Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$145K - $175K *

Join a team that's redefining AI-driven solutions by leading product development for an innovative tech concierge. Drive the evolution of agent capabilities, ensuring quality and reliability while col...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$150K - $180K *

Optimize engagement and monetization strategies for an AI-driven product, transforming customer interactions into measurable growth. Lead cross-functional teams to innovate and implement effective use...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$217K - $298K *

Lead the charge in shaping Root's platform and AI engineering strategy, overseeing critical infrastructure and driving operational excellence across teams to deliver intelligent products at scale...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Enterprise Technology

$100K - $115K *

Transform your career by leading financial strategy and operations for innovative service lines. Collaborate with senior leaders to enhance profitability, oversee budgeting, and drive growth initiativ...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Champion the strategy and execution of clinical data management, ensuring data integrity and compliance for global marketing applications. Lead a dynamic team, oversee vendor relationships, and drive...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Transform global partner strategies to drive revenue and market share through innovative go-to-market models, collaborating with key stakeholders to establish impactful partnerships and optimize sales...

United StatesRemote

3 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$125K - $169K *

Lead the charge in enhancing customer success initiatives by driving engagement, optimizing processes, and fostering strong relationships. Collaborate with cross-functional teams to ensure exceptional...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$180K - $200K *

Accelerate progress at regional Professional Services by leading teams, driving growth and quality in consulting engagements while fostering strategic partnerships and developing innovative service of...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$131K - $196K *

Unlock potential by developing AI-driven applications and data pipelines. Collaborate with teams to enhance operational efficiency through innovative technical solutions, ensuring quality and scalabil...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Food & Beverages

$145K - $175K *

Empower our marketing evolution by leading product strategies that enhance customer engagement and drive growth. Collaborate across teams to innovate marketing capabilities and deliver personalized ex...

3 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Transform enterprise risk management by leading critical audits and enhancing controls. Maintain relationships with external auditors and foster compliance initiatives to mitigate risk across all oper...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$125K - $150K *

Drive operational excellence by leading supply chain strategies, procurement, and logistics. Collaborate with cross-functional teams to enhance processes, manage vendor relationships, and ensure resou...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$132K - $232K *

Redefine career mobility strategies by integrating talent marketplace capabilities, enabling associates to explore growth opportunities through data-informed solutions and collaborative practices acro...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Business Services

$132K - $232K *

Champion enterprise career mobility strategies by designing and implementing talent marketplace capabilities. Collaborate across teams to enhance associate growth experiences through data-informed sol...

Yesterday

  •   8 - 10 years exp.  •   Business Services

$73K - $122K *

Lead high-impact fraud initiatives, shaping product vision and strategy. Collaborate with cross-functional teams to prioritize and deliver key capabilities, ensuring continuous improvement and alignme...

Massachusetts, USRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$154K - $193K *

Drive AI transformation by building client relationships, leading engagements, and delivering results. Own the sales process from prospecting to execution, ensuring successful integration of AI soluti...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$120K - $225K *

Engage with stakeholders to create compelling video content from concept to final cut. Collaborate across teams, manage production, and ensure high editorial standards while translating complex topics...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$109K - $145K *

Drive impactful audit engagements by collaborating with leaders to enhance risk management and governance. Lead complex audits, communicate findings, and foster relationships while leveraging data ana...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$174K - $356K *

Empower local clients with your expertise in accounting advisory services. Lead high-impact projects, transform financial operations, and drive business growth while mentoring a collaborative team in...

3 weeks ago

  •   11 - 15 years exp.  •   Business Services

$122K *

Champion project success by leading interdisciplinary teams to deliver innovative solutions in the biotech and pharma sectors. Drive milestone achievement, manage budgets, and ensure compliance with p...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$161K - $242K *

Join a team that's driving strategic initiatives and digital transformation. Collaborate with senior leaders to tackle complex challenges, influence decision-making, and ensure successful execution of...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$120K - $150K *

Transform the landscape of dental negotiations by leading strategic partnerships with payers, optimizing contracts, and driving revenue growth through data-driven insights and collaborative execution...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$102K - $152K *

Transform executive support by leading a dynamic team of EAs, enhancing processes, and driving strategic initiatives that align with company goals while fostering a collaborative culture...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Information Technology

$220K - $290K *

Accelerate the development of autonomous systems by leading systems engineering strategies, aligning cross-functional teams, and ensuring rigorous safety and performance standards throughout the produ...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$220K - $290K *

Empower innovation by leading systems engineering for autonomous aviation. Drive strategy, manage cross-functional teams, and ensure safety and performance in developing cutting-edge technologies for...

1 week ago

  •   11 - 15 years exp.  •   Aerospace & Defense

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.