Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
Principal Technical Product Manager
$138K - $165K *
Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...
5 days ago
$85K - $105K *
Lead the charge in managing enterprise-level projects, ensuring timely delivery and alignment with business goals. Collaborate across teams to optimize processes and guide clients through complex soft...
4 weeks ago
Senior Project Control Analyst
$95K - $115K *
Drive financial governance by tracking budgets, analyzing variances, and generating reports in a federal mission environment. Collaborate with cross-functional teams to ensure compliance and support e...
1 week ago
$108K - $162K *
Deliver exceptional customer service by managing maintenance operations and support activities. Collaborate with teams to ensure timely resolution of issues while leading talent development and execut...
2 days ago
Senior Manager, Clinical Lab Project Management
$134K - $219K *
Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...
2 weeks ago
Associate Director, Strategy & Operations
$179K - $248K *
Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...
2 weeks ago
Technical Program Manager, Industrial Controls, R&D
$144K - $211K *
Lead the charge in managing complex Industrial Controls workstreams, ensuring seamless execution of NPI programs. Collaborate across teams to deliver innovative automation solutions on time and within...
2 days ago
Senior Manager, Technical Program Management
$135K - $160K *
Lead the charge in shaping a new Technical Program Management team, guiding TPMs to deliver impactful results while fostering collaboration across Engineering and Product. Drive strategic planning and...
2 weeks ago
Senior AV Project Manager (Systems Integration)
$90K - $110K *
Help us drive project success by managing AV integration projects from inception to completion, ensuring timely delivery, budget adherence, and client satisfaction while fostering collaboration within...
2 days ago
Director, Technical Program Management
$209K - $239K *
Drive complex technical initiatives and lead multi-year integration strategies to enhance platform capabilities, ensuring alignment with business objectives and fostering a culture of excellence in Te...
3 weeks ago
Supervisor - Program Management
$80K - $95K *
Drive operational excellence by overseeing program management activities, supervising a dedicated team, and ensuring adherence to policies and procedures. Collaborate with stakeholders to enhance effi...
2 weeks ago
Oracle EPM Senior Project Manager
$120K - $145K *
Lead Oracle Cloud EPM projects, ensuring timely delivery and high quality. Collaborate with stakeholders and manage resources to achieve project objectives, fostering team success and effective commun...
Reposted 1 week ago
Principal Product Manager, Lighthouse
$275K - $300K *
Transform customer experiences by leading the multi-location product initiative, driving strategy, and developing innovative solutions that scale across the platform for diverse users, empowering them...
Reposted 3 weeks ago
$100K - $120K *
Unlock your potential as a Project Manager, leading complex, cross-functional projects. Oversee multiple initiatives, ensuring timely delivery and budget adherence while mentoring team members and enh...
1 week ago
$110K - $130K *
Shape the future of education by owning content strategy for assessments. Collaborate with experts and district leaders to enhance quality and drive adoption, leveraging insights to inform product dir...
2 days ago
$221K - $260K *
Lead the execution of multi-facility clean energy campuses, overseeing complex solar, wind, and battery projects. Collaborate with diverse teams to ensure operational excellence and strategic alignmen...
1 week ago
$120K - $145K *
Lead a dynamic team of software engineers to enhance data import systems, ensuring efficient document processing and integration. Drive technical direction, improve engineering practices, and foster a...
2 weeks ago
$150K - $180K *
Pioneer the preconstruction process for a major data center campus, guiding it from design through procurement and ensuring alignment with budget and schedule goals. Lead a team, set standards, and in...
4 weeks ago
Manager/Director, Talent Management
$130K - $170K *
Join a team that's advancing enterprise talent strategy through data-driven performance management, succession planning, and organizational effectiveness, partnering with leaders to build high-perform...
2 weeks ago
$85K - $100K *
Transform product initiatives by driving the Product Development Lifecycle, ensuring clarity and momentum across functions while empowering teams to focus on their expertise and decisions...
1 week ago
$180K - $210K *
Elevate creative excellence by leading a multidisciplinary team, setting vision and quality standards, and driving impactful brand strategies across diverse channels in a dynamic healthcare environmen...
2 weeks ago
$110K - $130K *
Lead the charge in managing complex public safety projects, ensuring timely delivery and high customer satisfaction. Oversee a diverse portfolio while collaborating with cross-functional teams to driv...
1 week ago
$131K - $237K *
Lead the charge in managing complex IT programs, ensuring product development and lifecycle management while coordinating multiple vendors and teams to meet customer needs and deliver on strategic obj...
3 days ago
$88K - $154K *
Join a dynamic team as a Document Control Supervisor, overseeing document management for construction and engineering projects. Drive process improvements, ensure compliance, and support project teams...
3 weeks ago
Senior Manager, Stop-Loss Risk and Proposals
$110K - $130K *
Take ownership of the sales process for self-funded stop-loss cases, evaluating risk, managing proposals, and collaborating with underwriters to enhance case preparation and market success...
1 week ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.