Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$218K - $256K *
Lead the charge in shaping IT strategy and operations for a remote-first SaaS company. Drive service delivery, enhance employee technology experiences, and build a high-performing IT organization whil...
3 weeks ago
$180K - $248K *
Advance our product strategy by leading the integration of data center operations into Prism, enhancing diagnostics and decision-making for operators and executives alike. Collaborate with cross-funct...
Reposted 4 days ago
Director, Powered Land Development
$150K - $180K *
Empower the powered land development function by sourcing, evaluating, and advancing sites for solar and storage projects. Lead negotiations, engage stakeholders, and build financial models to transfo...
4 weeks ago
$260K *
Join a team that's driving digital transformation by managing client accounts, developing strategies, and delivering innovative technology solutions. Build long-term relationships while collaborating...
3 weeks ago
$160K - $200K *
Elevate client marketing strategies by leading transformative engagements using Adobe's ecosystem. Collaborate with senior executives to design data-driven solutions that enhance customer experiences...
3 weeks ago
$110K - $130K *
Join a dynamic team to lead proposal and security response efforts, driving innovation and quality. Manage a skilled group, streamline processes, and enhance collaboration across functions to achieve...
Reposted 2 days ago
Associate Director - Cost Manager / Quantity Surveyor - Data Center Construction
$110K - $130K *
Drive high-value cost management services for a large-scale data center program, ensuring effective client communication and leadership across multiple workstreams while enhancing cost management proc...
2 days ago
Change Management Lead - R&D Advisory
$100K - $120K *
Help us drive change management initiatives in life sciences R&D, enhancing efficiency and effectiveness across research, clinical, and regulatory operations while leading stakeholder engagement and a...
3 weeks ago
$110K - $145K *
Join a team that's shaping the future of cloud infrastructure by leading engineering efforts for a cutting-edge Operational Decisioning Platform. Drive innovation, enhance developer experience, and en...
3 weeks ago
$80K - $100K *
Join a team that's driving impactful client strategies in digital marketing. As a Supervisor, you'll lead a dynamic team, manage client relationships, and oversee integrated campaigns across omnichann...
3 days ago
Application Portfolio Owner - Finance and Accounting
$108K - $130K *
Empower your career by managing the Finance and Accounting application portfolio, ensuring alignment with business strategy while optimizing costs, performance, and risk. Collaborate with stakeholders...
2 weeks ago
Product Manager - Vendor Oversight
$113K - $197K *
Lead the charge in defining product strategy and roadmap, translating business objectives into actionable plans. Collaborate with cross-functional teams to ensure successful implementation and operati...
3 weeks ago
Director, Business Systems & Solution Architecture (D365 F&O)
$155K - $170K *
Lead the charge in shaping enterprise business solutions through hands-on architecture and delivery in Microsoft Dynamics 365 Finance & Operations, focusing on integration, process optimization, and o...
Reposted 3 days ago
Sr. Change Management Manager (Remote - EST)
$130K - $150K *
Lead change management initiatives by strategizing and implementing processes that support organizational transformation. Collaborate with teams to minimize risks and enhance project outcomes across d...
1 week ago
$88K - $147K *
Lead the charge in operational excellence by managing a dynamic Facility Services team, enhancing customer experience, and driving business growth through effective service delivery and continuous imp...
2 weeks ago
Manager, Integrated Technology
$146K - $271K *
Empower a high-performing team to deliver innovative risk solutions, driving sales strategy and enhancing customer experience through effective leadership and collaboration across functions. Shape the...
Today
Technical Director, Aviation Sector
$200K - $383K *
Engage in shaping the future of aviation modernization by leading technical strategies and integration efforts. Collaborate with key stakeholders to enhance air traffic management and safety-critical...
2 days ago
Senior Director - Payroll and HR Services
$179K - $190K *
Shape the future of payroll and HR services by leading strategic initiatives, optimizing operations, and ensuring compliance across the employee lifecycle. Drive excellence in service delivery while f...
4 days ago
Program Director, Professional Services
$150K - $170K *
Lead a dedicated team to drive client success across diverse delivery modes, ensuring effective governance and coordination. Drive business development within a portfolio, nurturing critical client re...
Reposted 3 weeks ago
Staff Technical Program Manager, Enterprise Transformation
$120K - $145K *
Shape complex, cross-functional programs that drive enterprise transformation, focusing on Customer Data Platform implementation and AI initiatives. Collaborate with diverse teams to ensure strategic...
2 weeks ago
Senior Director, Client Partner
$152K - $203K *
Elevate client partnerships by uncovering growth opportunities and building trusted executive relationships. Drive strategic conversations that connect client needs to innovative solutions, fostering...
4 days ago
Director, Environmental Services (US)
$125K - $150K *
Champion the growth of a U.S. Environmental Services Division by leading market strategies, client relationships, and project delivery while building a high-performing team to enhance technical capabi...
1 week ago
Senior Manager, Revenue Operations
$190K - $250K *
Launch a transformative Revenue Operations function to drive growth, partnering with leadership to design analytics, forecasting, and operational strategies that enhance performance across sales, mark...
Reposted 3 days ago
Senior Estimating Manager, Solar & BESS
$108K - $130K *
Transform preconstruction efforts by leading cross-functional teams, managing complex project pursuits, and collaborating with senior leadership to deliver competitive proposals and accurate estimates...
1 week ago
Design Manager - Transit Design Build
$274K - $438K *
Pioneer innovative transit solutions by leading design teams on mega projects. Drive client relationships, manage project performance, and ensure quality delivery on time and budget while mentoring st...
Reposted yesterday
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.