Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

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$90K - $110K *

Deliver excellence in clinical research by managing monitoring activities, ensuring site compliance, and fostering strong relationships with investigators. Drive study integrity and patient safety whi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$71K - $97K *

Pioneer the integration of comprehensive assessments and discharge planning to ensure coordinated, quality care for admitted members, enhancing health outcomes and optimizing member wellness through c...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $97K *

Join a team that's dedicated to improving patient care through comprehensive assessments and coordinated discharge planning, ensuring a seamless transition for members from acute care to home and prom...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Drive statistical excellence in oncology clinical trials, ensuring accuracy and quality of deliverables while collaborating with diverse teams to support impactful research across various health secto...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$129K - $177K *

Join a team that's shaping innovative pricing strategies for Medicare Advantage products. Collaborate cross-functionally to analyze market data, establish financial metrics, and drive profitable growt...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Drive customer success by managing relationships and ensuring product adoption. Collaborate with teams to mitigate risks, enhance customer experience, and create growth opportunities while mentoring p...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$80K - $85K *

Unlock potential by driving new business and building relationships in mid-market food sectors. Focus on achieving sales targets, managing the sales process, and delivering tailored SaaS solutions tha...

United StatesRemote

Reposted 1 month ago

  •   Less than 5 years exp.  •   Food & Beverages

$68K - $105K *

Shape the future of Information Security by assisting in the design, development, and implementation of ISRM Infrastructure systems. Collaborate with teams to ensure compliance, analyze systems perfor...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $205K *

Lead the design and analysis of clinical validation studies, ensuring regulatory compliance and driving innovative research in molecular diagnostics. Collaborate with cross-functional teams to enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by driving ERP innovation and optimization. Collaborate with stakeholders to enhance Workday and corporate applications, ensuring seamless integration and maximum value delivery ac...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive operational excellence by managing departmental resources, improving processes, and ensuring high-quality patient care. Lead initiatives to enhance service delivery while maintaining fiscal resp...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $158K *

Drive strategies to enhance customer engagement and retention for pharmacy services. Collaborate with cross-functional teams to optimize member experiences, increase auto-refill adoption, and boost pr...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Healthcare

$103K - $140K *

Shape the future of supply chain analytics by leveraging AI and data science expertise to develop innovative solutions that enhance decision-making and user productivity across the organization...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Lead the design and implementation of scalable Identity Governance solutions, ensuring alignment with enterprise architecture. Drive technical excellence and operational reliability while mentoring en...

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a team that's dedicated to enhancing security operations through proactive monitoring, incident response, and client engagement. This role offers the chance to lead investigations and improve sec...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$87K - $157K *

Join a dynamic team to develop and enhance clinical systems, ensuring compliance with NIH standards. Collaborate with cross-functional teams to troubleshoot and implement solutions that improve health...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Shape the future of paid social marketing by driving acquisition and revenue growth across multiple consumer brands. Collaborate to build creative strategies, manage performance, and optimize campaign...

United StatesRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $129K *

Elevate client engagement through data-driven insights! As a Senior Analyst, you'll analyze performance metrics, enhance marketing strategies, and drive client retention, ensuring impactful decisions...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Legal & Accounting

$90K - $105K *

Pioneer innovative solutions as you apply advanced analytics to evaluate energy strategies, manage projects, and lead research efforts for utility and government clients, driving sustainability and ef...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$125K - $150K *

Architect innovative infrastructure solutions, driving technology implementation and ensuring alignment with enterprise architecture standards. Lead identity modernization initiatives and mentor teams...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$81K - $122K *

Join a dynamic team to support M&A activities through financial analysis, market research, and transaction coordination. Develop expertise in valuation concepts and contribute to deal documentation an...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Food & Beverages

$88K - $105K *

Unlock potential by transforming data into actionable insights that drive strategic decisions. As a key player, you'll enhance resource optimization across departments through impactful forecasts and...

4 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Pioneer comprehensive oncology programs by leading strategic growth initiatives, enhancing patient care, and collaborating with diverse teams to ensure exceptional outcomes and operational excellence...

1 week ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$190K - $240K *

Elevate healthcare impact by building and scaling enterprise accounts in women's health. Own the sales cycle, engage stakeholders, and drive screening initiatives while collaborating across teams to e...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $165K *

Partner with us to drive enterprise growth as you manage strategic relationships with healthcare systems. Your expertise will bridge teams and engage C-suite leaders, enhancing our portfolio value acr...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.