Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$100K - $176K *

Shape the future of AI-driven products by leading the development and market launch of innovative solutions. Collaborate with teams to enhance customer experiences and drive product success through st...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Energy & Utilities

$150K - $180K *

Elevate sales performance by developing and scaling a forward-thinking sales enablement strategy. Lead onboarding, ongoing skills enhancement, and sales methodology adherence while leveraging AI-drive...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$100K - $120K *

Elevate your career by designing and optimizing EpicCare Ambulatory workflows. Collaborate with clinicians to enhance EHR functionality, troubleshoot issues, and ensure seamless operations across heal...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$194K - $285K *

Innovate in the credit space by leading a dynamic underwriting team. Drive strategy, mentor talent, and establish best-in-class credit programs while collaborating with internal and external partners...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$140K - $175K *

Empower Apollo's frontier partnerships by deepening collaborations with AI-native platforms and foundation model companies. Analyze the evolving landscape and drive monetization strategies while build...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$79K - $94K *

Lead the development and execution of training programs while optimizing workflows to enhance provider experiences. Collaborate with stakeholders to ensure effective training delivery and continuous i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$84K - $124K *

Join us to lead the acquisition and management of right of way agreements for fiber optic projects across North America, collaborating with stakeholders to ensure compliance and successful negotiation...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $200K *

Drive global mechanical category strategy for advanced thermal management systems, ensuring optimal cost, quality, and reliability across a diverse supplier ecosystem while supporting scalable data ce...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$198K - $258K *

Lead the charge in defining and governing architectural strategies for a secure and scalable software ecosystem across device and digital platforms, influencing cross-functional teams and senior stake...

United StatesRemote

Reposted 6 days ago

  •   11 - 15 years exp.  •   Healthcare

$155K - $197K *

Innovate as a Tech Lead, driving architectural evolution and engineering execution for a global web platform. Collaborate with cross-functional teams to enhance digital experiences through advanced AI...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $205K *

Join a team that's transforming payroll solutions by leading Workday Payroll implementations, optimizing processes, and mentoring junior consultants to enhance client efficiency and satisfaction...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Take ownership of a 24x7 Security Operations Center, leading a team of SOC analysts. Drive performance, manage client relationships, and ensure high-quality investigations while fostering team develop...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$104K - $176K *

Champion the Lead-to-Opportunity domain by driving product strategy, mentoring analysts, and enhancing the GTM tech stack. Influence the roadmap and ensure seamless lead conversion while collaborating...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Lead product marketing initiatives by crafting compelling messaging and strategies that drive customer engagement and adoption. Collaborate cross-functionally to ensure alignment and measure performan...

United StatesRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$116K - $193K *

Lead the charge in defining and executing the product strategy for AI and analytics, driving innovation across pharmacy management platforms. Collaborate with cross-functional teams to deliver scalabl...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$180K - $220K *

Drive the development of innovative security systems using AI/ML, managing risk across identity and access management. Collaborate with cross-functional teams to enhance security while maintaining ope...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$103K - $176K *

Transform downstream marketing for cutting-edge medical devices. Drive product launches, develop compelling content, analyze market trends, and ensure regulatory compliance across global regions while...

RemoteRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Transform global benefits strategy by leading cross-functional teams and advising executives on integrated portfolio management, compliance, and financial sustainability to enhance employee experience...

United StatesRemote

1 month ago

  •   11 - 15 years exp.  •   Information Technology

$100K - $120K *

Join a team that's focused on enhancing client delivery and relationship growth. Drive data-driven strategies and cross-functional collaboration to optimize post-sale operations, ensuring exceptional...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K - $190K *

Innovate the deployment process by leading two squads to ensure seamless integration and self-service capabilities for customers, driving measurable outcomes and enhancing product effectiveness in a d...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Elevate your career by joining a dynamic team focused on transforming corporate learning. As a senior leader, you'll drive strategic initiatives, engage with top executives, and shape the future of wo...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $140K *

Drive the development of predictive analytics models to enhance digital assessment operations, collaborating across teams to optimize decision-making and reduce costs while supporting strategic goals...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$108K - $130K *

Champion the development of Planning and Inventory strategies, leading a team to optimize supply chain performance and ensure compliance. Drive process improvements and manage supplier relationships t...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$118K - $178K *

Shape strategic initiatives by leading key deliverables and financial analyses. Collaborate with partners to enhance business processes and drive impactful recommendations, ensuring alignment and time...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.