Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$223K - $233K *

Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$165K - $175K *

Empower progress at the forefront of data product management, leading the development of innovative solutions. Drive product success through strategic oversight, client engagement, and cross-functiona...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $125K *

Elevate product strategy and delivery by leading a multidisciplinary team to ensure alignment with stakeholder needs and mission-critical outcomes in a fully remote environment...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$88K - $147K *

Oversee project financial performance and analytics, ensuring effective management across complex contracts. Collaborate with teams to enhance processes and deliver actionable insights, driving operat...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$73K - $130K *

Drive the acquisition and usability of clinical data to enhance healthcare outcomes. Collaborate with diverse teams to analyze data gaps, implement integrations, and optimize processes, ensuring timel...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Join a team that's dedicated to optimizing client business processes through analysis and collaboration. You'll facilitate benchmarking studies, document system customizations, and support solution im...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$125K - $150K *

Grow your career with a strategic leadership role driving product vision, innovation, and profitability. Collaborate across teams to enhance product lifecycle management and market strategies, ensurin...

1 week ago

  •   8 - 10 years exp.  •   Telecommunications & Hardware

$88K - $105K *

Lead the charge in managing cross-functional product development projects, ensuring timely execution and budget adherence while coordinating global teams and stakeholders throughout the entire product...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$70K - $95K *

Deliver impactful project management for complex implementations, leading teams to ensure successful outcomes while cultivating valued client relationships and driving business success through effecti...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$235K - $265K *

Champion product innovation by leading a dynamic team to define strategy, drive decisions, and ensure successful launches that align with company growth and customer needs in the health technology sec...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading a team in Decision Sciences, driving analytics and insights for marketing success. Collaborate with stakeholders to deliver high-quality performance measurement and data-dr...

Yesterday

  •   5 - 7 years exp.  •   Media

$100K - $120K *

Transform the employee experience by leading impactful HR initiatives, managing events, and enhancing organizational culture. Collaborate across teams to drive engagement, support leadership developme...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$87K - $116K *

Join a dynamic team to develop operational strategies and lead a branch, enhancing customer satisfaction and driving sales growth while training to manage diverse teams and projects effectively...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

$88K - $105K *

Lead the charge in construction materials testing projects from start to finish, ensuring technical quality, client satisfaction, and financial health while mentoring staff and expanding client relati...

1 month ago

  •   5 - 7 years exp.  •   Business Services

$140K - $150K *

Reimagine data management as a Senior Technical Product Owner, leading cross-functional teams to drive product vision and execution. Oversee complex SQL Server systems and cloud-native applications, e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Lead the charge in technical project management for energy initiatives. Oversee installations, ensure quality, and drive projects from kickoff to completion while building critical partnerships and im...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Energy & Utilities

$80K - $95K *

Take ownership of strategic financial analyses and M&A activities to drive growth, evaluate investment opportunities, and support post-acquisition integration for organizational success and alignment...

Reposted 2 days ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Transform the training landscape for revenue teams by developing impactful learning programs that drive sales performance, enhance retention, and foster leadership growth. Collaborate with cross-funct...

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$130K - $160K *

Drive operational excellence by leading a global team to deliver high-quality wellbeing programs. Collaborate with stakeholders to ensure effective execution, maintain standards, and enhance participa...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$173K - $255K *

Empower global expansion by leading customer operations strategy, managing complex programs, and driving continuous improvement across international markets. Collaborate with cross-functional teams to...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$85K - $95K *

Transform client relationships by leading strategic projects, ensuring quality and alignment across teams. Collaborate with stakeholders to drive success and meet client expectations while fostering g...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Transform investment research by evaluating and integrating diverse datasets, enhancing AI-driven workflows, and driving strategic content initiatives to elevate platform value and user experience...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Consumer Technology

$115K - $168K *

Lead the charge in federal grant management for the 988 Suicide & Crisis Lifeline, overseeing compliance, budgeting, and operations. Collaborate across teams to ensure effective grant administration a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$200K - $300K *

Join a dynamic team to manage bank capital relationships, drive coverage strategies, and support capital formation initiatives. This role offers growth opportunities in a fast-paced environment, focus...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$183K - $228K *

Drive strategic financial insights as a key partner to the go-to-market teams, owning revenue forecasts and investment economics. Collaborate with leadership to shape long-term growth strategies and e...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.