Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$73K - $125K *

Transform clinical review processes by conducting thorough prepayment and post-payment assessments of inpatient admissions. Leverage your expertise to ensure compliance, support appeals, and enhance q...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$108K - $130K *

Transform healthcare privacy by leading compliance initiatives and guiding hospital leadership. Collaborate across teams to ensure adherence to regulations, manage incidents, and foster a culture of p...

Yesterday

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$120K - $135K *

Empower clinical research excellence by managing projects that ensure compliance with regulatory requirements and drive successful study delivery from initiation to closeout. Collaborate with interdis...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$77K - $99K *

Unlock potential by leading investigations into fraud, waste, and abuse in Medicaid. Ensure compliance through quality audits and manage regulatory deliverables, collaborating with stakeholders to uph...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$75K - $90K *

Optimize the Yardi platform by administering, configuring, and enhancing its functionalities. Collaborate with cross-functional teams to ensure efficient business processes and support system improvem...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$73K - $132K *

Drive organizational change by analyzing processes, engaging stakeholders, and implementing effective strategies. Collaborate with teams to enhance operational efficiency and ensure successful adoptio...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Technical Services

$160K - $190K *

Unlock potential by leading enterprise-wide data and AI governance initiatives. Drive strategic frameworks, ensure compliance, and foster a culture of responsible data use while enhancing analytics ca...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Energy & Utilities

$135K - $145K *

Drive procurement excellence by developing and executing strategies for indirect spend commodities, enhancing supplier relationships, and achieving cost savings while collaborating with stakeholders t...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$160K *

Champion data-driven insights to guide strategic decisions, mentor junior staff, and lead projects. Analyze audience and market data to optimize media and marketing strategies, ensuring alignment with...

Reposted yesterday

  •   Less than 5 years exp.  •   Media

$140K - $170K *

Shape the success of enterprise health systems by leading full implementations. Collaborate cross-functionally to manage project lifecycles, mitigate risks, and ensure smooth transitions to customer s...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$290K *

Elevate your career by providing expert anesthesia care in diverse clinical settings. Collaborate with multidisciplinary teams to ensure patient safety and quality outcomes while engaging in education...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading strategic growth initiatives in the Public Sector. As a trusted advisor, you'll enhance client relationships and drive adoption of innovative health solutions, ensuring mea...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Join a team that's dedicated to optimizing our Knowledge Management platform by managing access, analyzing workflows, and translating business needs into actionable requirements. Collaborate with cros...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$90K - $110K *

Join a dynamic team to design and implement a robust testing platform, ensuring high software quality through effective test development and collaboration with DevOps and development teams in a fast-p...

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$156K - $235K *

Accelerate your career by leading Theranostics initiatives within a national healthcare advisory team. Collaborate with executives to enhance patient outcomes and operational performance through strat...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$210K - $250K *

Elevate healthcare delivery by providing remote GI services to Veterans. Collaborate with facility leaders to establish clinics, manage patient panels, and ensure timely access to care while adhering...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$137K - $235K *

Lead a dynamic team to advance data science and AI capabilities in Finance. Drive impactful analytics solutions that enhance decision-making and efficiency across key financial processes, while foster...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$137K - $235K *

Inspire data-driven decision-making by leading a team in developing advanced analytics and AI solutions that enhance financial processes, improve forecasting, and drive efficiency across multiple busi...

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by supporting clinical studies through scientific expertise, operational delivery, and compliance. Collaborate with cross-functional teams and stakeholders to ensure successful tri...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$91K - $179K *

Lead the charge in designing and delivering AI solutions that enhance Human Capital products. Collaborate with cross-functional teams to build scalable, secure, and efficient data pipelines and LLM ap...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$112K - $125K *

Join our team to advance therapeutic discovery by designing and executing in vitro and in vivo studies, optimizing CAR constructs, and evaluating gene delivery and immune responses for next-generation...

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$164K - $282K *

Lead the design and deployment of AI solutions for Neuroscience R&D, translating research needs into scalable tools. Drive multidisciplinary collaboration, establish evaluation practices, and ensure s...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$122K *

Champion clinical excellence by leading large teams, ensuring strategic alignment, and driving patient recruitment while mitigating risks in clinical operations for successful study execution...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$125K - $140K *

Lead transformative healthcare initiatives by fostering client relationships, driving impactful research, and developing high-performance teams to achieve strategic goals and business growth...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Unlock potential by driving strategic initiatives and enhancing operational excellence within the Global People Analytics & Experience function. Collaborate across teams to translate priorities into a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.