Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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$110K - $130K *

Empower healthcare IT delivery by managing a dynamic team, ensuring operational excellence, and driving EMR performance. Collaborate with clinical stakeholders to enhance patient care through effectiv...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $250K *

Transform financial services by leading complex banking operations and technology projects. Collaborate with clients to enhance performance, drive innovation, and shape a new practice within a dynamic...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Business Services

$120K - $145K *

Champion the development and execution of scalable Product and Pricing systems, overseeing integrations across platforms while driving business outcomes and ensuring compliance with enterprise standar...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform the future of hygienic sensors by leading product strategy, collaborating with engineering, and driving market success. Engage with customers and stakeholders to ensure product alignment wit...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$150K - $180K *

Elevate your career by leading strategic client relationships and driving growth in a dynamic architecture and engineering firm. This senior role focuses on account management, project excellence, and...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$150K - $180K *

Elevate data privacy standards by leading a comprehensive privacy program. Collaborate across teams to integrate privacy-by-design principles, enhance data governance, and ensure compliance while enab...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Transform healthcare analytics by leading the development of APR-DRG audit criteria. Collaborate with cross-functional teams to enhance payment integrity through data-driven insights and innovative so...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$123K - $169K *

Drive your career with end-to-end management of new product development programs, ensuring alignment across teams and delivering innovative solutions for critical digital infrastructure in a dynamic e...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Elevate global post-market surveillance by leading a team focused on safety, compliance, and performance of medical devices. Drive field actions, analyze data, and collaborate cross-functionally to en...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$198K - $233K *

Shape AI product strategy by synthesizing trends, customer needs, and tech capabilities. Collaborate with engineering and design to drive innovation, enabling AI solutions that deliver genuine custome...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$122K - $177K *

Lead coding operations and education initiatives to ensure compliance, accuracy, and optimal reimbursement across the organization. Manage staff training and oversee coding standards while collaborati...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$350K - $398K *

Drive impactful clinical trials in ophthalmology with leadership in study design, execution, and biomarker strategy. Collaborate cross-functionally to ensure timely delivery and regulatory compliance...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Help us shape the future of pulmonary care by leveraging your clinical expertise to drive product development, enhance workflows, and ensure effective solutions for COPD, asthma, and other pulmonary c...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $218K *

Join a team that's transforming the automotive industry by leading agile teams to deliver innovative, data-driven manufacturing solutions while fostering a culture of trust and continuous improvement...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$126K - $189K *

Join a team that's leading provider enrollment operations, ensuring timely onboarding, compliance, and accuracy. Drive strategic initiatives and enhance operational efficiency across networks while co...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Transform OEM partnerships by driving strategic growth and innovative solutions. Leverage market insights and relationship-building skills to negotiate impactful deals and collaborate with senior lead...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$88K - $105K *

Join a team that's shaping the future of utility solutions by managing complex projects and ensuring successful deployment of power systems. Take the lead in technical support while fostering strong r...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$90K - $110K *

Elevate utility project success by managing technical support and project coordination for power rent solutions, ensuring high standards of safety, communication, and customer satisfaction while overs...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$109K - $163K *

Champion the development of partner products and services, managing the entire product lifecycle to enhance customer experiences while collaborating across teams to ensure compliance and successful pr...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $209K *

Pioneer cross-functional initiatives in business operations, translating leadership priorities into actionable plans. Drive strategic execution, stakeholder management, and data-driven insights to enh...

Reposted yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Unlock the potential of streamlined warehouse operations and repair processes. Drive efficiency through parts management and technical support, enhancing customer satisfaction and reinforcing service...

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Staffing

$143K - $243K *

Champion innovative clinical strategies in specialty pharmacy, overseeing services and solutions to enhance client value and outcomes. Collaborate with cross-functional teams to drive program performa...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate your career by leading financial planning and analysis, managing budgets, and driving strategic insights. Collaborate with cross-functional teams to enhance operational performance and deliver...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$270K - $280K *

Join a team that's driving clinical excellence by overseeing trial execution, managing timelines, budgets, and CROs. Collaborate with stakeholders to ensure compliance and quality while mentoring team...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$151K - $314K *

Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.