Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Director, Product - State & Local Government
$176K - $264K *
Champion innovative strategies for State & Local Government, bridging customer needs with product development. Drive revenue growth and enhance customer relationships through industry insights and tai...
Reposted 2 days ago
$110K - $130K *
Champion innovative engineering solutions by leading multi-site projects, enhancing infrastructure, and driving operational improvements to ensure safety and efficiency across facilities...
3 weeks ago
$190K - $220K *
Champion financial excellence by leading a dynamic team, driving strategic analysis, and leveraging AI to enhance decision-making for a diverse portfolio of clients in a fast-paced, remote environment...
1 week ago
Senior Manager, Clinical Data Management, Study Lead
$134K - $219K *
Empower data management excellence by leading cross-functional teams, ensuring compliance, and driving process improvements across multiple clinical trials while mentoring staff and maintaining high d...
4 days ago
$115K - $161K *
Lead procurement efforts for a major capital project, managing sourcing, contracts, and supplier performance. Collaborate with cross-functional teams to ensure project success and compliance throughou...
3 weeks ago
$150K - $160K *
Drive project success by managing integrated delivery across AI task orders, overseeing multidisciplinary teams, and ensuring adherence to quality standards while maintaining project roadmaps and sche...
2 weeks ago
Project Manager- Professional Services
$110K - $130K *
Lead end-to-end client engagements for complex AI and digital projects, managing multiple implementations while ensuring timely delivery and exceeding client expectations. Collaborate with cross-funct...
1 month ago
Senior Director, Client Growth & Strategy, Federal Civilian
$200K - $250K *
Join a team that's shaping growth strategies for Federal Civilian accounts. Leverage your expertise in federal markets to drive business development, capture opportunities, and enhance customer relati...
2 days ago
$80K - $95K *
Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...
3 days ago
$68K - $102K *
Unlock potential by coordinating customer projects, managing deliveries, and ensuring exceptional service. Collaborate with stakeholders to drive operational efficiency and enhance customer satisfacti...
2 days ago
Senior Director, Client Success
$150K - $180K *
Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...
1 week ago
$134K - $241K *
Engage in the safe and efficient management of large-scale construction projects. Oversee field activities, ensure compliance with safety and environmental standards, and coordinate resources to achie...
3 days ago
Senior Manager, Discovery Operations
$120K - $145K *
Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...
Reposted 3 weeks ago
$150K - $180K *
Lead the charge in construction quality management for a large-scale data center portfolio. Drive the establishment of quality standards, ensure compliance, and oversee a dedicated team of Site Qualit...
4 weeks ago
$110K - $130K *
Drive product innovation by designing AI-enabled workflows that simplify complex insurance operations, ensuring user trust and operational efficiency through close collaboration with engineering and g...
Reposted 3 weeks ago
Third Party Due Diligence Project Manager
$105K - $161K *
Elevate your career by leading cross-functional initiatives in third-party risk management. Collaborate with legal and compliance teams to enhance due diligence processes, ensuring adherence to global...
4 days ago
$108K - $130K *
Champion strategic sourcing initiatives across diverse categories, leading a high-performing team to drive measurable value. Foster partnerships, negotiate with suppliers, and implement innovative sol...
3 weeks ago
Executive Director, Clinical Supply Consulting & Intelligence
$250K - $350K *
Lead the development of a clinical supply consulting practice, combining expertise in forecasting, planning, and optimization to enhance decision-making for sponsors. Drive innovation and commercial g...
1 week ago
Client Director Team Lead, GTS
$158K - $199K *
Lead the charge in driving client success through strategic account management and sales leadership. Cultivate relationships with C-level executives while developing innovative solutions for global ac...
3 weeks ago
Client Director Team Lead, GTS
$158K - $199K *
Lead strategic direction and execution for major global accounts, drive growth, retain clients, and manage a dedicated sales team focused on delivering client value and exploring new business opportun...
1 month ago
$120K - $145K *
Pioneer complex ERP implementations by leading diverse teams, managing risks, and aligning project outcomes with client objectives while ensuring timely, on-budget delivery across multiple projects...
Reposted 3 weeks ago
Senior Manager, Integrated Intelligence
$85K - $105K *
Shape impactful insights through analytics, driving data-informed decisions for healthcare clients. Collaborate with cross-functional teams to enhance marketing performance and audience understanding...
Reposted 1 week ago
$110K - $130K *
Deliver strategic insights and leadership in land acquisition, analyzing opportunities and managing due diligence. Collaborate with stakeholders to optimize project planning and budgeting while mainta...
4 days ago
$82K - $172K *
Champion eDiscovery project management by leading high-visibility initiatives for the DOJ. Collaborate with legal teams to ensure seamless project execution across all EDRM phases, delivering quality...
2 days ago
Associate Medical Director (Promotional Medical Education)
$100K - $125K *
Manage a team of medical writers to develop impactful scientific content, ensuring accuracy and compliance. Collaborate with clients and cross-functional teams to drive medical strategies and delivera...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.