Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
SAP Order to Cash Consultant, Director
$155K - $410K *
Drive impactful SAP Order to Cash initiatives, guiding client strategies and enhancing operational efficiency while mentoring teams and shaping business growth through innovative solutions and executi...
1 week ago
SAP Order to Cash Consultant, Director
$155K - $410K *
Drive client success by leading SAP Order to Cash initiatives, enhancing operational efficiency, and mentoring teams. Shape strategies, oversee engagements, and translate business needs into effective...
1 week ago
Director, Software Engineering - Platform Development
$150K - $180K *
Join a dynamic team to lead the development of innovative Microsoft-based platforms, driving modernization and AI integration while ensuring robust, scalable, and secure solutions in a highly regulate...
2 weeks ago
Director, AI Product Mgr - Low Code
$150K - $180K *
Transform business workflows by leading the development of low-code AI products that enhance efficiency and deliver measurable outcomes. Collaborate with teams to identify needs, validate solutions, a...
3 days ago
$140K - $180K *
Elevate customer insights by translating data into actionable product capabilities. Collaborate with cross-functional teams to prioritize initiatives, enhance marketing performance, and leverage AI fo...
1 week ago
Senior Preconstruction Manager
$110K - $130K *
Champion preconstruction initiatives for large-scale commercial projects, ensuring accurate estimates, client satisfaction, and alignment with company goals through effective communication and relatio...
Reposted 3 weeks ago
Senior Preconstruction Manager
$100K - $120K *
Shape the future of commercial construction by driving preconstruction excellence, managing budgets, schedules, and subcontractor relationships while ensuring client satisfaction and project alignment...
Reposted 3 weeks ago
Director - Portfolio Valuation & Decision Analysis
$112K - $236K *
Drive strategic decision-making by evaluating investment alternatives and lifecycle opportunities. Collaborate with cross-functional teams to optimize portfolio value and support program planning thro...
2 weeks ago
$175K - $210K *
Lead the charge in AI-driven product innovation, enhancing workflows and productivity while establishing governance for safe, scalable solutions. Collaborate across teams to unlock revenue opportuniti...
Yesterday
$110K - $130K *
Empower teams by translating complex data into actionable insights, guiding strategic financial modeling, and enhancing decision-making processes for portfolio companies through collaborative relation...
2 days ago
Principal Architect - Data Centers
$125K - $200K *
Join a team that's redefining architectural excellence by leading global projects, driving business growth, and fostering client relationships while overseeing studio operations and strategic initiati...
5 days ago
$80K - $95K *
Drive design excellence by leading a talented team, overseeing operations, and ensuring compliance with industry standards while fostering professional growth and collaboration across multiple locatio...
3 days ago
Principal Product Manager, Agentic AI
$280K - $300K *
Pioneer innovative AI solutions in workforce management, leading product development from concept to deployment. Collaborate with engineers and executives to create impactful agentic products that enh...
3 weeks ago
$125K - $150K *
Champion a robust security program, leading a team to achieve SOC 2 Type 2 attestation while ensuring secure engineering practices across diverse products and cloud environments. Drive compliance, ris...
3 weeks ago
Associate Director of IT - Enterprise Apps/Data
$120K - $145K *
Transform your career by leading enterprise applications and data strategies. Drive innovation, optimize processes, and ensure security across Oracle Fusion Cloud systems while collaborating with cros...
1 week ago
Managing Director Global Delivery (Hub)
$125K - $295K *
Lead the charge in optimizing global delivery operations, ensuring seamless hub economics and resource allocation. Collaborate with finance and commercial teams to drive data-driven decisions and main...
Reposted 3 days ago
IT Business Relationship Director, Americas
$132K *
Lead the charge in bridging IT and program operations across the Americas, ensuring service delivery aligns with business needs. Build trust with leadership, manage escalations, and enhance communicat...
3 days ago
Implementation Manager, Financial Services
$100K - $120K *
Accelerate client success by owning the onboarding and rollout for enterprise clients, ensuring smooth transitions from purchase to sustained usage. Collaborate with cross-functional teams to drive ad...
1 week ago
Director, Trust Management CAO
$160K - $200K *
Lead the charge in transforming trust administration through strategic oversight, ensuring compliance and operational excellence while enhancing client experiences and fostering cross-functional colla...
3 weeks ago
Director, Assurance Risk Management
$200K - $250K *
Shape the future of risk management by leading compliance and quality initiatives. Drive effective implementation of technology solutions while providing operational leadership across key programs and...
Yesterday
$110K - $130K *
Transform organizational change by leading client engagements, developing tailored OCM plans, and ensuring user adoption with minimal disruption. Collaborate with stakeholders to drive successful chan...
1 week ago
Senior Product Manager, Data Products
$130K - $155K *
Elevate data product experiences by defining metrics that drive value for Mural. Collaborate across teams to shape insights, enhance reporting, and ensure data integrity, empowering organizations to m...
2 weeks ago
$80K - $95K *
Join a team that's dedicated to enhancing client experiences through exceptional facility management. Oversee multiple locations, collaborate on strategic initiatives, and ensure a welcoming atmospher...
1 week ago
Senior Director, Agent Success
$150K - $180K *
Transform the agent experience by leading strategy across recruitment, onboarding, and ongoing support. Drive engagement and success through cohesive learning and development initiatives, ensuring age...
4 days ago
Senior Director, Product Finance
$227K - $280K *
Lead strategic finance initiatives to empower product decisions, driving financial evaluations and business cases for new product lines. Collaborate with C-suite and product teams to optimize resource...
3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.