient care by joining our dedicated team of Licensed Therapists. Enjoy flexible schedules, competitive compensation, and a supportive environment focused on outpatient services and work/li...
Yesterday
Licensed Therapist (LCSW, LPC, LMFT)
$80K - $101K *
Join a team that's dedicated to transforming patient care through flexible, outpatient therapy. Enjoy competitive compensation, autonomy in scheduling, and a supportive environment focused on work/lif...
Yesterday
Licensed Therapist (LCSW, LPC, LMFT)
$80K - $101K *
Engage with a dynamic clinical team to provide exceptional outpatient therapy. Enjoy flexible scheduling, competitive compensation, and a supportive environment focused on patient care and work/life b...
Yesterday
Principal RAS Partner & Educator
$98K - $132K *
Transform healthcare by leading Risk Adjustment strategies and educational initiatives. Collaborate with teams to enhance coding accuracy and documentation, ensuring compliance and delivering impactfu...
1 week ago
Mobile Licensed Nursing Home Administrator
$80K - $95K *
Deliver exceptional leadership as an interim Nursing Home Administrator, ensuring compliance and quality care across multiple facilities. Drive operational excellence, mentor teams, and enhance reside...
5 days ago
$90K - $110K *
Join a team that's dedicated to delivering compassionate hospice care. As a key member, you'll assess patient needs, provide palliative support, and collaborate with healthcare professionals to enhanc...
2 weeks ago
Business Analytics Engineer, Customer Insights
$100K - $120K *
Lead the charge in transforming healthcare analytics by building robust data models and dashboards. Collaborate with diverse stakeholders to deliver actionable insights, ensuring data quality and clar...
2 weeks ago
Transitions of Care RN Case Manager
$85K - $100K *
Elevate patient care by providing telephonic case management for high-risk individuals post-discharge. Advocate for patients, coordinate resources, and develop personalized care plans to enhance healt...
2 days ago
RN (Registered Nurse) Home Health Case Manager
$80K - $95K *
Champion patient care by managing caseloads, collaborating with teams, and ensuring compliance. Utilize nursing expertise to educate patients and enhance quality of life in a dynamic home health envir...
1 week ago
$70K - $100K *
Join a team that's committed to financial excellence, ensuring accuracy and compliance in accounting operations. Lead month-end closes, enhance reporting, and drive process improvements while mentorin...
1 week ago
Senior Director, Business Development
$150K - $180K *
Join a team that's driving growth in the biopharmaceutical sector by developing strategic business relationships, prospecting new clients, and leading sales initiatives to achieve organizational objec...
1 week ago
$227K - $341K *
Lead the strategic development and continuous improvement of clinical programs, focusing on optimizing patient care across the continuum. Oversee a multidisciplinary team to enhance outcomes, reduce h...
1 week ago
$80K - $95K *
Optimize data management processes for large government acquisitions, ensuring effective communication between teams and shipyards. Lead document management, maintain schedules, and enhance data quali...
6 days ago
Health Provider Revenue Cycle Manager
$87K - $293K *
Help us lead transformative revenue cycle projects for complex healthcare organizations, optimizing patient access, mid-cycle, and back-end operations while driving measurable improvements and fosteri...
Reposted today
Associate Medical Director, Clinical Research
$225K - $281K *
Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...
Reposted 3 days ago
Nurse Practitioner- Hospice (Savannah, MO)
$95K - $143K *
Champion compassionate care by assessing patient needs and managing symptoms in a collaborative hospice team. Engage with families to enhance quality of life during end-of-life care, ensuring dignity...
Today
Associate Director, MSL, CMH Cleveland
$156K - $250K *
Champion scientific exchange by leveraging deep expertise to engage with key opinion leaders, providing critical insights and fostering collaborations that shape the future of healthcare and enhance p...
Yesterday
$88K - $105K *
Lead women's health services by overseeing operations, ensuring quality care, and fostering collaboration among teams. Drive strategic initiatives, enhance patient safety, and promote staff developmen...
2 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.