Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$95K - $115K *
Transform enterprise processes by leading cross-functional improvement initiatives, mentoring analysts, and aligning strategies with organizational goals. Leverage Lean and Six Sigma expertise to driv...
3 weeks ago
$110K - $130K *
Engage in comprehensive pharmaceutical services, promoting safe medication therapy. Oversee the medication use system and collaborate with medical staff to ensure effective treatment and enhance patie...
Reposted yesterday
$100K - $125K *
Unlock your potential as a Revenue Compensation Analyst, where you'll design and manage compensation plans, analyze trends, and collaborate with teams to enhance sales efficiency. Bring your analytica...
2 weeks ago
Director, Client Coding Integration
$97K - $145K *
Join a dynamic team to lead physician coding integration initiatives, ensuring operational readiness and compliance. Collaborate across departments to enhance coding practices and drive revenue cycle...
6 days ago
Director, Client Coding Integration
$120K - $145K *
Execute accurate coding practices to ensure compliance and optimal reimbursement in a dynamic healthcare environment. Collaborate with clinical teams to maintain integrity and efficiency in revenue cy...
Reposted 2 weeks ago
$64K - $96K *
Join a team that's dedicated to providing exceptional home health care. As a Registered Nurse, you'll coordinate patient care, collaborate with healthcare professionals, and ensure quality service whi...
4 weeks ago
IT Clinical Informaticist - Dental Support
$71K - $99K *
Join a team that's dedicated to enhancing clinical practices through effective IT solutions. This role involves training, system maintenance, and collaboration with healthcare professionals to optimiz...
5 days ago
Senior Consultant - Financial Analyst
$100K - $130K *
Join a dynamic team as a Senior Consultant, leading municipal financial analyses and strategies. Drive impactful projects for local governments, enhancing service delivery and sustainability while dev...
2 weeks ago
Senior Data Analyst, Enterprise
$122K - $171K *
Unlock potential by driving data-driven insights for Customer Success. Collaborate across teams to enhance customer journeys, optimize growth strategies, and shape analytics foundations that support A...
Reposted today
$75K - $158K *
Empower your career by joining a dynamic team focused on enhancing IT operations. Leverage your expertise in Momentum Financials to drive impactful solutions and collaborate with stakeholders in a hig...
Today
Nurse Practitioner or Physician Assistant - Critical Care, Mercy Hospital St. Louis
$100K - $120K *
Engage with our Critical Care team to enhance patient outcomes through expert care, rounding in the ICU, performing procedures, and responding to rapid calls. Collaborate with physicians and support s...
Reposted 3 days ago
$85K - $125K *
Contribute to acquiring and managing data partnerships, collaborating with product teams to prioritize and improve dataset quality, while leveraging AI to enhance data processes and achieve business o...
Reposted 3 weeks ago
Client Growth & Success Manager
$100K - $115K *
Build strong client partnerships and drive growth by managing a portfolio of mid-sized employers. Collaborate cross-functionally to enhance engagement, retention, and revenue while delivering data-dri...
2 weeks ago
Pharmacy Eligibility/Claims Business Analyst
$54K - $145K *
Unlock potential by collaborating with cross-functional teams to deliver impactful analysis and requirements for Medicare and Medicaid enrollment solutions within an Agile framework, ensuring seamless...
Reposted today
$74K - $124K *
Lead audit remediation initiatives by coordinating with stakeholders, analyzing findings, and developing strategies to enhance internal controls and audit readiness, ensuring successful outcomes for f...
6 days ago
Clinical Dietitian, Acute Care, Jefferson City
$63K - $104K *
Join a team that's dedicated to enhancing patient care through expert nutrition assessments and interventions. Collaborate with healthcare professionals to provide individualized nutrition education a...
4 days ago
Clinical AI Technical Integration Specialist
$110K - $130K *
Unlock potential by driving technical integration and validation for Ambient AI Scribe initiatives. Collaborate with clinical teams to enhance workflows, troubleshoot issues, and ensure operational re...
2 weeks ago
Senior Associate, Market Intelligence
$80K - $95K *
Optimize market intelligence within global diagnostics by leading analytical work, synthesizing data, and translating complex insights into actionable recommendations. Collaborate with diverse stakeho...
3 weeks ago
Program Analyst (Earned Value Management)
$80K - $95K *
Transform project outcomes by analyzing performance data, forecasting costs, and ensuring compliance. Collaborate with contractors to identify risks and present actionable insights to leadership, driv...
6 days ago
$95K - $115K *
Unlock the potential of seamless data exchange by analyzing EDI requirements, developing maps, and supporting integrations. Collaborate with partners to ensure efficient transactions and enhance elect...
1 week ago
$100K - $104K *
Transform financial management for Foreign Military Sales by providing essential support and analysis. Collaborate with stakeholders to ensure compliance and accuracy in financial reporting and case m...
2 weeks ago
Senior Director, Business Management & Execution Lead
$170K - $200K *
Champion operational excellence by leading business unit strategies, enhancing performance management, and driving cross-functional collaboration to achieve enterprise goals and scalable solutions...
Yesterday
Configuration Analyst - Drug File/VA Oracle Health (Hybrid Kansas City MO Office)
$53K - $132K *
Optimize the configuration and implementation of Oracle Health Drug File systems for client projects. Collaborate with cross-functional teams to ensure successful execution and provide technical exper...
Reposted 2 days ago
$140K - $160K *
Accelerate progress at a dynamic tech firm by owning the full sales cycle for mid-market practices. Collaborate with leadership to shape strategy and drive impactful relationships, ensuring success in...
1 week ago
Senior Analyst-Global Operations and Automation
$88K - $105K *
Transform global operations by supporting Power Automate workflows, enhancing collaboration with regional teams, and driving continuous improvement in automation processes to optimize efficiency and e...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.