Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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1,000+

Director, Project Management Jobs in Mississippi

Sort By: Relevance

$135K - $160K *

Drive strategic initiatives by developing KPI frameworks and operational dashboards, analyzing performance data, and collaborating across teams to enhance business outcomes and support informed decisi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$216K - $318K *

Champion the evolution of AI Platforms, leading a dynamic team to enhance AI integration and productivity. Drive strategic initiatives that empower engineers and elevate member experiences through inn...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$88K - $105K *

Elevate your career by leading integrated planning and scheduling efforts, ensuring seamless execution of complex manufacturing processes while collaborating across multiple functions to meet customer...

3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$180K - $220K *

Transform organizational change by leading enterprise-wide initiatives that enhance workforce capabilities and drive AI adoption. Collaborate with senior leaders to design impactful training programs...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Lead and manage design-build projects, ensuring timely completion within budget while meeting client objectives and contractual obligations. Oversee scope development, financial performance, and compl...

United StatesRemote

2 days ago

  •   15+ years exp.  •   Transportation

$150K - $180K *

Transform the future of revenue accounting by leading the integration of consumer revenue streams into a unified, automated process. Drive accuracy and efficiency while building a high-performing team...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$175K - $215K *

Shape the future of global partnerships by leading strategic account management, driving growth, and fostering executive relationships. Oversee program success and team leadership to deliver exception...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $120K *

Elevate your storytelling skills by crafting compelling proposals and presentations. Collaborate with cross-functional teams to communicate our value to clients, while managing resources and optimizin...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$97K - $146K *

Accelerate progress at a dynamic manufacturing environment by leading product change control initiatives, optimizing inventory, and ensuring seamless cross-functional collaboration to enhance operatio...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Lead the enhancement of finance systems in a dynamic environment, focusing on optimizing NetSuite and integrating additional solutions. This role involves strategy, system configuration, and process i...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $225K *

Tackle the procurement lifecycle for mission-critical cooling equipment in data centers. Lead strategic initiatives, supplier performance, and operational excellence, while managing risks and driving...

RemoteRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$124K - $224K *

Unlock potential by leading revenue operations, bridging sales, finance, and analytics. Drive forecasting, pipeline management, and team development to enhance business performance and ensure data int...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Energy & Utilities

$75K - $100K *

Drive operational excellence by managing maintenance and field service projects, ensuring timely delivery and compliance with safety standards while collaborating with cross-functional teams to enhanc...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$70K - $105K *

Collaborate with cross-functional teams to drive project execution and operational excellence in medical communications. Leverage your project management skills to ensure timely delivery and high-qual...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $209K *

Lead the product strategy and delivery for a comprehensive Workday ecosystem. Manage a team of product managers to enhance HR capabilities, ensuring alignment with enterprise priorities and improving...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$168K - $240K *

Lead total rewards strategy for a complex global healthcare tech firm. Drive compensation and benefits governance, align workforce investment with business goals, and ensure compliance while fostering...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $120K *

Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Champion data-driven decision-making by establishing a unified product metrics framework. Collaborate across teams to enhance product health insights, streamline reporting, and drive strategic initiat...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$172K - $287K *

Join us to shape the future of pharmacy by leading product strategy and innovation. Drive growth and commercialization for a diverse portfolio of healthcare technology solutions, influencing enterpris...

RemoteRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$225K - $295K *

Accelerate progress at the forefront of contract lifecycle management by driving innovation and strategic solutions. Collaborate with sales teams to enhance customer satisfaction and market leadership...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$135K - $150K *

Elevate your career by leading product operations, enhancing processes, and driving AI adoption. Collaborate with cross-functional teams to optimize product delivery and analytics, ensuring seamless c...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$170K - $200K *

Champion the security design and delivery for hyperscale projects, ensuring comprehensive protection through physical and electronic systems. Collaborate with cross-functional teams to establish stand...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K - $145K *

Lead the onboarding function for diverse customer segments, managing a team to ensure a seamless transition from contract to go-live. Collaborate cross-functionally to enhance processes and drive cust...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$80K - $95K *

Manage integrated master schedules and coordinate cross-functional teams to ensure project alignment and timely deliverables. Proactively assess risks, facilitate client communications, and contribute...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Elevate client satisfaction by managing seamless transitions from implementation to ongoing administration, ensuring operational excellence and proactive risk management throughout the hypercare phase...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.