Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Senior Manager, Lifecycle Marketing
$160K - $190K *
Join us to lead the owner lifecycle marketing strategy, optimizing journeys and communications across multiple channels. You'll drive engagement and retention, ensuring a seamless experience from init...
3 weeks ago
Senior Technical Program Manager
$130K - $150K *
Lead the charge in driving program delivery and portfolio management for a dynamic Security team, ensuring effective execution of enterprise initiatives while fostering cross-functional collaboration...
1 week ago
$125K - $150K *
Join a dynamic team to drive innovation and lead the transformation of complex systems into scalable, API-first solutions. As an Engineering Manager, you'll foster growth among engineers, ensuring qua...
Reposted 1 month ago
Senior Product Manager - Identity Inventory, Correlation and Graph
$125K - $150K *
Champion the evolution of identity security by leading product management for our core identity graph and correlation services, ensuring seamless integration and access control across platforms while...
3 weeks ago
$242K - $303K *
Join as the primary privacy leader to manage and enhance an enterprise-wide privacy program while navigating complex regulations. Collaborate across departments to drive compliance, innovation, and ef...
Reposted 3 weeks ago
Senior Manager, Contract Manufacturing
$138K - $145K *
Transform your career by overseeing contract manufacturing operations, ensuring quality and efficiency across diverse product formats. Collaborate with cross-functional teams to drive improvements and...
4 days ago
Project Manager - Field Service
$90K - $110K *
Pioneer procurement excellence by managing supplier relationships and project timelines, while ensuring the effective acquisition of resources for seamless operations and continuous supply chain impro...
Reposted 3 weeks ago
$110K - $130K *
Elevate client success by leading complex implementations, managing technical integrations, and driving process improvements. Utilize AI tools to enhance efficiency while collaborating with cross-func...
5 days ago
$101K - $157K *
Shape the future of BIM projects by leading a dynamic team, optimizing processes, and ensuring client satisfaction through effective management and strategic input across all phases of electrical cons...
2 weeks ago
$250K - $300K *
Accelerate progress at a forward-thinking company by leading a dynamic engineering team, fostering a culture of excellence while delivering innovative product features and driving technical growth. Co...
Reposted 3 weeks ago
Senior Manager, REMS Operations
$141K - $212K *
Deliver strategic oversight and operational management for FDA-mandated REMS programs, ensuring compliance, governance, and collaboration across teams and vendors to enhance program effectiveness and...
3 weeks ago
$140K - $185K *
Unlock the power of enterprise data as you design and implement Master Data Management solutions that enhance healthcare operations, drive analytics, and enable AI-driven decision-making with trusted...
Reposted 2 weeks ago
Senior Manager, Revenue Accounting
$107K - $153K *
Transform revenue recognition processes by leading the review of complex customer contracts, ensuring compliance with ASC 606 while driving automation and accuracy in accounting operations with impact...
Reposted 3 weeks ago
$95K - $115K *
Lead the charge in expanding business across the Northeast U.S. and Canada by building strategic partnerships, managing client relationships, and driving sales growth through innovative packaging solu...
6 days ago
$97K - $132K *
Shape impactful educational proposals by leading RFP responses and submissions. Collaborate across teams to craft persuasive narratives and ensure compliance, driving state approvals and district awar...
3 weeks ago
Senior Portfolio & Project Controls Analyst
$83K - $120K *
Accelerate renewable energy initiatives by leading complex analytics and optimizing portfolio performance. Drive strategic decision-making through advanced BI tools and mentoring while establishing ro...
Reposted 3 weeks ago
$105K - $130K *
Join a dynamic team to lead multiple client engagements, driving innovative solutions and strategic direction. Foster cross-functional collaboration in a fast-paced environment with a focus on deliver...
Reposted 1 week ago
$110K - $130K *
Lead the creative vision and execution of impactful design assets, enhancing brand identity and streamlining production processes using AI tools. Collaborate across teams to deliver high-quality marke...
2 weeks ago
Implementation Manager - Data Solutions
$91K - $145K *
Shape the future of data solutions by leading complex pharmacy claims and physician-level data integrations. Collaborate with cross-functional teams to deliver high-quality, scalable solutions that me...
2 weeks ago
$104K - $174K *
Unlock potential by driving client engagement and delivering tailored solutions. Collaborate with cross-functional teams to enhance client experiences, manage complex projects, and present insights to...
3 weeks ago
$120K - $145K *
Join a dynamic team to lead product strategy and innovation for cutting-edge cloud solutions, driving customer-centric development and measurable growth within the legal technology space. Shape the fu...
Reposted 2 weeks ago
$140K - $150K *
Manage and grow CPG and Grocery client portfolios by identifying expansion opportunities, nurturing key relationships, and executing strategic plans for revenue retention and growth while collaboratin...
Reposted yesterday
Director, Pricing and Profitability
$124K - $223K *
Shape the future of pricing strategy by leading a dynamic team to optimize profitability and drive strategic decisions across SaaS and services. Collaborate with executives to enhance customer value a...
2 weeks ago
$80K - $95K *
Join a dynamic team to enhance decision-making and support EHRM initiatives. Drive program management, facilitate stakeholder engagement, and contribute to strategic communications while ensuring effe...
3 weeks ago
Director of Applied AI Engineering
$207K - $290K *
Elevate your career by leading a dynamic Applied AI team, transforming innovative AI solutions into production-ready systems within a regulated financial environment, while collaborating across depart...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.