Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$93K - $232K *

Shape the future of clinical research by leading multi-regional trials, ensuring timely delivery and compliance. Collaborate with cross-functional teams and sponsors to drive project success and mento...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Optimize project execution by overseeing financial defense, variance tracking, and reporting processes. Your leadership will ensure compliance, timely billing, and effective cost management across mul...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$225K - $270K *

Lead the charge in Workforce Transformation by measuring AI’s impact, redesigning roles, and shaping skills for the future. Collaborate with cross-functional leaders to anticipate workforce needs and...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Enterprise Technology

$120K - $148K *

Accelerate team performance and delivery by leading software engineers, fostering development, and enhancing organizational effectiveness in a dynamic, remote environment. Drive sustainable practices...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$161K - $190K *

Drive strategic planning and scheduling for large-scale capital programs, focusing on data center delivery. Lead teams, establish best practices, and influence stakeholders to ensure successful projec...

United StatesRemote

4 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$94K - $266K *

Engage with clients to manage Salesforce projects, ensuring timely delivery of cloud solutions. Lead cross-functional teams, facilitate requirements sessions, and maintain strong stakeholder relations...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $185K *

Lead global project management efforts, ensuring timely delivery and quality standards while fostering client relationships and team collaboration. Drive operational excellence in clinical research, p...

Durham, NCRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join our dynamic team to design innovative electrical systems for the biotech and pharma sectors, leveraging your expertise in clean room and laboratory facilities to deliver exceptional engineering s...

1 month ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$138K - $180K *

Shape the future of medical device development by driving project execution, collaboration, and innovation within a dynamic Research & Development team focused on enhancing healthcare outcomes and pat...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$91K - $160K *

Drive impactful water projects by overseeing planning, execution, and optimization. Leverage your project management and engineering expertise to enhance community water systems while ensuring environ...

2 weeks ago

  •   Less than 5 years exp.  •   Real Estate & Construction

$95K - $115K *

Lead the charge in managing transportation design projects, mentoring engineers, and delivering innovative solutions. Collaborate within a dynamic team to meet high standards in highway engineering an...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $166K *

Lead and inspire a dynamic project team to deliver complex construction projects, ensuring financial success and high-quality outcomes while fostering a collaborative and positive work environment...

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$135K - $160K *

Empower customers by automating document management and compliance workflows. As a Senior Product Manager, you'll lead cross-functional teams to enhance security programs, streamline processes, and de...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$195K - $208K *

Reimagine user experiences by leading design for core product features, ensuring seamless integration and customer delight. Collaborate across teams to enhance engagement and trust, shaping the future...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion enablement initiatives across Technical and Sales domains, partnering with experts to define and execute programs. Lead content development, delivery, and continuous improvement efforts to en...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a team that's dedicated to delivering high-quality electrical projects. As a Project Manager, you'll oversee complex Data Center installations, ensuring timely execution and strong client relatio...

1 week ago

  •   Less than 5 years exp.  •   Energy & Utilities

$138K - $165K *

Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Technical Services

$110K - $130K *

Join our team to enhance patient access and streamline operational processes, driving meaningful improvements through data analysis, project management, and collaboration across departments while fost...

North Carolina, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $105K *

Lead the charge in managing enterprise-level projects, ensuring timely delivery and alignment with business goals. Collaborate across teams to optimize processes and guide clients through complex soft...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Drive financial governance by tracking budgets, analyzing variances, and generating reports in a federal mission environment. Collaborate with cross-functional teams to ensure compliance and support e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $105K *

Drive successful AMI deployment projects by coordinating smart meter installations, software integration, and vendor partnerships. Ensure utility modernization through effective project management and...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$134K - $219K *

Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's driving electrical engineering excellence across multiple capital projects. Collaborate with cross-functional teams to ensure project success while adhering to safety and compliance...

6 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$110K - $130K *

Champion operational excellence across a large district, driving revenue growth and client satisfaction while leading diverse teams to achieve financial targets and maintain high standards of service...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$80K - $95K *

Advance construction projects by managing installations, coordinating teams, and ensuring compliance with technical standards. Lead subcontractors, oversee material orders, and drive financial objecti...

1 month ago

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.