Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$95K - $115K *

Lead the charge in enhancing clinical data quality and interoperability. Collaborate with clinical evaluators and product teams to drive improvements in healthcare data management and support quality...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Information Technology

$100K - $125K *

Transform your career by enhancing our global IT infrastructure and security. Engage in a dynamic role that involves troubleshooting, automating tasks, and supporting a hybrid environment while collab...

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$57K - $120K *

Drive operational excellence by supporting a multi-channel sales force, enhancing sales-enablement technology, and leveraging data for impactful decision-making to achieve company growth goals...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $214K *

Transform AI solutions by architecting robust, scalable systems for agent integration and performance within Cloud environments, driving quality and innovation in collaboration with engineering teams...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $280K *

Transform healthcare operations by leading finance, supply chain, and HCM consulting projects. As a Senior Manager, you'll drive efficiency and technology integration, guiding teams through complex tr...

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$124K - $280K *

Transform healthcare operations by leading finance, supply chain, and HCM consulting projects. Drive efficiency and technology integration while advising clients and guiding teams through complex tran...

6 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$109K - $144K *

Reimagine healthcare technology as an Application Analyst supporting Epic Professional Billing. Leverage your expertise in revenue cycle operations to optimize billing accuracy and enhance workflow ef...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $95K *

Advance patient care by providing evidence-based ABA services as a BCaBA, collaborating within a multidisciplinary team to support children's developmental needs while ensuring flexible scheduling and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$88K - $105K *

Join a team that's dedicated to enhancing client financial integrity by executing audits, preparing financial statements, and ensuring compliance with GAAP and SEC regulations while supervising junior...

Yesterday

  •   Less than 5 years exp.  •   Legal & Accounting

$178K - $257K *

Join a dynamic team as a lead biostatistician, guiding vital vaccine projects while ensuring scientific integrity and collaboration across global teams. Drive innovation and operational efficiency in...

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $127K *

Join a team that's dedicated to conducting in-depth investment research and analysis. You'll evaluate external managers and strategies, synthesize insights, and enhance our research capabilities to su...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$83K - $101K *

Lead the charge in supporting early drug discovery by translating scientific data needs into actionable insights. Collaborate across teams to enhance data product capabilities and improve research wor...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$136K - $239K *

Unlock your potential by leading statistical programming efforts in clinical trials. Collaborate with cross-functional teams to analyze and report clinical data, ensuring compliance with industry stan...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $95K *

Join a dedicated team providing skilled care to patients, teaching families, and collaborating with healthcare professionals to ensure effective service delivery in accordance with established care pl...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Engage in delivering skilled care to patients, collaborating with families and healthcare teams to ensure adherence to care plans and physician orders, while fostering a supportive environment for pat...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Empower patients by administering skilled care and educating families. Collaborate with healthcare teams to deliver services per physician orders and established care plans, ensuring high-quality pati...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$89K - $95K *

Advance your career by providing skilled care to patients, teaching families, and collaborating with healthcare teams to implement effective care plans. Make a meaningful impact in the lives of those...

3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $105K *

Collaborate with clients to analyze regulatory compliance and operational processes in Medicare Advantage, Medicaid managed care, and ACA programs. Conduct research, develop reports, and support proje...

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$140K - $150K *

Champion strategic IT staffing initiatives and lead a team of recruiters to optimize non-clinical recruiting processes, improve performance metrics, and enhance client satisfaction across various prof...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$70K - $118K *

Reimagine client engagement by managing Charles River IMS systems, ensuring seamless operations and expert support. Collaborate with teams to deliver top-tier service, enhance performance, and drive c...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$142K - $195K *

Unlock potential by leading transformative AI initiatives that enhance software delivery across IT disciplines. Drive organizational change while ensuring effective product engineering in a collaborat...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$76K - $131K *

Join a team that's redefining healthcare compliance by leading detailed coding audits, mentoring auditors, and driving innovative solutions to enhance compliance and operational excellence in a dynami...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$96K - $132K *

Join a team that's redefining enterprise operations through innovative AI solutions. Leverage your engineering expertise to design, deploy, and enhance AI agents that drive measurable business outcome...

5 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$93K - $97K *

Contribute to program success by supporting planning, execution, and management of projects. Analyze data, prepare reports, and optimize resources to ensure objectives are met within scope, time, and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.