Explore $100K+ Jobs in South Dakota

Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.

South Dakota career opportunities

South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.

Where to find jobs

Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.

Find the right role on Ladders

Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.

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1,000+

Director, Project Management Jobs in South Dakota

Sort By: Relevance

$125K - $155K *

Innovate product strategy and execution, bridging cross-functional teams to deliver impactful solutions that align with customer needs and organizational goals throughout the product lifecycle...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $150K *

Unlock potential by overseeing project operations and client relationships, driving growth through strategic partnerships and best practices. Lead teams to achieve business goals while ensuring high s...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$95K - $110K *

Drive successful project implementations and build client relationships by managing multiple initiatives. Oversee planning and execution, ensuring deliverables meet budget and quality standards while...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$115K - $120K *

Lead the charge in driving operational excellence and strategic enablement across global Inside Sales teams, enhancing commercial effectiveness and delivering exceptional client value through innovati...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $150K *

Empower the development of innovative banking solutions by driving product strategy, collaborating across teams, and delivering scalable capabilities that enhance customer experiences and meet busines...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $180K *

Transform the digital manufacturing landscape by driving sales growth and market expansion. Collaborate across teams to develop strategies, support federal opportunities, and enhance customer value th...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $140K *

Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$86K - $124K *

Champion the future of project management by leading SAP initiatives, driving agile practices, and delivering innovative solutions that meet client needs while fostering team collaboration and continu...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Collaborate with cross-functional teams to enhance Salesforce solutions, driving process improvements and operational excellence. Contribute hands-on to configuration, data management, and user adopti...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Pioneer a data-driven future by leading product strategy for data science solutions. Drive innovation, oversee development, and ensure alignment with business goals to deliver impactful analytics prod...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $150K *

Lead the charge in defining and executing product strategies for Benefits, collaborating with cross-functional teams to drive innovation and deliver customer value through data-driven insights and aut...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $195K *

Drive the development and execution of strategic projects for radioisotope production facilities. You will lead cross-functional teams to ensure operational readiness, regulatory compliance, and succe...

RemoteRemote

Reposted 4 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Drive mobile engineering excellence across diverse product teams, ensuring strategic direction, fostering collaboration, and enhancing delivery. Lead managers, shape architecture, and cultivate a prod...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $140K *

Transform your career by leading complex design change projects from inception to execution. Collaborate with cross-functional teams, manage substantial budgets, and drive innovation in a fast-paced e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Join a team that's dedicated to delivering successful projects on time and on budget. As a key player, you'll drive project planning, coordinate with stakeholders, and ensure effective communication t...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$500K+*

Lead the transformation of media ingestion and distribution systems, driving automated, AI-powered workflows that enhance efficiency and accelerate content delivery to a global audience. Collaborate a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$100K - $130K *

Drive your career forward by leading federal proposal efforts from start to finish. Collaborate with cross-functional teams to create compelling, compliant proposals for defense and civilian sectors...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Lead the charge in software innovation while mentoring a high-performing engineering team. Drive technical solutions and ensure project success through hands-on involvement, fostering a culture of con...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$144K - $180K *

Lead product strategy and outcomes across diverse portfolios, driving team success and aligning customer needs with business objectives. Foster collaboration across functions to deliver impactful prod...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Transform risk management by leading a national team focused on claims, clinical risk reduction, and innovative AI solutions to improve outcomes. Drive strategic oversight and implement best practices...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$126K - $202K *

Lead impactful initiatives by analyzing data and building tools that drive revenue growth. Collaborate with product teams to identify gaps, streamline processes, and enhance enterprise readiness, ensu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $225K *

Oversee complex industrial construction projects, ensuring safety, quality, and timely completion. Lead multidisciplinary teams, manage contractor performance, and coordinate with stakeholders to achi...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Real Estate & Construction

$92K - $124K *

Partner with us to enhance legal operations and implement eDiscovery processes. You'll lead customer data privacy initiatives, improving cross-functional collaboration and response strategies for comp...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$115K - $130K *

Engage with stakeholders to drive product strategy and enhance the Affordable Equity platform. Collaborate with teams to translate user needs into actionable solutions, ensuring timely delivery and al...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$120K - $145K *

Pioneer cross-functional programs, managing teams to deliver crucial initiatives. Drive alignment across departments, enhance operational excellence, and elevate program delivery practices while track...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs are available in South Dakota?question toggle

    Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.

  • Which South Dakota cities have professional job opportunities?question toggle

    Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.

  • How can I find high-paying jobs in South Dakota?question toggle

    Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.

  • Do South Dakota jobs listed on Ladders all pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.