Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Provider Clinical Operations Consultant, Senior Associate
$77K - $202K *
Drive clinical operations modernization for healthcare providers, enhancing efficiency and service delivery. Analyze complex challenges, mentor junior staff, and foster client relationships while navi...
Today
$102K - $179K *
Unlock potential by designing and developing innovative software solutions that drive business objectives. Collaborate with cross-functional teams to tackle complex challenges and mentor engineers in...
4 weeks ago
Sr. Director, Industry and Payor Strategy
$174K - $217K *
Drive strategic leadership in industry partnerships and payor strategy, enhancing market access and competitive positioning. Lead a high-performing team to execute a multiyear plan that fosters sustai...
1 week ago
Second Level Reviewer-Clinical Documentation Integrity
$89K - $148K *
Champion clinical excellence by conducting thorough chart reviews, ensuring documentation accuracy, and collaborating with healthcare teams to enhance patient care standards and compliance with regula...
2 days ago
Insurance Industry & Function AI Decision Science Consultant
$70K - $205K *
Drive innovative AI solutions in the Insurance sector by leveraging advanced analytics and machine learning. Collaborate with diverse teams to enhance decision-making processes and deliver impactful r...
1 week ago
Enterprise Account Executive - Healthcare
$240K - $330K *
Pioneer growth in the healthcare sector by driving new business and cultivating strong client relationships. Utilize expert sales skills to oversee complex deals from prospecting to closing in a consu...
Reposted 5 days ago
Finance Partner Senior, Geisinger Health Plan (Eastern Standard Time Zone resident)
$95K - $115K *
Transform financial operations by providing strategic support to business units, leading forecasting, and enhancing financial performance through collaboration and mentorship. Drive initiatives that p...
1 week ago
Senior Business Process Consultant
$87K - $157K *
Innovate cross-functional initiatives to enhance business processes, drive performance improvements, and ensure strategic alignment. Collaborate with diverse teams to optimize operations and deliver i...
Reposted today
$69K - $104K *
Unlock your potential by collaborating with leaders to enhance payor performance, streamline revenue cycle operations, and drive innovation in healthcare. Your expertise will ensure impactful engageme...
5 days ago
Supervising Physician - Dermatology (Remote)
$210K - $250K *
Lead the charge in providing remote clinical oversight for Dermatology PAs, ensuring high-quality patient care and compliance with regulations. Collaborate with a dedicated team to foster clinical exc...
2 weeks ago
Senior Clinical Research Associate, Northwestern regions, USA
$95K - $115K *
Elevate clinical research by monitoring trials, ensuring compliance with protocols and regulations. Collaborate with investigators to achieve study goals in dermatology and rheumatology, while working...
1 week ago
Enterprise Customer Success Manager
$110K - $130K *
Build lasting relationships and drive customer success by leveraging insights and data to enhance client engagement and retention. Collaborate cross-functionally to inform product improvements and sup...
3 weeks ago
Oncology Nurse Case Manager - Remote
$77K - $129K *
Transform healthcare delivery by partnering with customers to create personalized care plans, ensuring effective navigation through the healthcare system while collaborating with interdisciplinary tea...
Reposted today
$166K - $200K *
Help us deliver exceptional primary care services to Veterans by providing comprehensive clinical practice, consultation, and management within a collaborative healthcare team, ensuring quality and ti...
Today
Business Development Manager - Healthcare
$100K - $120K *
Join a team that's transforming healthcare by driving sales of innovative water purification systems. Leverage your expertise to build relationships and ensure compliance, enhancing patient safety acr...
1 month ago
Senior Analyst, ALM & Treasury
$88K - $141K *
Empower financial strategies by analyzing interest rate and liquidity risks. Collaborate with stakeholders to enhance capital planning and reporting processes while ensuring compliance with regulation...
1 week ago
Technical Account Manager - Healthcare
$95K - $115K *
Drive the technical relationship with healthcare accounts, ensuring platform adoption, risk mitigation, and customer growth through proactive advisory and strategic planning. Collaborate with IT teams...
2 weeks ago
Senior Financial Analyst, FP&A (R&D)
$111K - $167K *
Transform financial operations by driving monthly close processes, managing forecasts, and leveraging AI for process improvements while serving as a key business partner to leadership to enhance strat...
Reposted 1 week ago
$133K - $180K *
Join a team that's redefining member experiences by architecting optimal journeys, bridging operational execution with strategic vision to enhance engagement and satisfaction across all touchpoints...
Reposted 1 week ago
$93K - $109K *
Support the execution of strategic priorities by analyzing data, developing reports, and coordinating initiatives. Collaborate with leaders to identify trends and enhance planning processes, ensuring...
Yesterday
Staff Product Manager, Longitudinal Patient Record
$188K - $245K *
Advance our longitudinal patient record by leading product strategy, ensuring data integrity, and enhancing clinical utility. Collaborate with cross-functional teams to deliver a unified view of patie...
Yesterday
Salesforce Senior Business Analyst
$110K - $150K *
Empower your career by leading client engagements and analysis within our dynamic Salesforce practice. Collaborate with a supportive team to deliver innovative solutions that address current challenge...
Reposted 1 week ago
$112K - $132K *
Join a team that's shaping the future of autism care by building robust statistical methodologies. You'll analyze real-world clinical data, ensuring rigorous evaluation of outcomes and social validity...
1 week ago
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Elevate your career by leading innovative Customer MDM and Data Governance initiatives in Life Sciences. Drive commercial transformation with AI-powered solutions, ensuring accurate data foundations f...
1 week ago
Life Sciences Data Management, Lead (MDM/DGov)
$134K - $265K *
Join a dynamic team to lead innovative Customer MDM and Data Governance solutions in Life Sciences, driving commercial transformation through AI-powered insights and trusted data management for enhanc...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.