Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$123K - $183K *

Drive patient care excellence by coordinating complex cases, ensuring quality outcomes, and optimizing resource utilization. Collaborate with interdisciplinary teams to facilitate timely discharges an...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$79K - $157K *

Advance clinical data insights by reviewing and analyzing trial results, collaborating with cross-functional teams to ensure data integrity, and presenting findings to stakeholders, enhancing study ou...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$280K - $360K *

Transform healthcare delivery by leading comprehensive medical services, ensuring high-quality, patient-centered care while managing a dedicated team in a dynamic environment. Drive initiatives that e...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$95K - $115K *

Grow and manage a dedicated hospice nursing team, ensuring high-quality patient care and compliance with regulations while leading administrative functions and staff development efforts...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $187K *

Elevate your career by managing client engagements and delivering strategic solutions in government healthcare consulting. Leverage your actuarial expertise to drive impactful analyses and foster grow...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$93K - $187K *

Join a team that's shaping the future of health actuarial services. Leverage your expertise in Medicaid leadership and client management to drive impactful strategies and solutions while embracing inn...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$184K - $396K *

Shape the future of healthcare technology by leading clinical informatics initiatives, enhancing patient outcomes, and driving enterprise-wide Epic optimization within a dynamic team of experts dedica...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $178K *

Advance patient care by leading a dedicated nursing team in a specialized oncology unit, ensuring high-quality clinical outcomes and fostering a positive work environment for staff and patients alike...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $195K *

Innovate member experience strategies by translating enterprise goals into actionable plans. Drive performance improvements in CAHPS and HOS programs through provider engagement and data analysis, ens...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $119K *

Engage in impactful clinical documentation audits to enhance quality, compliance, and education. Drive improvements in CDI processes and patient care while collaborating with healthcare teams to ensur...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $188K *

Transform research accounting systems by designing, implementing, and optimizing Workday and related tools. Collaborate with cross-functional teams to enhance financial management and reporting capabi...

Brookline, MARemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$170K - $188K *

Transform research financial management by optimizing Workday and related systems. Collaborate with cross-functional teams to enhance accounting capabilities, ensuring compliance and efficiency in rep...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $155K *

Lead the charge in designing and launching innovative enterprise solutions for healthcare clients, enhancing consumer applications while ensuring compliance and security standards are met. Collaborate...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$98K - $133K *

Transform nursing policy governance and clinical standards across a large health system. Collaborate with diverse teams to ensure compliance, enhance communication, and drive evidence-based practices...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $133K *

Join a team that's dedicated to enhancing nursing policy governance and clinical standards. Leverage your expertise to manage complex projects, improve processes, and ensure compliance across a large...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $133K *

Join a team that's dedicated to enhancing nursing policy governance and clinical standards. This role involves coordinating policy development, managing interdisciplinary collaboration, and ensuring c...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$98K - $133K *

Lead the development and governance of nursing policies and clinical resources, ensuring compliance and alignment with best practices. Collaborate with interdisciplinary teams to enhance clinical stan...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $90K *

Pioneer innovative solutions by supporting clients and teams in managing employee benefits. Utilize your expertise to enhance service delivery, streamline processes, and drive successful outcomes in b...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Drive business analysis by gathering requirements, documenting processes, and validating Salesforce solutions to enhance customer satisfaction and operational efficiency through effective stakeholder...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Business Services

$93K - $132K *

Lead the charge in developing and maintaining dental coverage policies, ensuring clinical integrity and compliance. Collaborate across teams to enhance program infrastructure and support regulatory au...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$136K - $187K *

Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$146K - $211K *

Pioneer growth in rare disease management by driving sales, optimizing care pathways, and enhancing patient outcomes through strategic partnerships and innovative solutions in a dynamic healthcare env...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Champion data-driven space planning initiatives by analyzing complex inventories, collaborating with multidisciplinary teams, and delivering insights to enhance campus environments and optimize resour...

2 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$68K - $105K *

Unlock potential by configuring and supporting Epic Orders applications. Engage in business analysis, system design, and user support to enhance workflows and resolve issues, while managing projects a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $115K *

Unlock the potential of healthcare data by developing reproducible analytic workflows. Collaborate with a multidisciplinary team to analyze large datasets, translating research questions into actionab...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.