Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$87K - $107K *

Deliver optimal health outcomes by facilitating care for complex healthcare needs, using clinical skills and managed care principles. Collaborate with a dedicated team to authorize necessary services...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $155K *

Drive regulatory strategies and compliance for high-risk medical devices, ensuring successful market approval and navigating complex global regulations while collaborating with cross-functional teams...

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$177K - $278K *

Unlock strategic insights in oncology by leading competitive intelligence efforts. Drive team performance, anticipate market shifts, and deliver actionable recommendations to inform brand and portfoli...

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Shape the future of patient care by leading nursing operations, mentoring staff, and ensuring compliance with quality standards. Drive initiatives for restorative and infection control programs while...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion data-driven decision-making by owning analytical functions across key business areas. Collaborate with teams to define problems, derive insights, and drive impactful outcomes that enhance gro...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$140K - $175K *

Empower scientific innovation by collaborating within product pods to develop and evaluate real-world evidence agents. Drive impactful research and ensure scientific rigor while partnering with indust...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $98K *

Transform clinical research finance by overseeing accounts receivable and payable, ensuring compliance with contracts, and mentoring junior staff. Drive financial accuracy and efficiency across multip...

5 days ago

  •   Less than 5 years exp.  •   Healthcare

$206K - $297K *

Shape the future of real-world evidence strategy by leading innovative studies, collaborating with global teams, and driving impactful decisions that enhance clinical and regulatory strategies for ass...

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$172K - $202K *

Discover innovative insights into AI's economic impact. Leverage analytics and market dynamics to shape vital research while influencing industry leaders with cutting-edge strategies and actionable ad...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Business Services

$90K - $110K *

Take ownership of designing, building, and maintaining critical IT system integrations, ensuring data flow and operational efficiency while troubleshooting complex issues and optimizing performance in...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$162K - $271K *

Elevate your career by driving field and account strategy through insights and analytics. Collaborate with sales leadership to enhance executional excellence and deliver high-quality insights that inf...

Reposted 2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Lead and develop a high-performing rehab team in a supportive long-term care environment. Oversee clinical operations, ensure quality therapy services, and drive program growth while fostering a posit...

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $161K *

Empower our Quality Engineering operations by managing portfolio governance, financial planning, and resource allocation. Collaborate across teams to enhance transparency and execution, driving strate...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $161K *

Shape the future of Quality Engineering by leading portfolio management, financial governance, and strategic execution. Collaborate across teams to enhance operational effectiveness and drive transfor...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $156K *

Elevate your dental career by providing essential services in long-term care facilities. Enjoy flexible scheduling, clinical autonomy, and a supportive environment while earning competitive pay and be...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$195K - $220K *

Unlock potential by leading a dynamic team in strategic operations, finance, and personnel management. Drive innovation and efficiency in a mission-driven environment, ensuring alignment with institut...

4 days ago

  •   11 - 15 years exp.  •   Healthcare

$159K - $197K *

Drive compliance excellence in clinical development by providing technical leadership and oversight in GCP, GVP, GLP, and GPP. Collaborate with cross-functional teams to ensure quality and readiness f...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $149K *

Unlock potential by leading healthcare data analytics to enhance hospital quality performance and rankings. Collaborate with teams to design dashboards, mentor analysts, and present insights to execut...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$74K - $115K *

Join a dynamic team to develop and support SQL-based ETL processes, ensuring data quality and integration performance across business applications. Collaborate with technical teams to enhance data exc...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$195K - $341K *

Champion quality improvement initiatives by developing and implementing clinical care standards. Lead operational strategies, ensure compliance with regulations, and provide training and support to en...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by cultivating strategic relationships with benefits consultants and brokers. Drive revenue growth through effective partnerships, collaboration with cross-functional teams, and exper...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $114K *

Optimize financial systems as a Business Analyst, ensuring robust functionality of SAP S/4HANA. Collaborate with IT and Finance to support system integrity and enhance operational efficiency through a...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a dynamic team to design and develop innovative automation solutions. Leverage your expertise in application development and automation tools to enhance efficiency and drive strategic goals withi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Drive security excellence by managing identity access, external testing, and compliance processes. Collaborate with teams to enhance AWS security and develop scalable policies, ensuring robust protect...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.