Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$99K - $124K *

Innovate and elevate our technology landscape by leading a talented IT team to deliver powerful software solutions, ensuring top-notch quality and security while meeting global needs through agile met...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$173K - $272K *

Transform digital tech transfer and knowledge management by leading a multi-disciplinary team to enhance manufacturing capabilities, ensuring seamless integration of process knowledge and data-driven...

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$70K - $140K *

Lead the charge in enhancing our Partner ecosystem by managing relationships and driving growth initiatives. Oversee onboarding, operations, and support for System Integrators while implementing autom...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$135K - $160K *

Drive innovation in payments technology by leading technical direction, designing scalable solutions, and mentoring teams. Blend hands-on development with strategic architecture to enhance system perf...

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Take ownership of payroll operations, ensuring accuracy and compliance while leading a team to deliver timely wage payments and manage tax obligations effectively across the organization...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $140K *

Shape the future of federal financial operations by driving user adoption and change management for a new tool. Collaborate with stakeholders to enhance user experience, streamline processes, and ensu...

United StatesRemote

5 days ago

  •   5 - 7 years exp.  •   Information Technology

$181K - $225K *

Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$181K - $225K *

Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$170K - $243K *

Transform product innovation by leading AI-driven strategies and experiments, collaborating across teams to enhance software solutions and improve employee experiences in a dynamic, fast-paced environ...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Collaborate with senior leadership to strategically manage real estate and facilities. Drive operational efficiency, ensure regulatory compliance, and oversee lease lifecycle management to support bus...

1 week ago

  •   5 - 7 years exp.  •   Transportation

$170K - $190K *

Join a team that's redefining live experiences by leading high-volume, quick-turn activations. Drive production excellence from concept to execution, ensuring quality and safety while managing multipl...

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$170K - $190K *

Transform live experiences by leading high-volume, quick-turn activations. Drive production excellence from concept to execution, ensuring quality, safety, and budget adherence while managing multiple...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$150K - $190K *

Transform financial management by leading analysis, forecasting, and reporting to achieve revenue and profit goals. Collaborate with business leadership to drive performance and maintain compliance wi...

Reposted 4 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that leads heavy civil construction estimating, shaping budgets and bid strategies for major projects. Oversee processes, manage a skilled team, and foster best practices for competitive s...

3 weeks ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Lead the charge in managing a dynamic division, overseeing strategic and operational excellence while fostering team development and customer satisfaction. Drive growth initiatives and ensure effectiv...

3 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$150K - $180K *

Unlock new opportunities as you drive business growth in the life sciences sector. Focus on building relationships and matching client needs with innovative solutions in commercial consulting, brand c...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$125K - $172K *

Unlock potential by leading product initiatives for 360e Facility Coding, collaborating with diverse teams to enhance customer experiences and drive business value through innovative solutions and eff...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$208K - $306K *

Join a team that's redefining engineering excellence by leading platform services that enhance software development. Drive innovation, consolidate capabilities, and foster a culture of collaboration t...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$80K - $95K *

Champion innovative land development projects by collaborating with clients and teams, managing site designs, and ensuring compliance with regulations. Engage in all phases from planning to execution...

3 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$168K - $253K *

Contribute to shaping the future of Industrial Automation by leading strategic initiatives, translating market insights into actionable recommendations, and collaborating with cross-functional teams t...

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's enhancing our Enterprise Risk Management Framework. Collaborate across the organization to identify, assess, and manage risks while promoting accountability and improving risk manag...

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$80K - $95K *

Unlock potential by leading diverse industrial and infrastructure projects. Collaborate with multidisciplinary teams to enhance project delivery, client relationships, and strategic planning while adv...

4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$125K - $185K *

Transform strategic sourcing for HR and Benefits, leading complex engagements and driving cost savings while ensuring high supplier performance and stakeholder satisfaction across diverse client needs...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Business Services

$183K - $215K *

Shape the future of North American inland transportation by leading product strategy and development. Collaborate with cross-functional teams to deliver actionable insights and drive market success in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$250K - $275K *

Empower the data landscape by leading a team to create reliable, AI-ready data systems. Own the data platform, establish governance, and ensure data quality for impactful decision-making across client...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.