Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$140K - $170K *
Champion the go-to-market strategy for streaming advertising, leading a product marketing team to craft compelling messaging and drive revenue growth. Collaborate across departments to ensure alignmen...
3 weeks ago
$88K - $105K *
Unlock potential by leading mechanical and plumbing commissioning efforts, ensuring systems meet project requirements through effective coordination, testing, and client collaboration for successful p...
3 weeks ago
Director, Commerce Strategy & Client Partnerships
$139K - $157K *
Transform client partnerships by leading innovative commerce strategies across major retail platforms. Drive growth through integrated marketing, operational excellence, and creative solutions, ensuri...
3 weeks ago
$90K - $110K *
Engage with clients, driving success in digital campaign execution. Become an expert in programmatic advertising processes, enhancing customer satisfaction through effective communication and collabor...
Reposted 3 weeks ago
$146K - $225K *
Transform vendor performance and customer satisfaction by leading strategic initiatives across a global BPO network. Drive accountability, analyze data, and collaborate cross-functionally to enhance o...
2 weeks ago
Engineering Product Manager - Mobility
$179K - $254K *
Join a team that's driving the future of mobility and IoT! Oversee product lifecycles, collaborate with executives, and navigate complex networks to align cutting-edge solutions with customer needs an...
Reposted 2 weeks ago
$250K - $325K *
Accelerate your career by leading strategic communications and public policy initiatives that shape the future of AI identity and accountability. Drive visibility, influence industry narratives, and b...
1 week ago
Senior Environmental Due Diligence (EDD) Professional
$79K - $153K *
Unlock your potential as a Senior Environmental Due Diligence Professional, leading EDD projects and managing client relationships. Collaborate with a skilled team to deliver high-quality Phase I ESAs...
Reposted today
$140K - $180K *
Unlock potential by leading digital transformation initiatives, leveraging open source and cloud technologies. Collaborate with cross-functional teams to enhance public sector solutions, ensuring clar...
Reposted 2 weeks ago
$88K - $105K *
Lead the charge in managing audit engagements, developing teams, and enhancing client relationships while ensuring compliance with industry standards and delivering exceptional service across all phas...
Yesterday
$85K - $140K *
Transform HR systems by optimizing processes and enhancing technology solutions to meet evolving business needs. Lead projects, ensure data integrity, and drive digitalization initiatives while collab...
Yesterday
Senior Technical Product Manager, IT Service Management
$143K - $169K *
Lead the transition to a modern, AI-native ITSM platform, enhancing service management across teams. Drive employee-centric design, streamline workflows, and ensure seamless integration while maintain...
Reposted 3 weeks ago
$235K - $291K *
Champion strategic leadership across diverse digital and marketing initiatives, guiding cross-disciplinary teams and fostering client relationships to drive impactful solutions and business growth in...
2 weeks ago
$134K - $265K *
Join a dynamic SAP team to lead Revenue Accounting and Reporting solutions, guiding clients through the entire lifecycle from design to deployment. Drive innovation and compliance while mentoring team...
1 week ago
$134K - $265K *
Unlock potential by leading SAP Revenue Accounting and Reporting initiatives, guiding clients through the entire solution lifecycle, from design to deployment, while ensuring compliance with ASC 606 a...
1 week ago
Director of Facilities & Procurement
$110K - $130K *
Drive the safety and efficiency of 100+ schools by managing facilities and procurement. Lead a team, oversee capital planning, negotiate contracts, and ensure operational excellence to create a secure...
1 week ago
Staff Product Manager, Agentic Planning
$168K - $285K *
Elevate the future of software planning by leading a team that integrates human and AI collaboration. Shape product direction, connect work to business priorities, and drive strategic decisions in a d...
Reposted yesterday
Associate Director / Director of Product Management, Signatera Hematologic Oncology (Heme)
$180K - $230K *
Empower innovation by leading product strategy for hematologic malignancies. Collaborate across teams to drive market entry, clinical support, and evidence generation for cutting-edge diagnostics in a...
4 days ago
Digital Product Manager - Billings & Payments
$110K - $181K *
Champion impactful technical product strategies, driving customer and business outcomes by collaborating with diverse stakeholders to prioritize solutions, enhance platform performance, and ensure sea...
Reposted 2 weeks ago
Director, Strategy and Special Projects
$141K - $204K *
Drive strategic growth for DSD by leveraging data, analytics, and tools to enhance operational performance and achieve expansion goals. Collaborate with leadership to support initiatives that elevate...
2 weeks ago
Senior Water/Wastewater Project Manager
$110K - $150K *
Empower growth by leading multidisciplinary teams in the planning, design, and execution of municipal water and wastewater projects, ensuring compliance and fostering client relationships to enhance m...
Yesterday
Construction Project Manager - Mission Critical (Traveling)
$100K - $130K *
Join a team that's dedicated to delivering successful projects through effective management, collaboration, and strategic planning. You'll oversee project teams, budgets, and schedules while ensuring...
2 weeks ago
$144K - $195K *
Innovate and lead the design of identity management solutions, ensuring security and integration across platforms. Collaborate with teams to enhance user experience and manage critical issues in a dyn...
3 weeks ago
Quality Manager, QMS & Process Excellence
$110K - $172K *
Unlock potential by leading the design and deployment of a global Quality Management System, ensuring compliance and operational excellence across multiple aerospace sites while fostering collaboratio...
4 weeks ago
Director, Learning Measurement, Evaluation & Reporting
$119K - $186K *
Champion a data-driven approach to learning effectiveness, enhancing measurement, evaluation, and reporting across diverse learning modalities. Collaborate with cross-functional teams to optimize lear...
5 days ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.