Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
BAS / Controls Assistant Project Manager
$78K - $95K *
Help us support project management in commercial and mission-critical environments. Collaborate with teams to ensure compliance, facilitate communication, and assist in project coordination, all while...
Yesterday
Senior Advisor, Product Line Management, Implementation Services
$176K - $281K *
Empower your career by leading complex service portfolios, driving strategic initiatives, and delivering measurable value through innovative solutions in a dynamic environment. Collaborate across team...
3 days ago
Sr. Technical Delivery Manager - Infrastructure/Data Center (General)
$200K - $220K *
Lead successful outcomes across complex technology programs and large-scale customer environments. Drive governance, manage risks, and facilitate executive relationships while coordinating multiple cr...
Reposted 2 days ago
Director, Global Field Sales Operations
$187K - $257K *
Elevate global sales operations by leading forecasting, pipeline management, and productivity initiatives. Collaborate with sales leaders to enhance clarity and consistency, driving growth through inn...
3 weeks ago
Digital Consulting Senior Manager, Oracle Cloud SCM
$145K - $190K *
Unlock your potential by leading transformative Oracle Cloud Procurement initiatives in healthcare. Engage with clients, mentor teams, and drive impactful solutions while enhancing operational efficie...
2 weeks ago
Director, Order to Cash (Revenue Accounting)
$170K - $210K *
Drive the end-to-end Order-to-Cash function, enhancing processes and leading a high-performing team to optimize revenue operations, billing, and collections while partnering with key departments for s...
Reposted yesterday
Principal QM Automation Engineer
$110K - $130K *
Unlock potential by leading the RPA strategy and AI integration across banking platforms. Drive automation architecture, development, and deployment while mentoring teams and ensuring compliance in a...
3 weeks ago
$70K - $150K *
Develop strategic business relationships to drive revenue growth and enhance customer satisfaction. Utilize market insights to create tailored business plans and ensure profitable account management w...
Reposted yesterday
$236K - $312K *
Join a team that's shaping the future of AAA game production. Lead cross-functional efforts, mentor senior managers, and define strategies to ensure high-quality, narrative-driven experiences across o...
Reposted yesterday
Principal, Strategic Partnerships
$190K - $296K *
Advance strategic partnerships by engaging with top tech companies, driving growth through innovative collaborations. Lead negotiations from inception to launch, ensuring impactful results for family...
Reposted 1 week ago
$95K - $115K *
Lead the charge in optimizing operational activities within the DHMS program, ensuring compliance and driving continuous improvement. Collaborate with stakeholders to implement effective strategies an...
1 week ago
$150K - $205K *
Join a team that's driving M&A success by leading financial strategy, target evaluation, and integration planning. Collaborate with senior leaders to identify opportunities and execute critical phases...
2 weeks ago
Product Manager, Global, Oil-Flooded Compressors
$110K - $130K *
Develop and execute innovative product strategies for a global Oil-Flooded compressor portfolio, driving profitable growth through customer insights and cross-functional collaboration to enhance marke...
Reposted 2 weeks ago
Technical Product Manager (Remote)
$145K - $160K *
Accelerate product development by managing the software lifecycle, collaborating with cross-functional teams, and driving strategic initiatives to enhance user experience and meet stakeholder needs...
2 weeks ago
Technical Product Manager (Remote)
$175K - $190K *
Lead the charge in managing the software development lifecycle for innovative products, leveraging low-code platforms to enhance user experience and drive strategic initiatives across cross-functional...
2 weeks ago
Manager, Professional Services Federal
$128K - $160K *
Drive operational excellence and customer satisfaction by managing services teams, optimizing project delivery, and enhancing client engagement strategies for government clients, ensuring alignment wi...
Reposted 6 days ago
$125K - $150K *
Lead strategic initiatives by coordinating cross-functional teams to drive major partner launches and product developments, ensuring alignment with executive priorities and measurable outcomes for com...
5 days ago
$135K - $160K *
Transform product security by leading strategy, conducting threat modeling, and collaborating across teams to ensure secure design and compliance. Drive innovation in security practices while mentorin...
4 weeks ago
Director, Total Rewards & Payroll (REQ921)
$108K - $130K *
Champion the execution of a comprehensive compensation strategy across a multi-site organization, ensuring alignment with business goals and operational efficiency while overseeing payroll accuracy an...
3 weeks ago
Director, Total Rewards & Payroll (REQ921)
$110K - $130K *
Lead the charge in operationalizing a comprehensive compensation philosophy across a multi-site organization, ensuring effective execution of annual cycles, internal equity, and payroll oversight whil...
3 weeks ago
$134K - $157K *
Empower a creative team to bring innovative design concepts to life while mentoring junior talent and collaborating with clients. Lead presentations and manage multiple projects, ensuring strategic in...
2 weeks ago
Director / Senior Director, Quality
$200K - $270K *
Lead the development and execution of GxP quality systems, ensuring compliance and oversight for clinical and CMC quality. Drive vendor qualification, audits, and training while fostering a culture of...
3 weeks ago
Director, Partner Marketing (Remote)
$125K - $150K *
Lead and innovate partner marketing strategies across diverse retail segments, managing a team to drive growth and enhance relationships. Collaborate cross-functionally to develop impactful campaigns...
4 weeks ago
Senior Design Manager - Business Banking & Investments
$228K - $285K *
Transform the design landscape by leading a talented team to elevate visual and interaction quality in financial software. Drive innovation, simplify complex workflows, and inspire designers to delive...
Reposted today
$93K - $166K *
Drive transformation initiatives by leading complex projects, collaborating with stakeholders, and implementing strategic recommendations to enhance operational excellence and achieve impactful result...
Yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.