Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$80K - $95K *

Elevate your career by supporting healthcare claims processing and system enhancements. Collaborate with stakeholders to translate business needs into actionable requirements, ensuring compliance and...

4 days ago

  •   Less than 5 years exp.  •   Staffing

$110K - $130K *

Join a team that's leading Medicaid programs and initiatives, driving operational excellence and policy implementation while managing multidisciplinary teams and enhancing organizational performance a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$85K - $95K *

Unlock potential by leading business analysis to transform processes into actionable requirements for a major financial management system. Collaborate with stakeholders to enhance workflows and ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $140K *

Join us in driving strategic insights through advanced analytics. You'll lead a team, develop client relationships, and enhance marketing strategies by translating data into actionable narratives that...

Today

  •   5 - 7 years exp.  •   Media

$106K - $147K *

Champion the development of ML pipelines, ensuring scalable, reliable decision-making systems that optimize member outcomes while collaborating with cross-functional teams to enhance platform performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$103K - $124K *

Join a team that's dedicated to advancing cancer diagnostics through innovative statistical analysis and collaboration. Contribute to study designs, regulatory submissions, and impactful research in a...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$93K *

Champion comprehensive health care services for individuals, ensuring optimal health and well-being. Oversee health assessments, manage documentation, and ensure the highest care standards in a suppor...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$163K - $218K *

Lead the strategy and delivery of enterprise applications, optimizing technology platforms to enhance clinical care and business operations. Collaborate with cross-functional teams to drive improvemen...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $95K *

Join a team that's driving innovation in clinical development. Leverage your strategic thinking and relationship-building skills to enhance client engagement and increase market presence in the biotec...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower growth by developing strategic relationships with biotech and pharma clients. Drive market awareness and increase RFPs through collaboration with the business development team, leveraging your...

RemoteRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$83K - $119K *

Shape the future of compensation practices by analyzing data, conducting market benchmarking, and maintaining job architecture to support a growing organization. Collaborate with HR and business leade...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $160K *

Analyze complex data and drive solutions as a Business Analyst in the public sector. Leverage your expertise in pension systems to identify issues and enhance processes, ensuring effective communicati...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$68K - $105K *

Champion the implementation and support of Epic Beaker applications, ensuring effective system design, user experience, and problem resolution while managing projects and enhancing end-user engagement...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$200K - $250K *

Shape the future of clinical research by leading complex trials and cross-functional teams. Drive high-quality data generation and ensure compliance while advancing innovative therapeutic strategies i...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$69K - $110K *

Transform technology risk evaluation through proactive audits, ensuring SOX compliance and robust control frameworks while collaborating with management on risk-based strategies and enhancements to bu...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$82K - $172K *

Lead the charge in managing program financials, ensuring compliance and accuracy in cost, funding, and forecasting while collaborating with project managers and support teams to drive project success...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $209K *

Join a team that's redefining data architecture and analytics. Leverage your expertise to drive cloud adoption, modernize data platforms, and influence strategic initiatives that empower data-driven d...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$117K - $161K *

Elevate your career by designing and optimizing scalable data solutions. Collaborate with cross-functional teams to transform complex data into actionable insights, ensuring high standards of quality...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$86K - $105K *

Analyze financial data and drive forecasting processes to support business leaders. Collaborate with cross-functional teams to enhance reporting accuracy and efficiency. Deliver insights through finan...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$241K *

Shape the future of healthcare consulting by leading client engagements, managing teams, and driving strategic growth initiatives in a dynamic practice area. Bring your expertise to influence and deve...

1 week ago

  •   5 - 7 years exp.  •   Business Services

$78K - $156K *

Join a team that's dedicated to enhancing business systems through design, configuration, and support. As a Senior Application Analyst, you'll lead improvements, mentor junior analysts, and ensure sea...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$78K - $156K *

Manage system design, enhancements, and support as a Senior Application Analyst. Collaborate with stakeholders, mentor junior team members, and improve workflows while ensuring application performance...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$179K - $298K *

Champion a dynamic team dedicated to enhancing state health and human services through strategic client engagement, quality delivery, and innovative business development while leading a diverse consul...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Business Services

$122K - $183K *

Transform risk adjustment data management by leading a team to ensure accurate, compliant submissions and reporting for Medicare Advantage. Collaborate across departments to optimize data integrity an...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$116K - $182K *

Engineer innovative solutions to complex WMD detection challenges while collaborating across multidisciplinary teams. Your contributions will enhance national security through the development of advan...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.