Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$100K - $120K *

Drive the configuration and enhancement of Workday Absence, Time Tracking, and Benefits systems. Collaborate with cross-functional teams to ensure seamless integration and support for global employee...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$200K - $250K *

Lead the charge in enhancing patient care while managing clinic operations, ensuring quality improvements and collaboration among healthcare teams to achieve optimal clinical outcomes and business suc...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Shape the future of workplace health by blending patient care with leadership. Drive clinical excellence and foster a collaborative environment while managing a dedicated team to enhance patient exper...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $190K *

Empower your career by partnering with the Science Leadership Team to drive strategic initiatives, enhance operational effectiveness, and translate scientific vision into impactful outcomes across div...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a dynamic team as a Dynatrace Administrator, optimizing environments and automating incident responses. Leverage your expertise to enhance performance monitoring and ensure seamless integration w...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Drive growth in digital therapeutics by engaging medical practices, guiding them from initial interest to consistent orders. Collaborate with sales and clinical teams to shape the onboarding process a...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $120K *

Transform cloud security operations by enhancing AWS and Azure environments. Lead initiatives to secure cloud-native capabilities, manage incident responses, and collaborate with engineering teams to...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Join a team that's dedicated to enhancing patient independence through collaborative rehabilitation. This role offers the chance to make a meaningful impact in a supportive environment, working closel...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$85K - $111K *

Unlock your potential by leading business and functional requirements for Medicaid financial management. Collaborate with diverse teams to enhance payment operations and ensure compliance while drivin...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$172K - $203K *

Elevate women's health outcomes by developing advanced machine learning models. Lead projects, mentor junior team members, and collaborate with cross-functional teams to drive innovation and commercia...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$170K - $195K *

Engage in strategic account acquisition for our Legal Technologies sector, focusing on sourcing, qualifying, and closing new enterprise accounts. Drive revenue growth through complex sales cycles whil...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Legal & Accounting

$130K - $150K *

Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Lead compliance excellence by conducting quality reviews, enhancing processes, and providing expert guidance to ensure timely, accurate client service and adherence to regulatory standards in a dynami...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$292K - $341K *

Shape the future of healthcare by leading a team of clinicians, driving clinical excellence, and enhancing patient outcomes while managing an active patient panel in a collaborative, supportive enviro...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Build innovative AI solutions that enhance software delivery by developing reusable components, collaborating with engineering teams, and ensuring reliable, secure AI workflows. Contribute to producti...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$184K - $218K *

Unlock potential by leading the strategy and management of IT applications for Market Access and Patient Services, enhancing patient journeys through innovative technology solutions and data-driven in...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $200K *

Unlock potential by providing strategic legal counsel on clinical and commercial operations, focusing on regulatory compliance, privacy, and data protection in a dynamic biopharmaceutical environment...

United StatesRemote

Reposted yesterday

  •   11 - 15 years exp.  •   Healthcare

$92K - $110K *

Drive the future of patient care by joining a dynamic team focused on delivering exceptional healthcare services. Collaborate with professionals in a fast-paced environment, ensuring quality treatment...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion client success by managing key relationships and driving strategic initiatives. Lead cross-functional teams to deliver high-quality work while ensuring financial performance and growth for as...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$57K - $113K *

Develop and enhance crisis management strategies to effectively respond to incidents. Lead training, assess risks, and ensure compliance with regulations while maintaining communication with stakehold...

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$120K - $130K *

Explore data-driven insights to enhance business intelligence and optimize performance. Collaborate with teams to analyze complex data, develop reporting structures, and present findings that influenc...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$80K - $95K *

Manage the implementation process for clients in Revenue Cycle Management, ensuring efficient setup and optimization of billing workflows. Serve as the primary expert, guiding healthcare organizations...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $160K *

Partner with us to drive effective cost management for global construction projects. Leverage your expertise to support project managers, optimize budgets, and mitigate risks, ensuring successful proj...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Drive impactful data analysis and risk management for global clinical trials, interpreting complex data to identify trends and risks. Lead cross-functional teams in enhancing study quality and patient...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Staffing

$98K - $160K *

Shape the future of clinical research by implementing innovative digital tools and technologies. Collaborate with cross-functional teams to ensure compliance and quality in study delivery while managi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.