Find $100K+ Jobs in Michigan

Explore professional opportunities in Michigan with salaries of $100,000 or more. From Detroit and Grand Rapids to Ann Arbor, Lansing, and communities across the state, Ladders helps experienced professionals discover vetted roles with competitive compensation.

Explore Michigan Opportunities Across Industries

Michigan’s economy spans automotive and advanced manufacturing, healthcare, technology, finance, education, energy, and professional services. Browse senior-level and specialized openings that match your experience, skills, and career goals.

Search by Location and Career Goals

Find opportunities in major employment centers such as Detroit, Ann Arbor, Grand Rapids, and Lansing, or consider roles elsewhere in Michigan. Compare positions by responsibilities, location, work arrangement, and compensation to focus your search.

Advance Your Career with Ladders

Ladders focuses on vetted professional jobs paying $100,000 or more. Create a profile, refine your search, and explore Michigan roles that align with your expertise and next career move. Job availability and compensation vary by employer and position.

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$255K - $424K *

Shape the future of global site management by leading strategic initiatives, optimizing clinical trial performance, and driving innovation across diverse teams and regions to enhance patient outcomes...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$255K - $424K *

Lead the charge in global site management, driving strategic vision and operational excellence across clinical development. Collaborate with senior leadership to optimize performance, enhance quality...

1 week ago

  •   15+ years exp.  •   Pharmaceuticals & Biotech

$195K - $208K *

Reimagine user experiences by leading design for core product features, ensuring seamless integration and customer delight. Collaborate across teams to enhance engagement and trust, shaping the future...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$110K - $130K *

Champion enablement initiatives across Technical and Sales domains, partnering with experts to define and execute programs. Lead content development, delivery, and continuous improvement efforts to en...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Drive strategic planning and operational excellence for a dynamic Marketing & Communications team. Own budgeting, resource management, and cross-functional partnerships while leading initiatives that...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Transform project delivery by overseeing all phases of civil construction, managing client relations, financials, and compliance while ensuring safety and quality standards are met throughout the proj...

1 week ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$120K *

Join a team that's driving impactful cross-functional initiatives by leading strategic delivery efforts. Leverage your project management expertise to align complex projects with enterprise priorities...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$138K - $165K *

Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$236K - $354K *

Elevate clinical operations by leading global study management, driving strategic vision, and ensuring high-quality trial execution. Collaborate across teams to optimize resources and foster a culture...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Drive financial governance by tracking budgets, analyzing variances, and generating reports in a federal mission environment. Collaborate with cross-functional teams to ensure compliance and support e...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$184K - $230K *

Lead the charge in transforming business readiness and deployment excellence across the Americas, ensuring seamless Oracle E-Business Suite upgrades while aligning regional priorities with global stra...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $219K *

Lead clinical laboratory operations for precision medicine projects, ensuring timely deliverables and risk management across therapeutic areas. Collaborate with cross-functional teams to support clini...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$145K - $220K *

Drive the development and commercialization of innovative digital solutions for federal clients. Lead cross-functional teams, engage with customers, and manage the full product lifecycle from concept...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Business Services

$179K - $248K *

Lead the charge in operationalizing strategy and driving cross-division initiatives. Collaborate with senior stakeholders to enhance efficiency and client satisfaction in a fast-paced corporate travel...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Accelerate progress at the forefront of automotive innovation by leading a dynamic Simultaneous Development Team. Drive project success through effective communication, risk management, and customer e...

3 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Champion project success by leading clinical trials from initiation to closure, ensuring compliance with budgets, timelines, and regulations while fostering collaboration among stakeholders and team m...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Lead the charge in shaping a new Technical Program Management team, guiding TPMs to deliver impactful results while fostering collaboration across Engineering and Product. Drive strategic planning and...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$175K - $220K *

Lead and develop a high-performing R&D project management team, overseeing a diverse portfolio of innovative projects. Drive effective execution while mentoring staff and enhancing cross-business proc...

RemoteRemote

Reposted 2 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Elevate your career by managing K-12 construction projects from inception to completion, ensuring quality, safety, and budget adherence while collaborating with diverse stakeholders to create impactfu...

2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$90K - $110K *

Help us drive project success by managing AV integration projects from inception to completion, ensuring timely delivery, budget adherence, and client satisfaction while fostering collaboration within...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$88K - $105K *

Lead the charge in managing service and modification projects from sales handoff to closeout, ensuring customer satisfaction and project success through effective schedule and budget management across...

4 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$209K - $239K *

Drive complex technical initiatives and lead multi-year integration strategies to enhance platform capabilities, ensuring alignment with business objectives and fostering a culture of excellence in Te...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Lead Oracle Cloud EPM projects, ensuring timely delivery and high quality. Collaborate with stakeholders and manage resources to achieve project objectives, fostering team success and effective commun...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$275K - $300K *

Transform customer experiences by leading the multi-location product initiative, driving strategy, and developing innovative solutions that scale across the platform for diverse users, empowering them...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$100K - $120K *

Unlock your potential as a Project Manager, leading complex, cross-functional projects. Oversee multiple initiatives, ensuring timely delivery and budget adherence while mentoring team members and enh...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100,000-plus jobs can I find in Michigan?question toggle

    Listings may include leadership, technology, engineering, healthcare, finance, sales, and other specialized professional roles. Availability depends on current employer postings.

  • Which Michigan cities have professional job opportunities?question toggle

    Opportunities may be available in Detroit, Grand Rapids, Ann Arbor, Lansing, and other Michigan communities. Check each listing for its location and work arrangement.

  • Are all jobs on Ladders in Michigan guaranteed to pay at least $100,000?question toggle

    Ladders focuses on vetted professional jobs paying $100,000 or more, but review each listing for its specific compensation details and eligibility requirements.

  • Can I find remote or hybrid jobs based in Michigan?question toggle

    Some employers may offer remote or hybrid arrangements. Work location and flexibility vary by role, so confirm the details in each job posting.