Explore High-Paying Jobs in Missouri

Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.

Career Opportunities Across Missouri

Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.

Find Roles That Match Your Goals

Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.

Build Your Career in the Show-Me State

From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.

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$109K - $173K *

Elevate your career by partnering with us to enhance financial forecasting and reporting processes. Leverage your analytical skills to improve business intelligence systems and drive key performance i...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Elevate project success by leading preconstruction activities, including estimating, scheduling, and planning. Collaborate with clients and teams to ensure alignment with project goals while managing...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K *

Join a dynamic team to oversee complex enterprise implementations, ensuring successful delivery across multiple departments. Leverage AI tools and project management expertise to enhance stakeholder e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$117K - $176K *

Drive the development and governance of enterprise processes, ensuring alignment across operations and technology. Lead initiatives that enhance operational excellence and foster adoption of standardi...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $148K *

Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Lead the charge in delivering a $3.2B capital program across multiple regions. Ensure projects are executed safely, on schedule, and within budget while collaborating with key stakeholders to advance...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Energy & Utilities

$87K - $108K *

Join a team that's shaping the future of aviation planning. Lead projects, collaborate on innovative solutions, and build client relationships while advancing your expertise in emerging technologies a...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$125K - $150K *

Join us to drive growth in enterprise accounts, owning the full sales cycle from prospecting to closing. Collaborate with a dynamic team to convert leads into revenue while leveraging market insights...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $144K *

Drive success by leading commissioning projects for critical facilities. Collaborate with diverse teams to ensure compliance, manage schedules, and execute testing of complex systems, all while mainta...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Technical Services

$146K - $170K *

Lead the charge in enhancing client relationships and driving growth across our North American laboratory network. Oversee Client Service teams, ensuring seamless service delivery and proactive accoun...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Shape the future of defense programs by managing technology initiatives, supporting federal acquisitions, and driving business development efforts. Collaborate with diverse teams to translate complex...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$80K - $95K *

Drive multi-year program management for District Civil Works, coordinating budgets, schedules, and technical advice to enhance project execution and stakeholder engagement while ensuring compliance wi...

3 days ago

  •   Less than 5 years exp.  •   Technical Services

$120K - $185K *

Transform the future of engineering design by leading diverse teams to deliver high-quality electrical engineering solutions. Drive project success through strategic oversight, mentoring, and adherenc...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$105K - $130K *

Drive global events strategy and execution, ensuring alignment with GTM priorities to generate measurable business outcomes across the customer lifecycle, from acquisition to retention...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$275K - $300K *

Champion product growth by defining activation metrics and driving member engagement across diverse health solutions. Lead a cross-functional team to enhance user retention and optimize product strate...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$185K - $225K *

Lead the charge in delivering complex, cross-functional programs that drive innovation in consumer energy products. Collaborate with diverse teams to establish frameworks, manage risks, and ensure suc...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Energy & Utilities

$172K - $216K *

Help us drive growth in the utilities sector by leading a high-performing sales team. You'll shape strategies, build relationships, and coach sellers to excel in complex, multi-year deals, ensuring al...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Consumer Technology

$100K - $179K *

Lead the charge in enhancing digital presence and customer engagement. Drive technical delivery for software upgrades while managing project teams, resolving issues, and ensuring cross-functional coor...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$135K - $165K *

Pioneer operational excellence in Design leadership, managing workflows, prioritizing projects, and developing talent. Collaborate cross-functionally to enhance Design integration in AI-driven product...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $140K *

Transform domestic relocation programs by leading governance, strategy, and stakeholder engagement. Leverage expertise to enhance employee experiences and align policies with business needs while driv...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $105K *

Collaborate with us to manage federal government contracts, ensuring compliance and effective execution throughout the contracting lifecycle. Support proposal development, contract administration, and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Staffing

$182K - $215K *

Transform executive engagement by building strategic advisor relationships, designing impactful experiences, and leveraging industry insights to elevate pay governance as a strategic priority for clie...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$125K - $150K *

Transform strategic initiatives by leading partnerships that drive growth and innovation. Collaborate across teams to enhance business objectives and foster relationships that unlock new opportunities...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Legal & Accounting

$100K - $120K *

Elevate product innovation in the insurance sector by collaborating with cross-functional teams to develop and launch new offerings, enhance existing products, and drive market growth while ensuring c...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of high-paying jobs can I find in Missouri?question toggle

    Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.

  • Do Missouri jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.

  • Where in Missouri can I search for jobs?question toggle

    Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.

  • How can I find a Missouri job that fits my experience?question toggle

    Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.