Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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Healthcare Analyst Jobs in Missouri

Sort By: Relevance

$110K - $130K *

Champion data-driven decision-making by transforming insights into actionable reports and dashboards. Collaborate with cross-functional teams to enhance performance, optimize strategies, and drive bus...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$75K - $90K *

Unlock potential by leading data analysis and storytelling efforts, ensuring insights meet client needs. Collaborate with teams to deliver actionable reports and maintain high-quality standards throug...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$125K - $140K *

Optimize your career by managing enterprise-wide database environments, ensuring high availability, executing disaster recovery strategies, and supporting critical operations in a dynamic SaaS ecosyst...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $138K *

Empower your career by transforming demand into actionable workforce strategies. Lead capacity planning and vendor performance in a dynamic remote environment, ensuring optimal resource allocation and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $210K *

Explore innovative solutions as you lead the design and architecture of scalable healthcare applications, mentor engineers, and collaborate with cross-functional teams to enhance patient experiences a...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$87K - $253K *

Unlock potential by serving as a trusted advisor to C-suite executives, defining technology-driven business strategies that leverage AI and emerging technologies to enhance competitive advantage and o...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$80K - $95K *

Join a team that's driving growth in mid-market healthcare by building relationships, managing a dynamic sales pipeline, and closing new business opportunities in a fast-paced SaaS environment...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$140K - $175K *

Optimize data analytics support for lab production operations by leading a dedicated team in a dynamic environment. Drive innovation, ensure compliance, and enhance operational effectiveness while mak...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Elevate operational efficiency by providing high-level administrative support to senior leadership, coordinating meetings, managing correspondence, and ensuring compliance with Navy directives while f...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Business Services

$160K - $180K *

Champion growth and satisfaction by managing key Ecosystem client relationships. Drive sales of innovative data solutions in Life Sciences, leveraging deep industry knowledge to meet client needs and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Empower patients through comprehensive care in a supportive, collaborative environment. Join a dedicated team focused on preventive health and wellness, providing quality outpatient services with no n...

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$95K - $125K *

Lead comprehensive primary care services in a collaborative environment, focusing on adult patients. Manage acute and chronic conditions while emphasizing preventive care and patient education. Enjoy...

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$120K - $158K *

Champion operational excellence by leading facilities management across a multi-state portfolio. Drive strategic initiatives, optimize vendor performance, and implement scalable processes to support o...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$148K - $175K *

Unlock your potential as a Director, leveraging insights and expertise to guide clients in navigating complex SaaS negotiations and market trends, while driving impactful strategies that enhance busin...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$86K - $138K *

Lead actuarial initiatives by leveraging your expertise to analyze complex data, mentor junior staff, and develop innovative solutions that drive informed decision-making and enhance operational effic...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion high-quality, patient-centered care in the Emergency Department by providing strategic leadership and operational oversight. Drive quality improvement, ensure regulatory compliance, and foste...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Transform identity and access management by executing daily operations, supporting AI tooling, and managing SaaS vendor administration. This role offers hands-on experience and a clear growth path tow...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $110K *

Advance client partnerships by managing strategic initiatives, driving engagement, and optimizing healthcare solutions. Collaborate with internal teams to enhance service delivery and achieve clinical...

Missouri, USRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$145K - $160K *

Empower healthcare leaders by delivering actionable insights through advanced analytics. Collaborate with executives to address strategic workforce challenges, utilizing AI-driven data solutions to en...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Technical Services

$130K - $160K *

Drive the development of a semantic layer for a data and AI organization, defining key metrics and leading an analytics engineering team. Build core models and ensure definitional consistency across v...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$212K - $318K *

Drive the future of oncology evidence generation by leading global HEOR strategies, ensuring payer readiness, and optimizing clinical trial protocols to substantiate product value and support market a...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $120K *

Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $110K *

Drive accurate tax compliance and reporting for the Central Region, ensuring adherence to regulations and fostering relationships with stakeholders while leading audits and facilitating interdepartmen...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$78K - $206K *

Unlock potential by leading clinical performance improvement projects for Medicare Provider Collaboration groups. Collaborate with teams to enhance population health outcomes, focusing on Stars qualit...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.