Explore $100K+ Jobs in Kentucky

Discover high-paying professional opportunities across Kentucky with Ladders. Browse vetted roles with salaries of $100,000 or more, from established employers and growing organizations. Whether you’re interested in positions in Louisville, Lexington, Bowling Green, or elsewhere in the state, find opportunities that fit your experience and career goals.

Professional Opportunities Across Kentucky

Kentucky’s economy spans healthcare, manufacturing, logistics, finance, technology, education, and other industries. Employers across the state seek experienced professionals for roles in leadership, operations, engineering, sales, healthcare administration, and more. The right opportunity may be available in a major metro area or in a smaller community.

Find a Role That Fits Your Experience

Use Ladders to explore opportunities suited to your skills, seniority, and compensation expectations. Review job descriptions, compare responsibilities, and identify roles where your professional background can make an impact. Listings on Ladders are vetted and pay at least $100,000.

Advance Your Career in Kentucky

Build your next career move by searching Kentucky jobs and narrowing results by location, industry, and role. Check listings regularly, tailor your resume to each opportunity, and highlight measurable accomplishments that demonstrate your value to prospective employers.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$109K - $144K *

Reimagine healthcare technology as an Application Analyst supporting Epic Professional Billing. Leverage your expertise in revenue cycle operations to optimize billing accuracy and enhance workflow ef...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$136K - $239K *

Unlock your potential by leading statistical programming efforts in clinical trials. Collaborate with cross-functional teams to analyze and report clinical data, ensuring compliance with industry stan...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $150K *

Champion strategic IT staffing initiatives and lead a team of recruiters to optimize non-clinical recruiting processes, improve performance metrics, and enhance client satisfaction across various prof...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Staffing

$142K - $195K *

Shape the future of AI-driven software delivery by leading transformative initiatives across IT disciplines, enhancing productivity, and fostering a culture of collaboration and innovation in a dynami...

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$76K - $131K *

Join a team that's redefining healthcare compliance by leading detailed coding audits, mentoring auditors, and driving innovative solutions to enhance compliance and operational excellence in a dynami...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$93K - $97K *

Contribute to program success by supporting planning, execution, and management of projects. Analyze data, prepare reports, and optimize resources to ensure objectives are met within scope, time, and...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Join a team that's dedicated to transforming healthcare data solutions. As a Senior Data Engineer, you'll enhance complex systems, collaborate across departments, and drive analytics to optimize finan...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $145K *

Elevate healthcare through strategic AI product management, driving innovation and lifecycle management of AI solutions. Collaborate cross-functionally to align business objectives with customer needs...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$46K - $131K *

Join a team that's dedicated to enhancing customer service and operational efficiency. Lead initiatives in finance operations, manage complex reporting, and build strong client relationships while dri...

Louisville, KYRemote

2 days ago

  •   Less than 5 years exp.  •   Business Services

$94K - $107K *

Transform data governance operations by driving process adoption, supporting data stewards, and enhancing governance tools. Collaborate with teams to ensure compliance, improve workflows, and leverage...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $110K *

Empower quality assurance by overseeing clinical audits, ensuring accuracy and consistency. Collaborate with auditors to enhance performance, mentor teams, and drive process improvements in a remote e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$90K - $115K *

Lead the charge in transforming complex business needs into impactful analytic products. Collaborate with stakeholders to design, develop, and maintain reusable semantic models that enhance decision-m...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$100K - $120K *

Elevate clinical research by assisting with study design, medical monitoring, and compliance to ensure effective execution of clinical trials and contribute positively to patient outcomes in alignment...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$77K - $202K *

Elevate your career by supporting risk and compliance in healthcare. As a Senior Associate, you'll analyze complex issues, manage client engagements, and guide junior team members while enhancing your...

2 weeks ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Lead the charge in directing departmental activities, optimizing resources, and achieving goals in a dynamic healthcare environment. Foster growth and compliance while ensuring high standards of servi...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Inspire data-driven decision-making as you lead analytics and predictive modeling efforts. Collaborate across teams to enhance patient engagement, forecast demand, and measure impact, driving strategi...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$60K - $129K *

Transform behavioral healthcare for children by utilizing clinical expertise to assess and enhance care plans, ensuring effective and culturally competent support that promotes optimal outcomes and re...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$73K - $110K *

Shape the future of coding quality by overseeing audits, developing guidance, and collaborating with teams to enhance accuracy and compliance in healthcare coding practices...

RemoteRemote

2 days ago

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Support clinical studies by assisting with scientific conduct, data reconciliation, and protocol management. Engage with stakeholders to ensure compliance and operational excellence across multiple st...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive clinical innovation by supporting the operational delivery of pivotal studies, collaborating cross-functionally, and ensuring compliance with industry standards. Play a key role in the medical m...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Shape the future of healthcare technology by leading enterprise architecture initiatives. Collaborate with business and tech leaders to align strategies, drive modernization, and ensure technology inv...

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$106K - $147K *

Shape the future of healthcare technology by evaluating application portfolios to support strategic mergers and acquisitions. Collaborate with cross-functional teams to define integration strategies a...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $127K *

Innovate with us to enhance data protection strategies, ensuring robust security and compliance across diverse platforms. Collaborate on complex projects, troubleshoot incidents, and drive improvement...

RemoteRemote

6 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Kentucky?question toggle

    Kentucky listings may include senior and experienced roles in areas such as healthcare, manufacturing, logistics, finance, technology, sales, engineering, and operations. Available positions vary by employer and location.

  • Which Kentucky cities have professional job opportunities?question toggle

    Opportunities may be found in Louisville, Lexington, Bowling Green, and communities throughout the state. Search by location to explore current openings near you.

  • Do jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with advertised salaries of $100,000 or more. Review each listing for its specific compensation details and requirements.

  • How can I find a high-paying job in Kentucky?question toggle

    Search Kentucky listings by city, role, or industry, then review the qualifications and compensation details. Tailor your resume to the position and emphasize relevant accomplishments and leadership experience.