Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$90K - $110K *

Shape the future of consumer lending by analyzing credit risk and performance data to drive strategic insights for financial institutions, optimizing their underwriting processes and enhancing portfol...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$75K - $105K *

Optimize mainframe systems as a key analyst, ensuring stability and performance of IBM z/OS environments. Collaborate with teams to troubleshoot issues and maintain critical applications, while enhanc...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $112K *

Elevate your career by providing advanced governance, risk, and compliance support for federal information systems, ensuring compliance with federal laws and regulations while engaging with key stakeh...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$212K - $409K *

Drive innovation as a key member of our engineering team, leveraging your expertise in software engineering and data platforms to shape solutions that enhance customer experiences and meet business go...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$115K - $150K *

Engage in strategic corporate partnerships to drive revenue growth and mission impact. Lead a team in cultivating executive relationships, securing multi-million dollar partnerships, and implementing...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$132K - $165K *

Drive innovation in oncology diagnostics by leading statistical programming efforts, ensuring data integrity and compliance for clinical trials, while managing a team and collaborating cross-functiona...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive strategic oversight of enterprise-wide RAC audit activities, ensuring compliance and operational excellence. Collaborate with leadership to enhance audit processes, minimize financial risk, and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $106K *

Optimize IT service delivery by managing configuration items, analyzing operational data, and ensuring effective incident resolution. Collaborate with cross-functional teams to enhance service perform...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$95K - $115K *

Empower patient care by joining a collaborative team focused on pediatric neurology. This role offers a supportive environment for both seasoned professionals and those early in their careers, ensurin...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower your career by driving financial insights and analytics. Collaborate across teams to transform data into strategic decisions, enhancing growth and efficiency in a dynamic environment. Join us...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's redefining report development for public safety platforms. Design and implement dynamic reports leveraging .NET technologies to provide insights that enhance operational decision-ma...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Information Technology

$85K - $120K *

Drive security excellence by leveraging technical skills to protect government organizations from advanced threats. Engage in real-time incident response, monitoring, and analysis within a compliance...

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Transform patient care by collaborating with a dedicated team of physicians and advanced practitioners in a dynamic hospital setting, focusing on quality and comprehensive gastroenterology services fo...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $155K *

Empower clients by analyzing data to drive strategic improvements and enhance engagement. Collaborate with teams to develop innovative solutions, support project management, and foster relationships t...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$80K - $135K *

Empower communities by leading strategic initiatives in homelessness services. Utilize your expertise to enhance organizational capacity, improve service coordination, and drive sustainable solutions...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$88K - $154K *

Transform your career by leading full-lifecycle recruiting for federal proposals, focusing on defense and intelligence sectors. Collaborate with teams to develop strategies, source talent, and ensure...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$100K - $120K *

Transform federal contract administration by providing expert guidance and support throughout the acquisition lifecycle, ensuring compliance and efficiency while collaborating with cross-functional te...

Today

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Drive the deployment of healthcare technology across multiple VA facilities, coordinating projects and ensuring readiness. Collaborate with diverse teams to manage timelines, resolve issues, and deliv...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Transform patient care by providing comprehensive primary services in a supportive, collaborative environment. Enjoy flexible scheduling with no nights or weekends while focusing on preventive care an...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$113K - $142K *

Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Manage acute and chronic patient care in specialty services, performing assessments and developing treatment plans in both ambulatory and hospital settings, while collaborating with physicians to ensu...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$89K - $113K *

Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead a dynamic SOC team as a Senior Cybersecurity Analyst, enhancing threat detection and incident response through AI and machine learning. Drive security improvements and mentor team members while s...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.