Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$110K - $172K *

Unlock potential by leading the design and deployment of a global Quality Management System, ensuring compliance and operational excellence across multiple aerospace sites while fostering collaboratio...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Pioneer operational excellence by driving staffing visibility and standardized planning across diverse content teams. Collaborate with stakeholders to enhance resource management and optimize project...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

$201K - $251K *

Champion Quality governance by leading the development and management of Quality Agreements across global operations, ensuring compliance and effective partnerships with internal and external stakehol...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Transform the contracting process by managing the lifecycle of agreements, ensuring efficient execution while balancing risk and compliance. Collaborate with cross-functional teams to support business...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Drive operational excellence by leading the S&OP strategy, aligning resources with business goals, and optimizing capacity planning across the network to enhance efficiency and service delivery...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$245K - $286K *

Elevate clinical quality assurance through strategic leadership and oversight of global trials, ensuring compliance with GCP regulations. Drive quality culture and inspection readiness while mentoring...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Lead transformative Workday implementations, managing client relationships and project lifecycles. Drive innovation and strategic growth while ensuring exceptional customer satisfaction and effective...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $160K *

Engineer innovative cloud-native solutions by leading architecture design and implementation. Collaborate with cross-functional teams to drive technical strategies while mentoring talent, ensuring pro...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$162K - $202K *

Oversee end-to-end technology program delivery for credit and lending products, collaborating across multiple teams to ensure compliance and operational readiness while driving strategy and managing r...

RemoteRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$140K - $187K *

Lead the charge in strategic and operational excellence for substation engineering, overseeing project execution, team development, and client relationships to drive growth and ensure high-quality del...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$160K - $200K *

Champion revenue growth by leading proposal operations and capture strategies. Drive compliance and execution across multiple concurrent pursuits while building scalable infrastructure to enhance mark...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Business Services

$125K - $150K *

Transform product strategy by leading impactful initiatives that enhance user experience and drive growth. Collaborate with cross-functional teams to deliver innovative solutions that delight customer...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$172K - $238K *

Shape compliance strategies by operationalizing key frameworks, guiding stakeholders, and ensuring adherence to regulations. Collaborate across teams to enhance risk management and support product com...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$172K - $232K *

Lead the GCP Inspection Management team to ensure inspection readiness and compliance. Oversee strategy development, cross-functional collaboration, and risk mitigation for successful regulatory inspe...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead and develop a high-performing team of enterprise account executives, driving revenue growth and shaping sales strategies in the finance sector. Engage with senior decision-makers and manage compl...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$280K - $330K *

Empower a dynamic engineering team by leading technical architecture, enhancing system reliability, and driving scalable solutions that support rapid growth in a fast-paced fintech environment. Foster...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Lead the charge in executing population health strategies, ensuring high-quality consulting delivery and team performance across regions. Collaborate with leadership to drive impactful solutions and f...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$108K - $162K *

Champion customer support by managing maintenance services and operations. Lead a team to ensure timely resolutions and enhance product performance while utilizing technical expertise and strategic pl...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$176K - $293K *

Develop and implement strategic account plans to drive sales growth and build relationships with key decision-makers in healthcare. Collaborate with cross-functional teams to achieve business goals an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$192K - $229K *

Lead the charge in delivering comprehensive data migration services for SAP-enabled transformations, ensuring effective governance, client engagement, and execution of best practices across diverse da...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock potential by leading large-scale power generation projects, managing site relationships, and ensuring seamless execution from construction to commissioning. Collaborate with diverse teams to de...

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform complex cybersecurity narratives into engaging content that captivates audiences across various formats. Collaborate with cross-functional teams to enhance brand storytelling and drive conve...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$140K - $175K *

Join a dynamic team to drive the strategy and roadmap for Sales and Marketing platforms, focusing on Salesforce and marketing automation. Collaborate with stakeholders to prioritize initiatives and de...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $251K *

Pioneer innovative technology strategies and architectural solutions across Agile teams, driving AI-enabled engineering transformation and ensuring scalable, secure, and maintainable solutions for ent...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$238K - $357K *

Transform growth strategies by leading AI initiatives, targeting key customers, and driving adoption through innovative partnerships and market insights. Collaborate across teams to enhance product of...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.