Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$87K - $97K *

Shape the future of home health care by providing skilled nursing and case management to patients in their homes. Utilize your clinical expertise to enhance patient independence and coordinate care ef...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Lead the daily operations of a Family Birthplace, ensuring compliance and excellence in care. Supervise staff, participate in hiring, and uphold regulatory standards while fostering a positive environ...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$218K - $249K *

Transform AI research into impactful products by collaborating with cross-functional teams. Leverage advanced technologies to develop AI foundation models, driving innovation and enhancing customer ex...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$128K - $150K *

Help us drive growth in the Home Health and Pediatric Care sectors by generating new enterprise revenue. Own the full sales cycle, engage decision-makers, and develop strategic relationships to establ...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$128K - $140K *

Transform financial management processes by leveraging your expertise to support acquisition-related activities, ensuring effective budgeting, reporting, and compliance within DoD frameworks across mu...

4 days ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Innovate data solutions for enterprise analytics and operations. Collaborate with cross-functional teams to enhance data infrastructure while ensuring compliance and supporting BI needs on the Azure p...

Reposted 1 month ago

  •   Less than 5 years exp.  •   Business Services

$78K - $95K *

Engage in a collaborative care model to integrate behavioral health into primary care, providing essential support for mental health and substance use disorders through assessment, treatment planning...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $165K *

Champion safety in innovative nuclear fuel recycling by evaluating hazards, developing safety documents, and ensuring compliance with regulations. Collaborate in a dynamic team to enhance safety measu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$180K - $195K *

Drive impactful data science initiatives by building and operating ML systems. Manage end-to-end processes from modeling to evaluation, while mentoring a lean team and collaborating across departments...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$158K - $210K *

Accelerate progress at the intersection of AI and financial services, leading the development of innovative solutions that enhance operations in lending, payments, and asset management while collabora...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Drive data-driven decision-making by transforming complex data into actionable insights. Collaborate with cross-functional teams to enhance reporting and analytics using advanced SQL and AI tools, ens...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$80K - $95K *

Champion exceptional research outcomes by guiding clients through complex projects. Leverage your expertise in methodology and analysis to deliver actionable insights, while collaborating with cross-f...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$150K - $185K *

Shape the future of healthcare strategy by leading brand initiatives, mentoring talent, and driving impactful storytelling to elevate strategic excellence across teams and agency collaborations...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Healthcare

$110K - $130K *

Drive governance and controllership for LTC actuarial models, ensuring compliance and effective controls. Collaborate with cross-functional teams to enhance processes and documentation, supporting mod...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$60K - $129K *

Join a team that's dedicated to enhancing health outcomes by assessing, planning, and coordinating care for members. Collaborate with multidisciplinary teams to navigate healthcare needs and implement...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $287K *

Lead the charge in clinical science strategy, partnering with Medical Directors to design impactful studies, ensuring patient safety and data integrity while mentoring junior colleagues and driving pr...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$61K - $122K *

Transform clinical genetic curation by collaborating cross-functionally to enhance genomic testing, ensuring compliance with guidelines while supporting innovative health initiatives and improving pat...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $105K *

Join a team that's dedicated to enhancing customer success through strategic account management, driving RQI Portfolio adoption, and building lasting relationships to support our lifesaving mission in...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $105K *

Inspire customer success by managing accounts, driving RQI adoption, and building lasting relationships. Utilize a consultative approach to achieve financial goals while ensuring customer health and m...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Champion clinical education and training by delivering expert knowledge and support to enhance user competencies and optimize patient care within a defined territory. Build strong relationships with s...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$160K - $180K *

Unlock insights in a hands-on analytics role, guiding commercial strategy through data interpretation, leading patient services analytics, and enhancing market access with actionable recommendations a...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock the potential of data as a senior data scientist, transforming U.S. Army enterprise data into impactful analytical products and workflows, while collaborating with cross-functional teams to dri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$180K - $220K *

Empower innovation in clinical trials by developing strategies, overseeing operations, and cultivating partnerships. Drive excellence in research, enhance compliance, and manage a high-performing team...

RemoteRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$79K - $204K *

Unlock potential by leveraging clinical expertise to enhance care delivery. Collaborate with multidisciplinary teams to implement IT solutions, streamline processes, and improve patient outcomes in a...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$69K - $100K *

Elevate your career by joining a dynamic sales team aimed at enhancing customer engagement through diagnostic solutions. Travel extensively within your territory to drive sales, build relationships, a...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.