Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$115K - $163K *

Drive impactful performance insights by defining and managing the measurement framework for ancillary product portfolios, ensuring strategic alignment and regulatory compliance while advising leadersh...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $138K *

Elevate patient safety by leading risk management initiatives, ensuring compliance, and fostering a culture of safety across all clinical settings. Collaborate with diverse teams to identify, analyze...

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$59K - $109K *

Champion the optimization of security technology programs, collaborating with cross-functional teams to enhance global security operations. Manage projects from initiation to implementation, ensuring...

3 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$101K - $156K *

Elevate your career by configuring and enhancing Workday HCM solutions, driving user-centered processes and collaborating with stakeholders to deliver scalable, compliant solutions that support organi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Unlock potential by managing security data integrity and quality within Investment Operations. Collaborate with cross-functional teams to enhance operational strategies, streamline workflows, and supp...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$89K - $141K *

Champion data-driven insights by leading quality analytics initiatives, ensuring compliance and operational excellence in R&D. Collaborate with stakeholders to design impactful dashboards and enhance...

Reposted 5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to transforming healthcare data into actionable insights. This role involves analyzing complex datasets, collaborating with stakeholders, and delivering data-driven recomm...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$65K - $163K *

Join a team that's dedicated to impactful market access strategies by leveraging big data analytics. Develop expertise in quantitative methodologies, contribute to client engagements, and advance your...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead the charge in delivering high-quality care for patients with kidney-related conditions, collaborating with physicians and care teams to manage treatment plans, educate patients, and ensure smooth...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $140K *

Transform data into actionable insights by collaborating with leadership to analyze, visualize, and communicate findings. Leverage expertise in business intelligence tools to enhance decision-making f...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Drive transformation by collaborating with stakeholders to analyze and enhance business processes, ensuring effective technology adoption and operational improvements within a dynamic environment...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $145K *

Transform the future of AI initiatives by leading program management across teams, ensuring clear communication and governance. Drive strategic technology projects that enhance organizational capabili...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$90K - $120K *

Optimize operational excellence in healthcare IT by managing production support, driving issue resolution, and ensuring timely reporting for customer-facing technology delivery...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Analyze and optimize workforce management strategies across multiple business lines, translating complex forecasts into actionable capacity plans and financial models while collaborating with executiv...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion client success by overseeing relationships, ensuring operational excellence, and mentoring teams to exceed expectations. Utilize analytics to drive performance and resolve issues, fostering c...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$66K - $113K *

Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$92K - $167K *

Drive strategic initiatives in Medicare Advantage provider networks, analyzing data and collaborating with leadership to enhance performance and achieve goals. Lead complex projects from inception to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Elevate business processes by analyzing and transforming asset management systems with a focus on data strategy and AI. Collaborate with cross-functional teams to enhance delivery of digital capabilit...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$109K - $174K *

Drive significant advancements in drug safety by developing AI/ML models that enhance translational safety predictions. Collaborate with cross-functional teams to integrate complex data and improve de...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$78K - $113K *

Take ownership of financial management and operations for grant and contract activities, ensuring compliance and efficiency. Collaborate with internal teams and external partners to support effective...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$78K - $113K *

Transform financial operations and grant management for impactful projects. Collaborate with leadership and external partners to ensure effective budgeting, compliance, and reporting, while enhancing...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $151K *

Join a team that's shaping the future of insurance products by leading strategic initiatives, ensuring compliance, and driving market analysis. Collaborate with product managers to define vision and e...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$117K - $161K *

Drive impactful clinical intelligence initiatives by analyzing AI opportunities, conducting feasibility studies, and collaborating with cross-functional teams to enhance patient care and operational e...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $125K *

Join a dynamic team to oversee quality of care investigations and improvement initiatives, ensuring compliance with regulatory standards while enhancing patient outcomes and organizational efficiency...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Champion client success by leveraging advanced risk analysis tools to deliver tailored solutions. Collaborate across teams to optimize training and consulting efforts, ensuring clients maximize value...

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.