Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$164K - $205K *

Elevate scientific rigor in real-world evidence development. Collaborate with cross-functional teams to ensure agent conceptualization and evaluation meet scientific standards, driving impactful solut...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Grow your career by driving sales and developing strategic relationships within major sectors across the AMER region, ensuring revenue maximization and effective execution of account strategies...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$140K - $170K *

Champion the future of customer engagement by leading lifecycle marketing strategies. Drive retention and loyalty through data-driven personalization across multiple channels, maximizing customer life...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $115K *

Advance the payroll function for a diverse workforce, ensuring compliance and accuracy across multiple states. This hands-on role requires expertise in payroll systems and regulations, driving process...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Hospitality & Recreation

$110K - $145K *

Champion innovative solutions as a Senior Business Analyst, driving requirements gathering and Agile processes to enhance custom applications for DHS. Collaborate with teams to streamline operations a...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$222K - $288K *

Advance your career by leading global infrastructure strategy and operations. Drive modernization across cloud, networking, and security while ensuring compliance and scalability for 24/7 clinical and...

United StatesRemote

Reposted 2 days ago

  •   11 - 15 years exp.  •   Healthcare

$125K - $150K *

Shape high-impact growth in retail partnerships by overseeing field operations, driving application volume, and enhancing point-of-sale conversion rates. Collaborate with teams to optimize strategies...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$100K - $140K *

Lead the charge in designing and executing rail projects, ensuring compliance and quality. Collaborate with multidisciplinary teams and strengthen client relationships while managing project delivery...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Partner with us to tackle complex operational challenges, driving impactful initiatives across our portfolio. This role offers hands-on experience and growth opportunities, ideal for future leaders ea...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $105K *

Partner with us to provide exceptional administrative support to a VP, managing complex calendars, travel logistics, and cross-functional relationships while ensuring smooth operations and effective c...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $180K *

Drive operational excellence by managing the leadership team's cadence, metrics, and contract operations. This hands-on role blends business judgment with execution, ensuring alignment and efficiency...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$176K - $236K *

Lead the charge in global regulatory project management, driving oncology strategies and submissions across regions. Collaborate with cross-functional teams to ensure compliance and timely market acce...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion strategic HR initiatives that drive organizational design, talent development, and change management. Collaborate with senior leaders to enhance employee experience and align workforce planni...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$137K - $202K *

Shape the future of compensation products by owning the development and management of a comprehensive range-setting tool and analytics roadmap that enhances productivity for Compensation Partners and...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$185K - $205K *

Shape the future of customer success by leading complex SaaS solutions, driving strategic partnerships, and mentoring teams to enhance value delivery and accelerate growth across enterprise accounts...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Join a team that's redefining payment solutions! Drive strategic product management, leading innovative card offerings and fostering high-performing teams while shaping market-leading strategies and e...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$149K - $173K *

Lead quality and food safety initiatives across North America, ensuring compliance and audit readiness. Drive continuous improvement and operational excellence through technical expertise and collabor...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Food & Beverages

$110K - $130K *

Explore a pivotal role overseeing financial management, budgeting, and compliance. Collaborate with leadership to provide insights that drive operational decisions and ensure organizational sustainabi...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Media

$105K - $115K *

Engage with us to lead multiple client implementations, ensuring seamless transitions and high satisfaction. Collaborate cross-functionally, manage project timelines, and mentor team members while dri...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform digital growth strategies by overseeing website, SEO, and campaigns. Drive content distribution, partner marketing, and harness AI for analytics, ensuring effective buyer engagement and meas...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$95K - $115K *

Champion product marketing by driving launches, pricing strategies, and sales enablement for key therapy lines. Collaborate cross-functionally to ensure compliance and optimize performance metrics, pa...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Transform strategic initiatives by coordinating and executing projects that enhance organizational effectiveness, support leadership communication, and drive process excellence across departments, ens...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$105K - $125K *

Engage in a dynamic product role, driving AI-assisted development from concept to delivery. Collaborate with cross-functional teams to enhance workforce analytics, ensuring customer needs shape produc...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$228K - $342K *

Empower your career by leading strategic project management initiatives across early drug development. Drive process optimization, cultivate high-performing teams, and collaborate with executives to a...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's dedicated to delivering exceptional client service and operational excellence. As a Program Manager, you'll oversee program execution, account management, and financial oversight wh...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.