Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$250K - $300K *

Join our team to develop essential general surgical practices that improve patient care, working with a collaborative team while enjoying a balanced lifestyle, including shared call and coverage of ju...

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$130K - $140K *

Elevate your career by joining a dynamic sales team driving colorectal cancer screening solutions. Engage healthcare professionals, provide education, and strategize business growth across a vibrant t...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$149K - $224K *

Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$198K - $297K *

Champion utilization management by conducting patient reviews, collaborating with medical staff, and leading initiatives to enhance compliance and efficiency. Drive results through effective communica...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$210K - $250K *

Deliver comprehensive case reviews and clinical guidance, ensuring regulatory compliance and optimal patient outcomes. Collaborate with healthcare teams across multiple states to enhance service quali...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$166K - $200K *

Join a team that's dedicated to providing exceptional primary care to Veterans. This role involves comprehensive patient assessments, diagnostics, and collaboration within a multi-disciplinary team to...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Empower a high-performing sales team to drive strategic growth and customer engagement in the biopharma sector. Lead complex sales initiatives, build executive relationships, and translate business st...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance the adoption of cutting-edge prostate cancer imaging solutions while leading site activations, enhancing workflows, and ensuring optimal product utilization in the oncology sector, supporting...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$73K - $98K *

Join a team that's dedicated to excellence in DRG auditing. Leverage your expertise in MS-DRG and APR-DRG coding to ensure accuracy and compliance while working remotely. Enjoy a collaborative environ...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Business Services

$221K - $335K *

Elevate clinical research by leading innovative studies, ensuring data integrity and patient safety. Collaborate cross-functionally to drive strategic initiatives and enhance clinical development whil...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$108K - $149K *

Advance the organization by establishing robust data and AI governance practices. Collaborate across teams to ensure compliance, integrity, and responsible usage of data and AI assets, supporting both...

United StatesRemote

Reposted 6 days ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $220K *

Contribute to patient care by evaluating and managing pain issues using a multimodal approach. Collaborate with medical staff, maintain records, and ensure compliance with healthcare standards while p...

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a team that's dedicated to enhancing healthcare delivery and outcomes. Lead the Acute Care and Specialties service line, overseeing clinical and administrative operations while ensuring quality c...

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$175K - $210K *

Champion the execution of a comprehensive medical affairs plan for renal cancer theranostics, driving cross-functional alignment and strategic initiatives to enhance patient outcomes and advance clini...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$198K - $297K *

Engage in a dynamic role that empowers team collaboration and drives results in a leading organization recognized for innovation and excellence in performance, fostering an environment of growth and p...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$156K - $235K *

Accelerate your career by leading Theranostics initiatives within a national healthcare advisory team. Collaborate with executives to enhance patient outcomes and operational performance through strat...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$180K - $220K *

Unlock potential in a supportive endodontic practice, collaborating with experienced professionals while providing comprehensive care. Enjoy mentorship and a clear path to partnership in a patient-foc...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Pioneer a patient-centered endodontic practice, leveraging advanced technology and mentorship to deliver exceptional care while fostering relationships with local dentists and enjoying a supportive te...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join an established endodontic practice focused on patient care and advanced technology. Contribute your expertise in a supportive environment with mentorship opportunities and a clear path to partner...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Join a dynamic endodontic practice focused on advanced tooth-saving care. Collaborate with a supportive team, treat diverse cases, and enjoy a clear path to partnership while enhancing patient outcome...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Champion patient-centered endodontic care, utilizing advanced technology and mentorship. Join a collaborative team focused on preserving natural teeth and providing timely, compassionate treatment in...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $220K *

Develop your endodontic expertise in a patient-centered practice, collaborating with general dentists and utilizing advanced technology for precise treatment. Enjoy mentorship opportunities and a clea...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $500K *

Transform patient care by leading wound care initiatives in skilled nursing facilities. Enjoy a no-call lifestyle with flexible scheduling, clinical autonomy, and the opportunity to make a lasting imp...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$250K - $275K *

Join us to lead clinical operations for a multi-state virtual care team, ensuring high-quality, timely care. This role combines direct patient care, administrative leadership, and strategic oversight...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.