Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$103K - $128K *

Shape the future of healthcare by driving risk adjustment solutions that enhance interoperability, improve documentation accuracy, and ensure compliance across Medicare, Medicaid, and ACA programs thr...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$103K - $128K *

Join us to lead product strategy and development, driving innovation and performance in healthcare solutions. Collaborate cross-functionally to align business needs with customer expectations and ensu...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $118K *

Empower individuals by delivering skilled occupational therapy interventions while collaborating with healthcare teams. You will promote patient wellness, ensure documentation compliance, and provide...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $120K *

Lead the charge in enhancing commercial insurance products by collaborating with cross-functional teams. Drive requirements documentation, user acceptance testing, and system training to ensure compli...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$394K - $481K *

Lead the charge in clinical development strategy for groundbreaking gene-editing therapies. Collaborate with cross-functional teams to drive innovative solutions and ensure compliance, while providing...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive clinical quality improvements by translating needs into training and processes. Own record audits, partner with Product and Engineering for automation, and support clinical projects to enhance p...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $125K *

Drive the deployment of healthcare technology across multiple VA facilities, coordinating projects and ensuring readiness. Collaborate with diverse teams to manage timelines, resolve issues, and deliv...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $173K *

Join a team that's redefining AI-driven quality and performance operations. You'll build systems that enhance frontline team effectiveness and AI agent performance, ensuring impactful coaching and fee...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$50K - $200K *

Drive results as you manage a portfolio, utilize sales tools, and collaborate to achieve quotas. Become a subject matter expert while engaging with clients, ensuring high retention and success in new...

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$180K - $220K *

Accelerate progress by leading global regulatory strategies for diverse clients, ensuring compliance and fostering relationships with key regulatory bodies to enhance project success across therapeuti...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$119K - $152K *

Join a team that's dedicated to providing comprehensive obesity care to adolescents and adults. Engage in a collaborative environment, empowering patients through evidence-based treatment while enjoyi...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $113K *

Transform data integrity by assisting in the analysis and cleansing of Enterprise Business Systems. Collaborate with teams to resolve anomalies and ensure compliance with DoD standards while supportin...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$180K - $220K *

Empower global regulatory strategies and drive business growth while leading multidisciplinary collaborations in a fast-paced environment. Leverage your expertise to guide clients through complex regu...

Boston, MARemote

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$140K - $170K *

Elevate your career by managing a dynamic Palliative Care Program, providing clinical expertise, and leading a dedicated team. Drive process improvements and ensure high-quality patient care while fos...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $115K *

Join a team that's driving innovative investment solutions in the GIC business. Collaborate with diverse stakeholders to manage portfolios, execute trades, and analyze market dynamics while enhancing...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $120K *

Empower patient care as a registered nurse, providing essential support and assessments for respite patients. Collaborate with a dedicated team to ensure high-quality nursing care and timely intervent...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$86K - $109K *

Transform organizational initiatives by leading complex projects, ensuring strategic alignment, driving stakeholder engagement, and implementing best practices to achieve enterprise-level objectives a...

4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$68K - $113K *

Elevate your career by leading strategic sales compensation initiatives, leveraging advanced analytics to drive performance and enhance decision-making. Collaborate with senior leaders to design and i...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $104K *

Unlock potential by engaging affluent clients, fostering relationships, and collaborating with financial experts to deliver tailored wealth management solutions that exceed expectations and drive grow...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Transform client relationships by engaging affluent individuals, driving growth in deposits and investments, and collaborating with financial advisors to deliver personalized strategies that meet thei...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Lead the charge in delivering exceptional client experiences for affluent individuals. Collaborate with Wealth Advisors to develop personalized financial strategies, ensuring long-term relationships a...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Transform client relationships by engaging affluent clients, driving growth through personalized financial strategies, and collaborating with a dedicated team to deliver exceptional service and achiev...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Join a team that's dedicated to delivering exceptional service to affluent clients. Engage in strategic financial planning, foster long-term relationships, and collaborate with Wealth Advisors to achi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Drive your career forward by engaging affluent clients, fostering relationships, and collaborating with financial experts to deliver personalized strategies that meet their financial goals and enhance...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $104K *

Unlock potential by engaging affluent clients, driving growth in deposits and investments, and collaborating with Wealth Advisors to deliver tailored financial strategies and exceptional service, ensu...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.