Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$110K - $130K *
Unlock potential by leading complex technology projects and programs, ensuring successful delivery through disciplined management practices, AI-enabled methods, and strong client relationships. Drive...
Yesterday
$110K - $130K *
Shape the future of technology delivery by leading complex projects and programs. Collaborate with cross-functional teams to drive client outcomes, leveraging AI-enabled methods and fostering strategi...
Yesterday
Product Manager, Clinical Programs & Case Management
$86K - $138K *
Unlock innovative healthcare solutions by leading product strategy and lifecycle management for clinical programs. Collaborate across teams to enhance member experiences and drive business value while...
2 weeks ago
$99K - $232K *
Transform your career by leading Oracle implementation projects, managing teams, and ensuring quality delivery. Oversee complex workstreams, coach junior staff, and drive client-focused solutions in a...
Today
$110K - $130K *
Inspire and elevate design excellence as you lead a talented team, setting and maintaining visual standards, driving innovative campaigns, and partnering cross-functionally to advance Dandy's brand an...
Reposted 2 weeks ago
Managing Director - Market Development & Revenue Growth (Insurance Growth Platforms)
$180K - $220K *
Lead the charge in driving growth across insurance platforms by building strategic alliances, developing executive relationships, and executing market strategies to enhance revenue and expand opportun...
2 weeks ago
$125K - $150K *
Lead the design and governance of compensation strategies, ensuring market competitiveness and compliance. Oversee a team to deliver innovative solutions that align with business objectives and enhanc...
3 days ago
Field Operations Director - AMER
$120K - $150K *
Partner with us to build a scalable sales operations framework across the Americas, enhancing forecast accuracy and pipeline management while fostering strong relationships with field leadership and d...
3 weeks ago
Director of Business Operations
$125K - $150K *
Transform business operations by leading systems and technology initiatives that enhance efficiency, drive AI enablement, and streamline processes across the organization, ensuring a robust foundation...
3 weeks ago
Professional Services, Program Manager
$110K - $130K *
Advance your career by leading complex, multi-workstream programs that drive customer transformation and deliver meaningful business value through effective project management and collaboration with d...
Today
$125K - $159K *
Innovate connections between business units and IT, translating goals into actionable tech roadmaps. Manage projects from ideation to execution by fostering collaboration and driving accountability ac...
Reposted today
$95K - $115K *
Manage complex modular construction projects from award to delivery, integrating design, VDC/BIM, and financial performance. Lead teams and engage clients to ensure cohesive execution and successful p...
1 week ago
$125K - $150K *
Join a team that's defining strategies to win new business and drive growth. Lead capture development, engage stakeholders, and create compelling proposals to enhance competitive positioning and secur...
Reposted 3 days ago
$90K - $130K *
Drive exceptional client experiences by leading client services strategy and operations across screening services. Empower teams to deliver timely, accurate support while fostering a culture of accoun...
1 week ago
$150K - $180K *
Lead the charge in optimizing our national Revenue Cycle Management sales team, driving performance and market expansion. Collaborate cross-functionally to enhance client relationships and ensure cons...
Yesterday
$174K - $215K *
Architect the future of vulnerability intelligence by owning product strategy, roadmap, and AI integration. Collaborate with engineering and analysts to deliver impactful solutions that enhance custom...
4 days ago
Sr Manager, Empaveli Publications - US Medical Affairs
$125K - $150K *
Shape the future of scientific communications by leading global publication strategies in nephrology and hematology. Collaborate with cross-functional teams to ensure timely, high-quality deliverables...
4 days ago
Manager, Procurement Compliance, Governance and Data & Analytics
$110K - $172K *
Shape global procurement governance and compliance by leading analytics, training, and process excellence initiatives. Drive transformation and data management in a collaborative environment to enhanc...
2 weeks ago
Digital Consulting Manager, Oracle Cloud SCM & P2P
$145K - $170K *
Drive transformative Oracle Cloud P2P solutions for Higher Education, guiding teams and clients through strategic implementations while fostering a collaborative culture and mentoring junior staff to...
2 weeks ago
Director, Value Stream Transformation
$164K - $225K *
Champion enterprise transformation by leading cross-functional initiatives, ensuring governance and execution quality across value-streams. Collaborate with leaders to drive measurable outcomes and bu...
2 weeks ago
Director of Revenue Enablement
$150K - $180K *
Champion a transformative revenue enablement initiative, leveraging AI to enhance sales effectiveness and streamline coaching. Lead a team to integrate innovative tools and data-driven insights across...
Reposted today
$96K - $133K *
Join a team that's dedicated to delivering high-quality projects on time and within budget. As a key player, you'll coordinate efforts across departments, ensuring effective communication and resource...
2 weeks ago
$88K - $105K *
Lead the charge in project management by directing construction efforts, ensuring client satisfaction, and overseeing project profitability while coordinating with various stakeholders to achieve stra...
Yesterday
Project Controls Manager and CPM Scheduler - Lake City Microgrid and CHP
$100K - $120K *
Transform project execution by developing and maintaining comprehensive CPM schedules, integrating multiple stakeholders, and ensuring timely updates to drive successful outcomes in large-scale indust...
2 weeks ago
Senior Manager, Facility Management (Americas)
$123K - $164K *
Shape the future of facility management by leading a $59M portfolio across North America and LATAM. Collaborate with cross-functional teams to ensure compliance, optimize budgets, and enhance service...
Reposted yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.