Find your next career opportunity with Missouri jobs paying $100,000 or more on Ladders. Browse vetted professional roles across the state, from major employers in Kansas City and St. Louis to growing organizations in Springfield, Columbia, and other communities. Listings may include opportunities in technology, healthcare, finance, engineering, operations, and executive leadership.
Missouri’s diverse economy supports professional careers across industries such as financial services, healthcare, manufacturing, logistics, technology, and agriculture. Whether you’re looking for an established corporate role or a position with a growing organization, explore openings that match your experience, skills, and compensation goals.
Use Ladders to discover vetted jobs with salaries of at least $100,000. Review each listing for details about responsibilities, qualifications, location, and compensation, then focus your search on opportunities that align with your career plans. Job availability and salary details vary by employer and role.
From metropolitan career hubs to communities throughout Missouri, high-paying roles can offer different work environments and paths for advancement. Explore current listings and find professional opportunities that fit the way you want to work and grow.
$135K - $150K *
Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...
2 weeks ago
Sr IT Project & Infrastructure Lead
$125K - $150K *
Join a team that's driving IT excellence by leading operations, enhancing security, and spearheading compliance initiatives. Collaborate with global teams to implement scalable solutions and support a...
2 weeks ago
$100K - $120K *
Join a team that's dedicated to empowering your career as you manage project costs, analyze bids, and foster strong client relationships. Collaborate with diverse experts while driving strategic initi...
Today
Director, Customer Success Onboarding
$120K - $145K *
Lead the onboarding function for diverse customer segments, managing a team to ensure a seamless transition from contract to go-live. Collaborate cross-functionally to enhance processes and drive cust...
3 weeks ago
$80K - $95K *
Manage integrated master schedules and coordinate cross-functional teams to ensure project alignment and timely deliverables. Proactively assess risks, facilitate client communications, and contribute...
1 week ago
Lead Product Manager (Intellectual Property)
$125K - $150K *
Drive innovative product strategies and outcomes for a major AI platform, collaborating across teams and advocating for customer needs to enhance intellectual property workflows and product performanc...
Reposted 4 weeks ago
Lead Product Manager (Intellectual Property)
$120K - $145K *
Drive your career forward by leading product strategy for a unified AI platform, delivering innovative solutions, and collaborating with cross-functional teams to enhance customer experiences and achi...
Reposted 4 weeks ago
Project Manager- Construction Technologies
$84K - $111K *
Elevate project success by managing diverse construction projects from start to finish. Ensure quality, maintain schedules, and engage with clients, contractors, and teams while adapting to evolving p...
Reposted 4 weeks ago
$170K - $200K *
Unlock potential by leading strategic finance initiatives, enhancing planning, forecasting, and reporting processes. Collaborate with executives to drive operational excellence and scale the finance f...
4 days ago
Project Manager - Federal Programs (TS/SCI)
$84K - $142K *
Lead the charge in delivering geospatial solutions for federal clients. Manage project scope, schedule, and budget while collaborating with cross-functional teams to translate complex requirements int...
Reposted 3 days ago
Engineering Manager, Messaging & Applications Teams
$120K - $145K *
Lead and develop dynamic engineering teams to enhance communication systems that improve health equity outcomes for underserved patients. Drive technical direction, manage shared codebases, and collab...
Reposted 3 days ago
Commissioning Project Engineer
$120K - $150K *
Develop and manage commissioning processes across projects, ensuring effective collaboration with diverse stakeholders. Bring expertise in mechanical, electrical, and plumbing systems to deliver excep...
Reposted 2 days ago
$138K - $198K *
Innovate financial strategies as a key partner in FP&A, driving insights and accountability across R&D and G&A. Own financial models, forecasts, and planning processes to support strategic decision-ma...
4 weeks ago
$140K - $175K *
Drive operational excellence by leading strategic initiatives and managing a team to enhance Care Operations. Transform high-level strategies into scalable systems that improve care delivery and patie...
4 weeks ago
Senior Director, Product Management (Infra)
$245K - $279K *
Architect innovative product strategies that enhance customer experiences and drive business growth. Lead cross-functional teams to solve complex challenges while leveraging technology for sustainable...
3 weeks ago
(USA) Senior Manager, Realty Project Management - DS
$80K - $155K *
Drive the execution of multiple realty projects by managing timelines, budgets, and vendor relationships. Collaborate with cross-functional teams to ensure efficient delivery while aligning initiative...
2 weeks ago
Director, Utilization Management Operations
$182K - $247K *
Join a team that's redefining operational excellence in healthcare. Lead a diverse team to streamline utilization management processes, enhance technology integration, and drive measurable improvement...
1 week ago
Director, BI & Data Engineering
$165K - $195K *
Lead the charge in developing and managing a robust Enterprise Data Warehouse on Databricks. Drive BI solutions, mentor a team, and ensure data quality while collaborating across departments to enhanc...
1 week ago
$150K - $180K *
Join a team that's redefining renewable energy asset management. Lead the oversight of a diverse portfolio, ensuring optimal performance, compliance, and financial returns while managing third-party o...
4 weeks ago
Director, Strategic PartnershipsStrategic Partnerships & Business Development
$125K - $150K *
Join a team that's driving strategic partnerships in Retail and Hospitality. Manage relationships with technology providers, identify growth opportunities, and develop compelling business cases to enh...
3 weeks ago
International Program Management Support - Mid
$125K - $150K *
Accelerate progress at the forefront of project management by leading complex programs, performing programmatic analysis, facilitating funding coordination, and ensuring execution excellence in collab...
Reposted 2 weeks ago
$84K - $105K *
Drive project success by managing client relationships and leading implementation strategies. Collaborate with teams to assess needs, develop plans, and ensure timely delivery while navigating challen...
2 weeks ago
$84K - $105K *
Deliver exceptional client engagement by managing project success, assessing needs, and developing strategic plans. Lead cross-functional teams to ensure timely and budget-compliant implementations wh...
3 weeks ago
$100K - $120K *
Unlock growth as a key leader driving land development projects, managing design, permitting, and client relations while collaborating with industry experts to deliver innovative solutions through div...
Reposted 3 weeks ago
$100K - $120K *
Innovate in a dynamic role leading design and client management efforts on diverse land development projects. Collaborate with industry leaders to enhance growth and drive impactful solutions across v...
Reposted 3 weeks ago
What types of high-paying jobs can I find in Missouri?
Missouri listings may include professional roles in technology, healthcare, finance, engineering, manufacturing, logistics, operations, and executive leadership. Available positions depend on current employer hiring needs.
Do Missouri jobs on Ladders pay at least $100,000?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review the individual listing for its compensation information and requirements.
Where in Missouri can I search for jobs?
Explore opportunities in cities such as Kansas City, St. Louis, Springfield, and Columbia, as well as other locations across Missouri. Availability varies by role and employer.
How can I find a Missouri job that fits my experience?
Browse current listings and compare responsibilities, qualifications, location, and compensation with your experience and career goals. Apply to positions that align with your background.