Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$135K - $173K *

Advance your career as a valued member of a multidisciplinary team, providing specialized research procedures and patient care across diverse medical settings, while leveraging your skills and experie...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $115K *

Unlock your potential in a pivotal integration role, ensuring customer success through seamless technical setups, collaboration across teams, and enhancement of integration performance for optimal sat...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$167K - $191K *

Lead the development and execution of HEOR/RWE strategies for neurology assets, ensuring robust evidence generation from early development through launch. Collaborate with cross-functional teams to su...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $160K *

Join a dynamic team of engineers to develop innovative software solutions, enhance user experiences, and drive impactful projects. Collaborate across functions while embracing modern technologies and...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $136K *

Join a team that's redefining biotech by bridging scientists and engineers. As a Business Analyst, you'll translate complex biological workflows into actionable insights, driving innovation in multi-o...

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $140K *

Lead the charge in implementing and maintaining ISO 27001:2022 compliance, driving cross-functional initiatives, and enhancing the Information Security Management System while collaborating with diver...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Consumer Technology

$72K - $111K *

Join a dynamic team to lead IT procurement efforts, overseeing the full purchasing cycle. Ensure compliance with Government requirements while facilitating timely acquisition of materials for critical...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the charge in designing innovative solutions across multiple higher education platforms. Collaborate with teams to implement best practices and ensure alignment with institutional goals, driving...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $150K *

Elevate your career by leading innovative research initiatives that shape industry strategies. Collaborate with top brands, utilizing your expertise in qualitative and quantitative methods to deliver...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$113K - $141K *

Transform the landscape of Corporate Finance by executing analyses, managing compliance, and supporting treasury and tax functions. Collaborate across teams to enhance processes and build a robust fou...

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$159K - $257K *

Transform security posture by leading enterprise vulnerability management, prioritizing risks, and driving remediation efforts across diverse technology environments. Collaborate with teams to enhance...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$212K - $318K *

Champion innovative actuarial solutions and enhance client relationships while leading engagements, ensuring exceptional service delivery in a dynamic health-focused environment...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $250K *

Drive innovation in data science by leading a talented team to transform life sciences data into actionable insights. Collaborate with leadership to implement AI strategies and ensure the delivery of...

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $250K *

Shape the future of data science in life sciences by leading a talented team to implement AI-driven solutions. Collaborate with global leaders to transform strategy into impactful analytics and foster...

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$81K - $210K *

Join a team that's dedicated to enhancing nursing knowledge and improving patient outcomes through innovative educational programs and clinical leadership. Collaborate with nursing leadership to ensur...

Today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$165K - $215K *

Shape the future of value-based payments by leading product strategy, overseeing team development, and driving market innovations within a collaborative, cross-functional environment...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$262K - $404K *

Optimize patient care and operational leadership as you manage Anesthesia APP teams, ensure regulatory compliance, and build strong client relationships while driving growth in practices and enhancing...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K *

Advance clinical documentation quality by conducting thorough reviews and facilitating physician interactions to enhance accuracy and compliance in medical records, ensuring optimal patient care and r...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive revenue growth and strategic account management across a diverse portfolio. You'll own the full sales cycle, collaborate with cross-functional teams, and build lasting relatio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$137K - $235K *

Unlock potential by leading data science initiatives that drive real-world evidence strategies in Immunology. Collaborate with cross-functional teams to translate complex data into actionable insights...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $130K *

Drive innovative clinical trial strategies across US and EU for neurodegenerative diagnostics. Collaborate with cross-functional teams to ensure regulatory compliance and achieve key milestones in pro...

6 days ago

  •   Less than 5 years exp.  •   Business Services

$147K - $220K *

Optimize specialty pharmacy analytics by transforming complex data into actionable insights. Collaborate with cross-functional teams to enhance channel performance, support patient access, and drive s...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$274K - $457K *

Accelerate innovative clinical development strategies while leading cross-functional teams. Foster collaboration to ensure timely regulatory submissions and optimal trial execution within the internal...

Reposted 6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$350K - $450K *

Lead transformative pricing and analytics initiatives across North America, leveraging actuarial expertise and advanced technology to drive growth, enhance client relationships, and deliver measurable...

2 days ago

  •   11 - 15 years exp.  •   Finance & Insurance

$100K - $120K *

Drive comprehensive health assessments by traveling to patients' homes, ensuring accurate documentation and patient education. Collaborate with healthcare teams to enhance care continuity while managi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.