Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$180K - $220K *

Lead the charge in developing clinical content strategies and overseeing teams within the market access practice. Drive innovation, enhance client strategies, and ensure high standards in service deli...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $165K *

Elevate insider threat investigation capabilities by leveraging advanced analytics and risk assessment skills to support complex investigations and enhance organizational security posture against insi...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $117K *

Join a team that's dedicated to delivering financial insights and support across multiple manufacturing facilities. Leverage your analytical skills to drive performance improvements and assist in mont...

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$107K - $180K *

Lead the resolution of complex integration issues, collaborating with cross-functional teams to enhance reliability and support. Develop documentation and tools that empower partners and improve opera...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$250K - $350K *

Lead the development of a clinical supply consulting practice, combining expertise in forecasting, planning, and optimization to enhance decision-making for sponsors. Drive innovation and commercial g...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$158K - $170K *

Lead the development of predictive models integrating advanced ML techniques to drive strategic decision-making across credit risk, collections, and business operations while mentoring data scientists...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$223K - $313K *

Elevate healthcare outcomes by leading clinical determinations and authorizations. Utilize your medical expertise to ensure compliance with national guidelines while collaborating with diverse teams i...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Engineer scalable Azure data solutions, leading architecture and modernization initiatives. Collaborate with teams to define standards and ensure high-performance data integration, governance, and sec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Engage with us to drive innovative solutions in the healthcare supply chain. Collaborate closely with diverse teams, tackle complex challenges, and enhance patient care through strategic insights and...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Help us elevate value-based care by leading payer partnerships and health plan relationships. Drive strategic initiatives, foster cross-functional collaboration, and ensure successful Medicare Advanta...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$141K - $214K *

Engage with enterprise clients to drive Agentic AI adoption, leveraging your expertise in process intelligence to deliver bespoke B2B solutions that enhance operational efficiency and foster lasting r...

United StatesRemote

Reposted 5 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$95K - $120K *

Transform your career by joining a dynamic IT Services team as a ServiceNow System Administrator. Collaborate with stakeholders to design and enhance enterprise solutions, ensuring optimal performance...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$120K - $140K *

Transform the IT audit landscape by leading comprehensive assessments of cybersecurity, data privacy, and IT controls in a rapidly scaling telehealth environment. Collaborate with leadership to ensure...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Empower clinical trial design by architecting robust data infrastructures that streamline insights extraction from diverse clinical documents, enhancing decision-making through advanced data pipelines...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Transform relationships with key opinion leaders in rare neurological diseases, providing strategic insights and guidance to inform brand strategies and enhance engagement across medical and commercia...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$134K - $162K *

Contribute to the advancement of medical physics by leading dosimetry analysis for radiopharmaceuticals. Collaborate with cross-functional teams to drive research in drug development and improve imagi...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$116K - $215K *

Transform enterprise application management by leading design, customization, and implementation efforts. Collaborate with developers and stakeholders to ensure functional requirements are met while o...

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$120K - $160K *

Join a dynamic team to deliver high-level financial analysis and strategic insights across multiple business segments. Leverage your expertise to support senior leadership in capital markets and drive...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$115K - $130K *

Champion executive compensation strategies by managing program administration, collaborating with HR partners, and conducting market research to enhance compensation practices and support organization...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Shape the future of cybersecurity in higher education by delivering expert assessments, advisory services, and tailored remediation plans that empower institutions to enhance their security posture an...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Advance global clinical trials by leading cross-functional teams, ensuring compliance and operational excellence while managing timelines and budgets to deliver impactful results in Oncology research...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $115K *

Optimize warehouse operations by implementing WMS solutions. Collaborate with teams to enhance workflows, lead testing, and ensure successful deployments, driving efficiency and scalability in logisti...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Transportation

$80K - $110K *

Analyze diverse research projects to provide actionable insights for leadership. Collaborate with a dynamic team, utilizing AI tools and your curiosity to tackle complex questions and deliver clear, c...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$90K - $110K *

Lead the charge in developing and maintaining insurance policy forms and endorsements. Ensure compliance and quality assurance across multiple states while collaborating with cross-functional teams to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$180K - $220K *

Drive patient care excellence by delivering comprehensive medical assessments and treatments in a supportive outpatient setting, collaborating with a dedicated team to enhance health outcomes and ensu...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.