Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
Senior Business Systems Analyst
$75K - $158K *
Drive enterprise-level technical solutions by analyzing system needs, coordinating design activities, and ensuring compliance with governance processes. Leverage your expertise to enhance performance...
Reposted 2 weeks ago
Client Growth & Success Principal Manager- Enterprise Accounts
$150K - $175K *
Shape the future of client partnerships by driving strategic growth and success for large enterprise organizations. Collaborate with cross-functional teams to deliver exceptional value and measurable...
2 weeks ago
$86K - $101K *
Unlock your potential by providing critical financial analyses and insights to drive strategic decision-making. Collaborate with management to enhance performance reporting and identify growth opportu...
5 days ago
Medical Review Nurse - CMS/RAC Auditor, Government Audits
$80K - $95K *
Join a team that's dedicated to enhancing healthcare quality through thorough medical claims audits. Leverage your nursing expertise in a dynamic remote environment, collaborating with experienced aud...
2 weeks ago
Regional Executive Director, Provider Sales - Southeast
$122K - $163K *
Elevate sales performance by leading a diverse team, driving strategic initiatives, and fostering customer relationships to achieve revenue growth and market penetration in a dynamic environment...
Yesterday
Certified Public Accountant (CPA) - Medicaid/Medicare
$100K - $120K *
Elevate your career by preparing and analyzing complex Medicaid cost reports, ensuring compliance with regulations, and leading a team of accountants in a remote setting. Drive process improvements an...
2 weeks ago
$80K - $110K *
Unlock potential by leading actuarial projects and analyses to help clients manage risks effectively. Collaborate with a dynamic team to apply advanced statistical methods and deliver insightful risk...
4 days ago
Senior Compliance Administrator - Enrollment, Billing, Finance, DIR
$87K - $157K *
Lead the execution of the Medicare Compliance Advisory program, ensuring adherence to CMS regulations. Collaborate with stakeholders to provide regulatory guidance, conduct audits, and enhance complia...
Reposted 1 week ago
Project Manager I - Integration/Government Sponsored Healthcare Programs
$62K - $100K *
Join a team that's dedicated to delivering successful projects by managing small complexity initiatives, ensuring milestones are met, and fostering collaboration across business and IT stakeholders fo...
Reposted 4 days ago
$80K - $95K *
Lead a dynamic team of travel therapy recruiters while driving personal production. Champion recruitment strategies, enhance team performance, and ensure alignment with client demands to achieve booki...
5 days ago
$69K - $119K *
Transform the landscape of clinical documentation by educating and mentoring teams, ensuring compliance, and enhancing documentation accuracy to optimize patient care and coding outcomes...
5 days ago
Clinical Pharmacist Specialist
$108K - $130K *
Empower patient care by delivering expert clinical pharmacy services, monitoring medication regimens, and collaborating with healthcare teams to enhance therapeutic outcomes in a dynamic hospital envi...
6 days ago
$72K - $97K *
Empower individuals by coordinating personalized care plans for seniors and members with disabilities. Collaborate with healthcare providers and manage caseloads while enjoying a flexible, remote work...
1 week ago
Healthcare Payment Solutions Consultant - Enterprise Market
$126K - $154K *
Transform healthcare payment solutions by driving business growth and optimizing client relationships. Leverage your expertise to develop tailored proposals and secure long-term partnerships with larg...
1 week ago
Actuary, Pricing - Individual MA
$129K - $177K *
Join a team that's shaping innovative pricing strategies for Medicare Advantage products. Collaborate cross-functionally to analyze market data, establish financial metrics, and drive profitable growt...
Reposted 1 week ago
$135K - $160K *
Lead a dynamic team to transform AI strategies into impactful healthcare solutions. Oversee engineering execution, guide architecture, and ensure compliance while collaborating with cross-functional p...
5 days ago
$96K - $132K *
Join a team that's dedicated to transforming healthcare through innovative solutions. Collaborate with clients and experts to implement cutting-edge products, ensuring optimal workflows and exceptiona...
3 days ago
Staff Biostatistician (Clinical Validation)
$164K - $205K *
Lead the design and analysis of clinical validation studies, ensuring regulatory compliance and driving innovative research in molecular diagnostics. Collaborate with cross-functional teams to enhance...
2 weeks ago
$95K - $115K *
Lead the charge in compliance initiatives, guiding teams and ensuring adherence to regulations while mentoring staff and driving awareness of compliance programs across the organization...
1 week ago
Vice President, Cost Management - Affordability
$144K - $180K *
Join a team that's redefining healthcare affordability by leading strategic initiatives to enhance cost management and improve quality outcomes across the organization. Collaborate with diverse teams...
Yesterday
Remote Behavioral Medical Director, Eastern Region
$215K - $408K *
Support the Chief Medical Director in directing medical management, quality improvement, and credentialing functions, ensuring effective utilization management and enhancing care quality for diverse p...
Today
Senior Analyst: Security Compliance & Assurance
$95K - $115K *
Join a team that drives security compliance and audit initiatives, ensuring adherence to industry standards. Provide oversight, validate controls, and empower stakeholders through transparency and eff...
Reposted today
Channel Development, Lead Retention
$115K - $158K *
Drive strategies to enhance customer engagement and retention for pharmacy services. Collaborate with cross-functional teams to optimize member experiences, increase auto-refill adoption, and boost pr...
Reposted 1 week ago
Remote Clinical Recruiter, Registered Dietitians
$85K - $95K *
Join a team that's redefining clinical recruitment by leading full-cycle hiring for Registered Dietitians. Drive innovative sourcing strategies and ensure a seamless candidate experience in a fast-pac...
4 days ago
Director, Operations Analytics & Workforce Strategy
$125K - $150K *
Join a dynamic team to drive operational excellence through data-driven strategies. Lead workforce planning, enhance performance metrics, and collaborate across functions to optimize patient services...
1 week ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.