Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$110K - $130K *

Champion innovative engineering solutions by leading multi-site projects, enhancing infrastructure, and driving operational improvements to ensure safety and efficiency across facilities...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$130K - $170K *

Manage execution of cross-functional projects, driving product development from concept to launch. Collaborate with teams to ensure timely delivery, maintain project tracking, and communicate effectiv...

4 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$217K - $263K *

Unlock your potential as a strategic leader in program management, driving the execution and integration of product development strategies for pivotal assets. Collaborate within cross-functional teams...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$190K - $220K *

Champion financial excellence by leading a dynamic team, driving strategic analysis, and leveraging AI to enhance decision-making for a diverse portfolio of clients in a fast-paced, remote environment...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Business Services

$134K - $219K *

Empower data management excellence by leading cross-functional teams, ensuring compliance, and driving process improvements across multiple clinical trials while mentoring staff and maintaining high d...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion medium-to-large projects by leading cross-functional teams to achieve strategic goals. Manage all phases from initiation to stabilization, ensuring alignment, accountability, and measurable o...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$150K - $160K *

Drive project success by managing integrated delivery across AI task orders, overseeing multidisciplinary teams, and ensuring adherence to quality standards while maintaining project roadmaps and sche...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Lead end-to-end client engagements for complex AI and digital projects, managing multiple implementations while ensuring timely delivery and exceeding client expectations. Collaborate with cross-funct...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$200K - $250K *

Join a team that's shaping growth strategies for Federal Civilian accounts. Leverage your expertise in federal markets to drive business development, capture opportunities, and enhance customer relati...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $95K *

Lead the charge in program management excellence, ensuring seamless operations and compliance across diverse teams while supporting critical Air Force contract initiatives and rapid-response readiness...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Technical Services

$100K - $139K *

Drive your career forward by providing technical support for electrical construction and maintenance projects. Collaborate with cross-functional teams, ensure compliance with standards, and enhance fa...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$68K - $102K *

Support our team by managing project coordination, ensuring timely deliveries, and enhancing customer satisfaction through effective communication and problem-solving. Play a key role in driving opera...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$170K - $267K *

Pioneer transformative change by leading technology process optimization, ensuring operational transparency, and fostering collaboration across teams. Drive efficiency and improve control within a glo...

Reposted 1 week ago

  •   11 - 15 years exp.  •   Finance & Insurance

$190K - $230K *

Pioneer strategic data governance initiatives, building ownership models and partnerships that enhance data integrity and compliance across the organization. Lead a dynamic team to champion innovative...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Consumer Technology

$150K - $180K *

Reimagine client partnerships by managing complex relationships, driving performance, and leading recovery strategies. Collaborate with executives to ensure client success and identify growth opportun...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$75K - $115K *

Elevate project success by leading technical AI initiatives, managing diverse teams, and ensuring alignment across stakeholders to deliver innovative solutions that drive business value in dynamic env...

3 weeks ago

  •   5 - 7 years exp.  •   Media

$110K - $130K *

Elevate regulatory project management by leading cross-functional teams to ensure timely execution of complex pharmaceutical and medical device initiatives, aligning with global regulatory standards a...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$134K - $241K *

Engage in the safe and efficient management of large-scale construction projects. Oversee field activities, ensure compliance with safety and environmental standards, and coordinate resources to achie...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Real Estate & Construction

$120K - $145K *

Shape the future of discovery operations by leveraging your legal expertise and leadership skills to enhance service delivery and team performance, ensuring top-quality results and efficient workflows...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$222K - $278K *

Join a team that's redefining revenue cycle management by leading strategic initiatives, enhancing operational efficiency, and driving financial performance across a dynamic healthcare landscape focus...

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$92K - $160K *

Lead the delivery of strategic technology initiatives, collaborating across teams to optimize New Business and Underwriting processes. Ensure projects meet scope, budget, and regulatory commitments wh...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$63K - $102K *

Drive the management of multiple clinical research studies, ensuring compliance and quality. Serve as the key liaison among stakeholders, oversee trial initiation, patient recruitment, and budget mana...

4 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$63K - $102K *

Lead the charge in managing clinical research projects, overseeing staff, and ensuring compliance with protocols. Collaborate with stakeholders to enhance mental health interventions and streamline st...

6 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$150K - $180K *

Lead the charge in construction quality management for a large-scale data center portfolio. Drive the establishment of quality standards, ensure compliance, and oversee a dedicated team of Site Qualit...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$196K - $269K *

Champion innovative strategies in incentive compensation and sales planning, driving performance and customer engagement across diverse teams. Collaborate with leadership to optimize field execution a...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.