Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$73K - $125K *

Unlock potential by conducting in-depth policy analysis and quantitative research to support environmental and public health initiatives. Collaborate with multidisciplinary teams to inform regulatory...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$73K - $125K *

Empower your career by providing critical analysis and consulting for environmental and public health programs. Collaborate with multidisciplinary teams to develop evidence-based solutions and support...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$95K - $115K *

Drive provider network excellence by managing data integrity, overseeing contract configurations, and leading cross-functional teams to enhance operational efficiency and compliance in a dynamic TPA e...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Champion innovative solutions as a Business Solutions Analyst, collaborating with healthcare organizations to drive strategic initiatives and operational excellence across diverse projects and deliver...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Shape the future of clinical research data integrity by leading a dedicated team. Drive operational excellence, ensure compliance, and foster cross-functional partnerships to enhance data quality and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Help us shape the future of our operations by designing AI-enabled processes. Collaborate with cross-functional teams to map current workflows, identify automation opportunities, and drive transformat...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Drive AI transformation by mapping current processes and designing future-state models across G&A functions. Collaborate with stakeholders to identify automation opportunities and enhance operational...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Shape the future of AI in healthcare by leading enterprise-wide adoption, governance, and risk management. Drive innovation and compliance while ensuring AI initiatives deliver measurable business val...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$104K - $143K *

Advance clinical risk management by identifying, assessing, and mitigating risks in patient care and operations. Collaborate with leaders to enhance safety and compliance, ensuring effective strategie...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Unlock potential by joining a global team focused on clinical research compliance. You will negotiate and interpret informed consent for biospecimens, shaping the future of precision medicine and ensu...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Advance clinical documentation accuracy by collaborating with healthcare teams to ensure comprehensive patient records, reflecting severity of illness and risk of mortality, while maintaining complian...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$66K - $105K *

Empower the insurance recovery team by managing complex data analysis, document organization, and case management tasks. Play a key role in supporting litigation efforts through research, reporting, a...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$64K - $120K *

Unlock potential by joining a dynamic team that delivers tailored employee benefits solutions, fosters client relationships, and navigates compliance challenges to drive success in the health and welf...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$138K - $201K *

Architect cloud-based data solutions and drive enterprise data strategy. Leverage advanced analytics and modern data architectures to enhance operational efficiency and compliance in healthcare data m...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $180K *

Lead the charge in delivering innovative Federal healthcare projects, driving growth and client engagement while managing multidisciplinary teams through all project phases to ensure excellence and co...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$128K - $147K *

Manage risk management activities and patient safety initiatives, providing expert consultation and analysis to enhance safety culture and mitigate risks across the organization. Collaborate with inte...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform the landscape of performance analysis by utilizing your investment expertise and technical skills to deliver accurate, timely reports and drive operational improvements across teams and proj...

1 month ago

  •   Less than 5 years exp.  •   Business Services

$195K - $217K *

Drive client success by leading strategic initiatives and fostering strong relationships in healthcare technology. Leverage deep domain expertise to enhance outcomes and ensure effective use of soluti...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $95K *

Manage and coordinate home health services, ensuring quality care delivery and compliance with standards. Facilitate communication among patients, caregivers, and healthcare providers to maintain cont...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$178K - $257K *

Strategize and lead analytical initiatives for evolving customer and payer contracting models, ensuring cross-functional alignment and driving major transformation efforts within Contract Analytics to...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $121K *

Join a team that's redefining financial analytics by developing cutting-edge predictive models. Collaborate globally, analyze large datasets, and drive impactful solutions in the financial services in...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$70K - $120K *

Lead transformative Medicaid initiatives by guiding project oversight, ensuring timely execution, and enhancing stakeholder engagement. Collaborate with teams to streamline operations and achieve stra...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Business Services

$100K - $165K *

Optimize data systems by designing and maintaining scalable solutions that enhance decision-making. Collaborate across teams, mentor junior engineers, and streamline data processes to ensure high-qual...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Unlock potential by collaborating across teams to drive data integrity and safety in oncology clinical studies while developing comprehensive medical review plans and managing project deliverables...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.