Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$120K - $145K *

Transform the future of tax compliance by building a scalable filing platform and remittance infrastructure, enabling seamless global transactions and automation for international sellers. Drive innov...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$190K - $275K *

Advance the Data & Distribution Partnerships function by innovating and scaling data reseller and distribution models, building commercial arrangements, and leading a team to create revenue-generating...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful program management by leading cross-functional initiatives, ensuring alignment with strategic goals, and delivering measurable results in a dynamic environment. Collaborate effectively...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$175K - $220K *

Join a team that's shaping infrastructure projects through expert scheduling leadership. Your strategic planning and risk management skills will optimize resource use and ensure timely delivery in a c...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$205K - $240K *

Shape the future of supply chain technology by leading engineering teams in optimizing platforms for logistics and order management. Drive innovation and efficiency while managing a diverse team of ex...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$120K - $145K *

Lead the charge in product strategy and execution for Driver and Rider applications, ensuring a seamless user experience across mobile and web platforms while collaborating closely with engineering an...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $147K *

Inspire and elevate employee engagement through strategic internal communications. Collaborate with leaders to craft and deliver impactful messaging that drives understanding of company goals and fost...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $140K *

Drive product innovation by leading the development of AI-enabled solutions for public sector agencies, enhancing early childhood systems through strategic vision, technical architecture, and customer...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K - $400K *

Elevate your career by managing the lifecycle of vendor agreements and contracts. Collaborate across departments to ensure compliance and streamline workflows, safeguarding business interests while mi...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Join a team that drives operational excellence in mission-critical environments. Lead strategic initiatives, manage resources, and ensure compliance with service level agreements while fostering innov...

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$114K - $143K *

Drive operational excellence as a Program Manager, enhancing EPD processes and collaboration. Leverage data insights to identify trends, improve efficiency, and support cross-functional teams in a dyn...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$170K - $222K *

Drive strategic transformation initiatives across Product, GTM, and Operations. Lead cross-functional teams, manage complex portfolios, and deliver measurable results while fostering clarity and accou...

RemoteRemote

4 days ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $160K *

Drive your career with a strategic role in Product Operations, partnering with leaders to transform complex challenges into actionable insights, while enhancing cross-functional collaboration and leve...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the technical implementation of Synapse products, ensuring high-quality solutions and customer satisfaction. Collaborate with project teams, manage infrastructure deployment, and integrate health...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Drive execution of complex technical initiatives, translating business vision into actionable programs. Collaborate with cross-functional teams to ensure alignment with company objectives and measurab...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$190K - $210K *

Advance our real estate strategy by leading portfolio planning, workplace design, and data analysis. Collaborate with internal teams and external partners to optimize office spaces, enhance employee e...

United StatesRemote

6 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$168K - $231K *

Drive transformation by partnering with cross-functional teams to design and implement effective product operations, ensuring alignment with strategic goals and enhancing organizational effectiveness...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join our dynamic Account Management Team to drive growth in the corporate occupier software market. Leverage your sales expertise to build lasting client relationships and uncover new opportunities wh...

RemoteRemote

6 days ago

  •   Less than 5 years exp.  •   Business Services

$120K - $145K *

Lead strategic product initiatives in advanced surgical technologies, driving development and commercialization efforts. Collaborate with cross-functional teams to enhance orthopedic outcomes and proc...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$401K - $500K+*

Join a team that's shaping the future of infrastructure engineering by leading efforts for cloud platforms, scaling developer experiences, and unlocking transformative AI solutions to enhance producti...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$112K - $179K *

Lead the charge in managing complex IT projects from concept to implementation, ensuring timely delivery and compliance with federal standards. Collaborate with stakeholders to drive project success i...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$200K - $245K *

Pioneer data-driven engineering for our Autonomy Data Flywheel initiative, overseeing the entire lifecycle to enhance AI-driven operations. Collaborate with cross-functional teams to achieve quality a...

RemoteRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Transportation

$110K - $130K *

Join a team that's shaping innovative products by translating customer needs into actionable solutions. Collaborate with cross-functional teams to prioritize and deliver high-quality outcomes in a dyn...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Enterprise Technology

$114K - $151K *

Unlock potential by leading the HV overhead switchgear portfolio, driving product strategy, market development, and cross-functional collaboration to achieve profitable growth and enhance utility solu...

United StatesRemote

Reposted 4 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Champion the vision and strategy for AI-powered products, driving their roadmap and delivery while mentoring peers. Leverage AI tools to enhance decision-making and product lifecycle management, ensur...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.