Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$100K - $120K *
Elevate operational efficiency by managing account priorities and delivering proactive business solutions. Collaborate with teams to ensure high-quality service and maintain strong relationships with...
4 weeks ago
$125K - $150K *
Lead the development of AI-driven data solutions to optimize business operations. Collaborate with stakeholders to enhance digital transformation initiatives in underwriting and claims functions, driv...
Reposted 3 days ago
Clinical Data Manager - REDCap/CTDB
$95K - $115K *
Unlock your potential by managing clinical data for impactful research. Collaborate with multidisciplinary teams to design databases, ensure compliance, and deliver high-quality data management soluti...
Today
Behavioral Health Medical Director
$223K - $313K *
Shape the future of behavioral health care strategy and operations. Leverage your medical expertise to enhance quality, operational efficiency, and patient outcomes while navigating complex regulatory...
Reposted 6 days ago
Director of Client Success - Revenue Cycle Management - (MIDWEST)
$110K - $130K *
Drive client success by managing relationships, enhancing satisfaction, and identifying growth opportunities. Collaborate with internal teams to deliver exceptional service and exceed client expectati...
1 week ago
$84K - $87K *
Join us as a Data Operations Engineer, where you'll develop and manage data systems for healthcare claims processing. Collaborate with teams to ensure data accuracy and optimize ETL/ELT pipelines whil...
Reposted 3 weeks ago
$93K - $108K *
Empower patients by delivering exceptional occupational therapy services. Collaborate with a dedicated team to enhance patient outcomes in a supportive environment. Ideal for both experienced professi...
4 weeks ago
$150K - $200K *
Lead client engagements by leveraging tax expertise to drive revenue growth, manage complex planning discussions, and enhance client relationships while ensuring strategic alignment across teams for o...
1 week ago
$90K - $95K *
Join a team that's shaping the future of pricing strategy by developing financial models, analyzing data, and collaborating with partners to enhance profitability and efficiency in a dynamic environme...
5 days ago
Senior Vice President, Payer Sales
$225K - $250K *
Elevate your career by leading payer sales strategy and team development, driving new business opportunities in healthcare technology. Collaborate with executives to enhance performance and deliver im...
3 weeks ago
Physical Therapist Home Health
$80K - $95K *
Elevate patient care by developing tailored rehabilitation plans, performing evaluations, and delivering effective treatments. Collaborate with a dedicated team to enhance patient outcomes and ensure...
2 weeks ago
Principal Sales Solutions Consultant
$160K - $195K *
Engage with healthcare payer clients to architect integrated solutions, driving revenue growth through strategic discovery, technical leadership, and value engineering. Collaborate across teams to del...
1 week ago
$50K - $114K *
Transform financial operations by driving budgeting, forecasting, and reporting processes. Collaborate with stakeholders to ensure accuracy and alignment in workforce planning, while supporting leader...
Reposted today
$138K - $198K *
Innovate financial strategies as a key partner in FP&A, driving insights and accountability across R&D and G&A. Own financial models, forecasts, and planning processes to support strategic decision-ma...
3 weeks ago
$110K - $130K *
Transform healthcare by building scientific relationships and providing objective, compliant information to key stakeholders, enhancing clinical practice and patient outcomes through expert knowledge...
3 weeks ago
Technology Support Analyst – Identity Management
$83K - $109K *
Drive user identity management and access governance, ensuring secure, timely access to technology resources. Collaborate with HR and IT teams to enhance employee experience while maintaining complian...
2 days ago
Medical Writer, Medical Communications
$80K - $110K *
Join a team that's dedicated to transforming complex scientific data into clear, impactful content. Collaborate with peers to ensure accuracy and adherence to guidelines while developing crucial mater...
Reposted 3 weeks ago
Data Engineer | VA Claims Modernization
$120K - $180K *
Drive the modernization of Veterans Benefits Administration claims processing by designing and optimizing scalable data pipelines and solutions, ensuring efficient data integration and analytics for i...
1 week ago
Clinical Account Executive (RPh) - Archimedes
$100K - $120K *
Bring your expertise to a dynamic role as a Clinical Account Executive, where you'll lead specialty medication management, collaborate with healthcare professionals, and drive formulary development to...
Today
$92K - $138K *
Join our team to lead the Virtual Utilization Management Program, ensuring clinical excellence and operational efficiency. Collaborate with diverse healthcare professionals to enhance patient care and...
4 weeks ago
$80K - $95K *
Transform your sales career by engaging mid-sized businesses with cutting-edge insights. Drive data-driven decisions and close deals while leveraging innovative tools in a dynamic, supportive environm...
Today
Associate, Corporate Development
$115K - $140K *
Drive impactful growth by mapping industrial markets, evaluating acquisition targets, and building investment models. Collaborate on live transactions to shape strategic decisions that enhance manufac...
3 weeks ago
$85K - $90K *
Champion strategic leadership in employee benefits and leave programs, ensuring compliance and operational excellence. Lead a dedicated team to enhance service delivery and employee experience while m...
Today
$95K - $115K *
Unlock potential by leading bioanalytical projects, designing assays, managing teams, and ensuring quality compliance. You will drive drug development through scientific expertise in bioanalytical met...
Reposted 4 days ago
Senior Total Rewards & HR Analytics Specialist - Remote
$103K - $193K *
Unlock potential by enhancing compensation programs and delivering insightful HR analytics. Collaborate with cross-functional teams to ensure equitable, compliant, and data-driven total rewards practi...
2 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.