Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Project Management Jobs in South Dakota

Sort By: Relevance

$160K - $190K *

Join a team that's driving architectural excellence and AI adoption. You'll optimize cloud systems, enhance data processing, and lead engineering teams to innovate and scale efficiently, ensuring robu...

United StatesRemote

3 weeks ago

  •   11 - 15 years exp.  •   Enterprise Technology

$110K - $130K *

Elevate customer success in the Americas by leading a growing team of CSMs. Drive adoption, value realization, and customer health while shaping playbooks and strategies for scalable growth. Collabora...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $145K *

Transform the data platform by owning product direction and delivery. Collaborate across teams to prioritize needs, streamline processes, and ensure engineering focuses on impactful projects while enh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Champion project accounting excellence by leading Oracle Fusion PPM migrations. Collaborate with cross-functional teams to drive successful implementations and optimize processes, ensuring alignment w...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$270K - $365K *

Lead a dynamic engineering organization to transform offensive capabilities into proactive defense. Shape strategy, scale teams, and deliver innovative solutions across multiple pillars, ensuring robu...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Information Technology

$92K - $120K *

Lead a dynamic team of Client Contract Managers to optimize renewal strategies, drive retention, and enhance operational excellence through effective leadership and cross-functional collaboration. Ele...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$117K - $160K *

Elevate your career by leading operations for a dynamic Customer Order team. Drive strategic initiatives, foster collaboration, and enhance workflows to improve efficiency while ensuring exceptional p...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $148K *

Shape the future of clinical documentation by leading a dynamic team to enhance integrity, performance, and compliance in healthcare settings, while collaborating with stakeholders to drive optimal re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Business Services

$140K - $185K *

Elevate project success by leading commissioning efforts, managing field teams, and ensuring timely execution of complex projects. Utilize advanced decision-making and client interaction skills to dri...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Technical Services

$64K - $102K *

Champion impactful construction projects across healthcare facilities, overseeing all phases from design to occupancy. Collaborate with stakeholders to ensure compliance, budget adherence, and timely...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Lead the charge in enabling a high-performing delivery team within a technical ecosystem. Drive agile practices, ensure effective sprint management, and facilitate collaboration among engineering, arc...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Innovate and manage large-scale commercial programs, driving cross-functional alignment and revenue growth. Lead end-to-end program development, ensuring operational excellence and strategic execution...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in defining and executing critical technical programs, enhancing research infrastructure while ensuring impactful collaboration across teams. Empower researchers to translate their wor...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$185K - $210K *

Lead and optimize global technology services across Adobe and Salesforce ecosystems. Drive strategic direction, client delivery, and team growth in a fast-paced environment. Champion technical excelle...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $140K *

Join a dynamic team to foster client relationships, drive strategic growth, and innovate solutions that enhance client success. Collaborate across functions to deliver impactful results and maintain i...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Media

$132K - $165K *

Accelerate progress at multi-site data center and AI programs valued over $25M. Lead diverse teams to ensure successful delivery, budget management, and customer satisfaction while driving executive c...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$107K - $171K *

Shape the market narrative for AI Agent Identity by leading product marketing initiatives. Own positioning, messaging, and commercial enablement for DNSid, translating complex innovations into compell...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Information Technology

$80K - $95K *

Transform airport advertising environments by conducting site visits, developing signage concepts, and collaborating with design teams. This role combines hands-on fieldwork with creative design to en...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Media

$182K - $250K *

Champion market development strategies to enhance our presence in CMS and HHS. Leverage your expertise to build relationships, identify opportunities, and drive impactful outcomes in federal health IT...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$130K - $150K *

Drive impactful solutions as a Healthcare Technology Manager, optimizing Epic Patient Access systems. Collaborate with clients and teams to enhance workflows and deliver sustainable results in a suppo...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$125K - $150K *

Unlock your potential by leading the development of innovative DRGV services, enhancing billing and coding optimization. Collaborate across teams to create scalable solutions that drive operational ex...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$198K - $233K *

Lead the charge in developing a robust content management system to enhance cross-functional workflows and publishing capabilities, fostering a high-performing engineering team dedicated to scalabilit...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$130K - $150K *

Unlock potential by leading the People Technology & Operations team, optimizing systems like Workday, and driving automation and AI solutions to enhance the employee experience and streamline operatio...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $160K *

Drive the future of structural engineering by leading complex capital projects, mentoring junior staff, and ensuring technical excellence across diverse markets, particularly in healthcare. Collaborat...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$145K - $175K *

Engage as a strategic HR partner in a global, fast-paced tech environment, supporting product and engineering teams through organizational design, talent strategy, and leadership development to naviga...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.